Harvesting Human Prostate Tissue Material and Culturing Primary Prostate Epithelial Cells

2016 ◽  
pp. 181-201 ◽  
Author(s):  
Fiona M. Frame ◽  
Davide Pellacani ◽  
Anne T. Collins ◽  
Norman J. Maitland
Keyword(s):  
Epithelial Cells ◽  
Prostate Tissue ◽  
Human Prostate ◽  
Prostate Epithelial Cells ◽  
Human Prostate Tissue ◽  
Tissue Material

scholarly journals Proteoglycan Expression in Normal Human Prostate Tissue and Prostate Cancer

ISRN Oncology ◽  
2013 ◽  
Vol 2013 ◽  
pp. 1-9 ◽  
Author(s):  
Anastasia V. Suhovskih ◽  
Lyudmila A. Mostovich ◽  
Igor S. Kunin ◽  
Mekhrozhiddin M. Boboev ◽  
Galina I. Nepomnyashchikh ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Epithelial Cells ◽  
Cell Surface ◽  
Mammalian Cells ◽  
Expression Patterns ◽  
Prostate Tissue ◽  
Human Prostate ◽  
Pcr Analysis ◽  
Human Prostate Tissue ◽  
Normal Human

Proteoglycans (PGs) are expressed on the cell surface and extracellular matrix of all mammalian cells and tissues, playing an important role in cell-cell and cell-matrix interactions and signaling. Changes in the expression and functional properties of individual PGs in prostate cancer are shown, although common patterns of PGs expression in normal and tumour prostate tissues remain unknown. In this study, expression of cell surface and stromal proteoglycans (glypican-1, perlecan, syndecan-1, aggrecan, versican, NG2, brevican, decorin, and lumican) in normal tissue and prostate tumours was determined by RT-PCR analysis and immunostaining with core protein- and GAG-specific antibodies. In normal human prostate tissue, versican, decorin, and biglycan were predominant proteoglycans localised in tissue stroma, and syndecan-1 and glypican-1 were expressed mainly by epithelial cells. In prostate tumours, complex changes in proteoglycans occur, with a common trend towards decrease of decorin and lumican expression, overall increase of syndecan-1 and glypican-1 expression in tumour stroma along with its disappearance in tumour epithelial cells, and aggrecan and NG2 expressions in some prostate tumours. All the changes result in the highly individual proteoglycan expression patterns in different prostate tumours, which may be potentially useful as molecular markers for prostate cancer personalised diagnosis and treatment.

444: Identification of Genes Involved in Androgen Receptor Mutant-Induced Tumorigenesis of Human Prostate Epithelial Cells

2006 ◽  
Vol 175 (4S) ◽  
pp. 144-144
Author(s):  
Xu-Bao Shi ◽  
Lingru Xue ◽  
Clifford G. Tepper ◽  
Ralph W. deVere White
Keyword(s):  
Androgen Receptor ◽  
Epithelial Cells ◽  
Human Prostate ◽  
Prostate Epithelial Cells ◽  
Receptor Mutant

Characteristics of nonneoplastic human prostate tissue transplanted into nude mice

The Prostate ◽  
1998 ◽  
Vol 37 (2) ◽  
pp. 109-115 ◽  
Author(s):  
Yasuyuki Yamada ◽  
Keiichi Tozawa ◽  
Lin Cui ◽  
Satoru Takahashi ◽  
Tomoyuki Shirai ◽  
...  
Keyword(s):  
Nude Mice ◽  
Prostate Tissue ◽  
Human Prostate ◽  
Human Prostate Tissue

MP36-16 THE EXPRESSION OF BETA-DEFENSIN 131 PROMOTES INNATE IMMUNITY IN HUMAN PROSTATE EPITHELIAL CELLS

2016 ◽  
Vol 195 (4S) ◽  
Author(s):  
Jung Hoon Kim ◽  
Kyeoung-Hwa Kim ◽  
Hae Jong Kim ◽  
Jaekhyouk Lee ◽  
Soon Chul Myung ◽  
...  
Keyword(s):  
Innate Immunity ◽  
Epithelial Cells ◽  
Human Prostate ◽  
Prostate Epithelial Cells

scholarly journals 1044 Molecular characterization of radiation-induced transformation of human prostate epithelial cells

1995 ◽  
Vol 32 ◽  
pp. 245
Author(s):  
Michael Kuettel ◽  
Peter Thraves ◽  
Sarada Prasad ◽  
Susan Varghese ◽  
Anatoly Dritschilo
Keyword(s):  
Epithelial Cells ◽  
Molecular Characterization ◽  
Human Prostate ◽  
Prostate Epithelial Cells ◽  
Radiation Induced

E-cadherin expression and PSA secretion in human prostate epithelial cells

2001 ◽  
Vol 29 (4) ◽  
pp. 287-292 ◽  
Author(s):  
Diane Krill ◽  
Angela Thomas ◽  
Su-Ping Wu ◽  
Rajiv Dhir ◽  
Michael J. Becich
Keyword(s):  
Epithelial Cells ◽  
Human Prostate ◽  
Prostate Epithelial Cells ◽  
E Cadherin
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