Role of TRs in Zebrafish Development

2018 ◽  
pp. 287-298 ◽  
Author(s):  
Federica Marelli ◽  
Luca Persani
Keyword(s):  
Zebrafish Development

scholarly journals The Role of Nesprin in the Facial Branchiomotor Neuron (FBMN) Migration of Danio rerio (zebrafish) development

2019 ◽  
Vol 33 (S1) ◽  
Author(s):  
Aishwarya Nugooru ◽  
Daniel E. Conway ◽  
Gregory Walsh
Keyword(s):  
Danio Rerio ◽  
Zebrafish Development

scholarly journals Role of MNS1 in cilia motility during zebrafish development

2017 ◽  
Vol 145 ◽  
pp. S86
Author(s):  
Eduardo Pulgar ◽  
Miguel Concha
Keyword(s):  
Zebrafish Development

scholarly journals The role of meis1 in primitive and definitive hematopoiesis during zebrafish development

Haematologica ◽  
2010 ◽  
Vol 96 (2) ◽  
pp. 190-198 ◽  
Author(s):  
A. Cvejic ◽  
J. Serbanovic-Canic ◽  
D. L. Stemple ◽  
W. H. Ouwehand
Keyword(s):  
Zebrafish Development ◽  
Definitive Hematopoiesis

The Role of Survivin in Angiogenesis during Zebrafish Embryonic Development.

Blood ◽  
2006 ◽  
Vol 108 (11) ◽  
pp. 1812-1812
Author(s):  
Anskar Y.H. Leung ◽  
Alvin C.H. Ma ◽  
Anming Meng ◽  
Catherine M. Verfaillie ◽  
Raymond Liang
Keyword(s):  
Caspase 3 ◽  
Survivin Expression ◽  
Tunel Staining ◽  
Vegf Receptor ◽  
Vascular Endothelial ◽  
Cell Stage ◽  
Translation Inhibition ◽  
Zebrafish Development ◽  
Endothelial Growth Factor

Abstract We investigated the role of survivin in angiogenesis during zebrafish development. Morpholinos (MOs) targeting the 5′ untranslated region (UTR) (SurUTR) and sequences flanking the initiation codon (SurATG) of zebrafish survivin-1 gene were injected into embryos at 1–4 cell stage. Vasculature was examined by microangiography and GFP expression in Tg(fli1:GFP) embryos. In embryos co-injected with SurUTR and SurATG-MOs, vasculogenesis was intact but angiogenesis was markedly perturbed, especially in the inter-segmental vessels (ISV) of the trunk, the inner optic circle and optic veins of developing eyes and the sub-intestinal vessels. Apoptosis was increased, as shown by TUNEL staining and increase in caspase-3 activity. Efficacy of SurUTR and SurATG-MOs was demonstrated by translation inhibition of co-injected 5′UTR survivin:GFP plasmids. The phenotypes could be recapitulated by splice-site MO targeting the exon2-intron junction of survivin gene and rescued by survivin mRNA. Injection of human vascular endothelial growth factor (VEGF) protein induced ectopic angiogenesis and increased survivin expression, whereas treatment with a VEGF receptor inhibitor markedly reduced angiogenesis and suppressed survivin expression. Hematopoietic cell development at 18 hpf, before the onset of circulation, was unaffected in the survivin MO injected embryos. In conclusion, survivin is involved in angiogenesis during zebrafish development and is under VEGF regulation.

The role of phospholipase C gamma 1 in primitive hematopoiesis during zebrafish development

2007 ◽  
Vol 35 (3) ◽  
pp. 368-373 ◽  
Author(s):  
Alvin C.H. Ma ◽  
Raymond Liang ◽  
Anskar Y.H. Leung
Keyword(s):  
Phospholipase C ◽  
Zebrafish Development ◽  
Primitive Hematopoiesis ◽  
Phospholipase C Gamma

Role of phosphatidylinositol 5-phosphate 4-kinase α in zebrafish development

2013 ◽  
Vol 45 (7) ◽  
pp. 1293-1301 ◽  
Author(s):  
Dalila Elouarrat ◽  
Yme U. van der Velden ◽  
David R. Jones ◽  
Wouter H. Moolenaar ◽  
Nullin Divecha ◽  
...  
Keyword(s):  
Zebrafish Development

scholarly journals Characterisation of expression patterns and functional role of Cactin in early zebrafish development

2010 ◽  
Vol 10 (4-5) ◽  
pp. 199-206 ◽  
Author(s):  
Paola Atzei ◽  
Fan Yang ◽  
Ross Collery ◽  
Breandan N. Kennedy ◽  
Paul N. Moynagh
Keyword(s):  
Functional Role ◽  
Expression Patterns ◽  
Zebrafish Development

scholarly journals The role of survivin2 in primitive hematopoiesis during zebrafish development

Leukemia ◽  
2009 ◽  
Vol 23 (4) ◽  
pp. 712-720 ◽  
Author(s):  
A C H Ma ◽  
M I S Chung ◽  
R Liang ◽  
A Y H Leung
Keyword(s):  
Zebrafish Development ◽  
Primitive Hematopoiesis
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