Detection of Proteoforms Using Top-Down Mass Spectrometry and Diagnostic Ions

2019 ◽  
pp. 173-183 ◽  
Author(s):  
Didia Coelho Graça ◽  
Ralf Hartmer ◽  
Wolfgang Jabs ◽  
Alexander Scherl ◽  
Lorella Clerici ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Top Down ◽  
Diagnostic Ions ◽  
Top Down Mass Spectrometry

TopPIC Gateway: A Web Gateway for Top-Down Mass Spectrometry Data Interpretation

2020 ◽  
Author(s):  
In Kwon Choi ◽  
Eroma Abeysinghe ◽  
Eric Coulter ◽  
Suresh Marru ◽  
Marlon Pierce ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Data Interpretation ◽  
Mass Spectrometry Data ◽  
Top Down ◽  
Top Down Mass Spectrometry

scholarly journals Characterization and Quantification of Intact 26S Proteasome Proteins by Real-Time Measurement of Intrinsic Fluorescence Prior to Top-down Mass Spectrometry

PLoS ONE ◽  
2013 ◽  
Vol 8 (3) ◽  
pp. e58157 ◽  
Author(s):  
Jason D. Russell ◽  
Mark Scalf ◽  
Adam J. Book ◽  
Daniel T. Ladror ◽  
Richard D. Vierstra ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Real Time ◽  
Time Measurement ◽  
Intrinsic Fluorescence ◽  
26S Proteasome ◽  
Top Down ◽  
Real Time Measurement ◽  
Top Down Mass Spectrometry

Top-down mass spectrometry

2008 ◽  
Vol 5 (1) ◽  
pp. 24-24 ◽  
Author(s):  
Allison Doerr
Keyword(s):  
Mass Spectrometry ◽  
Top Down ◽  
Top Down Mass Spectrometry

scholarly journals Quantifying Positional Isomers (QPI) by Top-Down Mass Spectrometry

2021 ◽  
Vol 20 ◽  
pp. 100070
Author(s):  
Andrea M. Brunner ◽  
Philip Lössl ◽  
Paul P. Geurink ◽  
Huib Ovaa ◽  
P. Albanese ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Positional Isomers ◽  
Top Down ◽  
Top Down Mass Spectrometry

Extensive Characterization of the Human Salivary Basic Proline-Rich Protein Family by Top-Down Mass Spectrometry

2018 ◽  
Vol 17 (9) ◽  
pp. 3292-3307 ◽  
Author(s):  
Alessandra Padiglia ◽  
Roberto Orrù ◽  
Mozhgan Boroumand ◽  
Alessandra Olianas ◽  
Barbara Manconi ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Protein Family ◽  
Top Down ◽  
Proline Rich Protein ◽  
Top Down Mass Spectrometry

Top-Down Mass Spectrometry for Trace Level Quantification of Staphylococcal Enterotoxin A Variants

2021 ◽  
Author(s):  
Donatien Lefebvre ◽  
François Fenaille ◽  
Déborah Merda ◽  
Kevin Blanco-Valle ◽  
Cécile Feraudet-Tarisse ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Staphylococcal Enterotoxin ◽  
Staphylococcal Enterotoxin A ◽  
Top Down ◽  
Trace Level ◽  
Top Down Mass Spectrometry

Towards understanding the formation of internal fragments generated by collisionally activated dissociation for top-down mass spectrometry

2021 ◽  
pp. 339400
Author(s):  
Benqian Wei ◽  
Muhammad A. Zenaidee ◽  
Carter Lantz ◽  
Rachel R. Ogorzalek Loo ◽  
Joseph A. Loo
Keyword(s):  
Mass Spectrometry ◽  
Top Down ◽  
Collisionally Activated Dissociation ◽  
Top Down Mass Spectrometry

scholarly journals Evaluation of top-down mass spectrometry and ion-mobility spectroscopy as a means of mapping protein-binding motifs within heparin chains

The Analyst ◽  
2020 ◽  
Vol 145 (8) ◽  
pp. 3090-3099 ◽  
Author(s):  
Yunlong Zhao ◽  
Igor A. Kaltashov
Keyword(s):  
Mass Spectrometry ◽  
Protein Binding ◽  
Ion Mobility ◽  
Structural Elements ◽  
Client Protein ◽  
Top Down ◽  
Binding Motifs ◽  
Ion Mobility Spectroscopy ◽  
High Degree ◽  
Top Down Mass Spectrometry

Identifying structural elements within glycosaminoglycans that enable their interaction with a specific client protein remains a challenging task due to the high degree of both intra- and inter-chain heterogeneity exhibited by this polysaccharide.

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