Affitins: Ribosome Display for Selection of Aho7c-Based Affinity Proteins

2019 ◽  
pp. 19-41 ◽  
Author(s):  
Valentina Kalichuk ◽  
Stanimir Kambarev ◽  
Ghislaine Béhar ◽  
Benjamin Chalopin ◽  
Axelle Renodon-Cornière ◽  
...  
Keyword(s):  
Ribosome Display ◽  
Selection Of ◽  
Affinity Proteins

Ribosome Display for the Selection of Sac7d Scaffolds

2011 ◽  
pp. 315-331 ◽  
Author(s):  
Barbara Mouratou ◽  
Ghislaine Béhar ◽  
Lauranne Paillard-Laurance ◽  
Stéphane Colinet ◽  
Frédéric Pecorari
Keyword(s):  
Ribosome Display ◽  
Selection Of

Selection of scFvs specific for HBV DNA polymerase using ribosome display

2004 ◽  
Vol 284 (1-2) ◽  
pp. 147-157 ◽  
Author(s):  
Myung-Shin Lee ◽  
Myung-Hee Kwon ◽  
Kyongmin Hwang Kim ◽  
Ho-Joon Shin ◽  
Sun Park ◽  
...  
Keyword(s):  
Dna Polymerase ◽  
Hbv Dna ◽  
Ribosome Display ◽  
Selection Of

Panning and selection of proteins using ribosome display

2001 ◽  
Vol 254 (1-2) ◽  
pp. 191-197 ◽  
Author(s):  
Gregory Coia ◽  
Luisa Pontes-Braz ◽  
Stewart D Nuttall ◽  
Peter J Hudson ◽  
Robert A Irving
Keyword(s):  
Ribosome Display ◽  
Selection Of

Selection of Single Chain Variable Fragments Specific for the Human-Inducible Costimulator Using Ribosome Display

2012 ◽  
Vol 168 (5) ◽  
pp. 967-979 ◽  
Author(s):  
Yangbin Pan ◽  
Weiping Mao ◽  
Xuanxuan Liu ◽  
Chong Xu ◽  
Zhijuan He ◽  
...  
Keyword(s):  
Single Chain ◽  
Ribosome Display ◽  
Inducible Costimulator ◽  
Single Chain Variable Fragments ◽  
Selection Of

scholarly journals Generation and Selection of a Panel of Pan-Filovirus Single-Chain Antibodies using Cell-Free Ribosome Display

2018 ◽  
Author(s):  
Adinarayana Kunamneni ◽  
Elizabeth C. Clarke ◽  
Chunyan Ye ◽  
Steven B. Bradfute ◽  
Ravi Durvasula
Keyword(s):  
Hemorrhagic Fever ◽  
Cross Reactivity ◽  
Free Ribosome ◽  
Rapid Diagnostics ◽  
Single Chain ◽  
Ribosome Display ◽  
Single Chain Antibodies ◽  
Single Chain Fv ◽  
New Generation ◽  
Selection Of

AbstractFiloviruses, which include ebolaviruses and marburgvirus, can cause outbreaks of highly lethal hemorrhagic fever. This disease causes significant morbidity and mortality in humans and non-human primates, with human fatality rates reaching 90% during some outbreaks. Currently, there are a lack of licensed vaccines or antivirals for these viruses. Since early symptoms of filovirus infection mimic more common diseases, there is a strong unmet public health and biodefense need for broad-spectrum filovirus rapid diagnostics. We have generated a panel of mouse single-chain Fv-antibodies (scFvs) to filovirus glycoproteins (GPs) using cell-free ribosome display and determined their cross-reactivity profiles to all known filovirus species. Two scFvs (4-2 and 22-1) were able to detect all known Ebolavirus and Marburgvirus species. This is the first report on ribosome display scFvs that can detect a broad set of filovirus GPs, which demonstrates their potential use in the development of a new generation of rapid diagnostic immunoassays.

scholarly journals Ribosome display and selection of single-chain variable fragments effectively inhibit growth and progression of microspheres in vitro and in vivo

2018 ◽  
Vol 109 (5) ◽  
pp. 1503-1512
Author(s):  
Shangke Huang ◽  
Lu Feng ◽  
Gaili An ◽  
Xiaojin Zhang ◽  
Zixuan Zhao ◽  
...  
Keyword(s):  
Single Chain ◽  
Ribosome Display ◽  
Single Chain Variable Fragments ◽  
Selection Of

Ribosome Display and Selection of Human Anti-Placental Growth Factor scFv Derived from Ovarian Cancer Patients

2010 ◽  
Vol 17 (5) ◽  
pp. 585-590 ◽  
Author(s):  
Fang Li ◽  
Pingping Su ◽  
Chao Lin ◽  
Hong Li ◽  
Jiajing Cheng ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Growth Factor ◽  
Cancer Patients ◽  
Placental Growth Factor ◽  
Ribosome Display ◽  
Selection Of
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