G4-FID: A Fluorescent DNA Probe Displacement Assay for Rapid Evaluation of Quadruplex Ligands

2009 ◽  
pp. 257-271 ◽  
Author(s):  
David Monchaud ◽  
Marie-Paule Teulade-Fichou
Keyword(s):  
Dna Probe ◽  
Rapid Evaluation ◽  
Displacement Assay

Ultrastructural analysis of the spatial distribution of MRNA

1992 ◽  
Vol 50 (1) ◽  
pp. 552-553
Author(s):  
Gary Bassell ◽  
Robert H. Singer
Keyword(s):  
Electron Microscopy ◽  
Spatial Distribution ◽  
In Situ Hybridization ◽  
High Resolution ◽  
Nucleic Acids ◽  
Colloidal Gold ◽  
Dna Probe ◽  
Nucleotide Analogs ◽  
Gold Particles

We have been investigating the spatial distribution of nucleic acids intracellularly using in situ hybridization. The use of non-isotopic nucleotide analogs incorporated into the DNA probe allows the detection of the probe at its site of hybridization within the cell. This approach therefore is compatible with the high resolution available by electron microscopy. Biotinated or digoxigenated probe can be detected by antibodies conjugated to colloidal gold. Because mRNA serves as a template for the probe fragments, the colloidal gold particles are detected as arrays which allow it to be unequivocally distinguished from background.

Early evidence of the development of primary care networks in England: a rapid evaluation study

2020 ◽  
Author(s):  
Judith Smith ◽  
Sarah Parkinson ◽  
Amelia Harshfield ◽  
Manbinder Sidhu
Keyword(s):  
Primary Care ◽  
Evaluation Study ◽  
Rapid Evaluation ◽  
Early Evidence

Rapid Evaluation of the Special Measures for Quality and Challenged Provider Regimes: A mixed-methods study

2020 ◽  
Author(s):  
Naomi Fulop ◽  
Estela Capelas Barbosa ◽  
Melissa Hill ◽  
Jean Ledger ◽  
Pei Li Ng ◽  
...  
Keyword(s):  
Mixed Methods ◽  
Mixed Methods Study ◽  
Rapid Evaluation

scholarly journals Microfluidic immunoassay for detection of serological antibodies: A potential tool for rapid evaluation of immunity against SARS-CoV-2

2020 ◽  
Vol 14 (6) ◽  
pp. 061507
Author(s):  
Hogi Hartanto ◽  
Minghui Wu ◽  
Miu Ling Lam ◽  
Ting-Hsuan Chen
Keyword(s):  
Rapid Evaluation ◽  
Microfluidic Immunoassay ◽  
Potential Tool

scholarly journals 54 The Rapid Evaluation of COVID-19 Vaccination in Emergency Departments for Underserved Patients Study

2021 ◽  
Vol 78 (2) ◽  
pp. S28
Author(s):  
R. Rodriguez ◽  
J. Torres ◽  
A. Chang ◽  
A. Haggins ◽  
M. Caldwell ◽  
...  
Keyword(s):  
Emergency Departments ◽  
Rapid Evaluation ◽  
Underserved Patients

scholarly journals Estimating the cooperativity of PROTAC-induced ternary complexes using 19F NMR displacement assay

2021 ◽  
Author(s):  
Guilherme Castro ◽  
Alessio Ciulli
Keyword(s):  
Ternary Complexes ◽  
19F Nmr ◽  
Fluorine Nmr ◽  
Competition Binding ◽  
Displacement Assay

Cooperativity is an important parameter to understand the ternary complexes formed by protein degraders. We developed fluorine NMR competition binding experiments to determine cooperativity of PROTACs. We show applicability to...

scholarly journals Species Differentiation of DNA using Dot-Blots with Biotinylated or 32P-Labeled Genomic DNA Probe

1987 ◽  
Vol 28 (3-4) ◽  
pp. 451-453
Author(s):  
P. Dybdahl Thomsen ◽  
K. Christensen
Keyword(s):  
Genomic Dna ◽  
Dna Probe ◽  
Species Differentiation
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