The Enhanced Pre- and Postnatal Development Study for Monoclonal Antibodies

2012 ◽  
pp. 185-200 ◽  
Author(s):  
Gerhard F. Weinbauer ◽  
Joerg Luft ◽  
Antje Fuchs
Keyword(s):  
Monoclonal Antibodies ◽  
Postnatal Development ◽  
Development Study

Rat pre- and postnatal development study with esomeprazole magnesium trihydrate: Lack of F1 bone effects

2015 ◽  
Vol 238 (2) ◽  
pp. S269
Author(s):  
J. Stewart ◽  
L. Jardine ◽  
P. Hall ◽  
M. Billger
Keyword(s):  
Postnatal Development ◽  
Development Study ◽  
Esomeprazole Magnesium

An Enhanced Pre- and Postnatal Development Study in Cynomolgus Monkeys with Tabalumab: A Human IgG4 Monoclonal Antibody

2015 ◽  
Vol 104 (3) ◽  
pp. 100-116 ◽  
Author(s):  
William J. Breslin ◽  
Kim G. Hilbish ◽  
Jennifer A. Martin ◽  
Carolyn A. Halstead ◽  
Deanna L. Newcomb ◽  
...  
Keyword(s):  
Monoclonal Antibody ◽  
Postnatal Development ◽  
Development Study ◽  
Cynomolgus Monkeys

Postnatal development of the rat cerebellar cortex studied with monoclonal antibodies

1986 ◽  
Vol 3 ◽  
pp. S36
Author(s):  
Kazumi Taniguchi ◽  
Koki Kawamura ◽  
Shinobu C. Fujita ◽  
Kunihiko Obata
Keyword(s):  
Monoclonal Antibodies ◽  
Postnatal Development ◽  
Cerebellar Cortex

Reproductive toxicity of ZishenYutai pill in rats: Perinatal and postnatal development study

2016 ◽  
Vol 81 ◽  
pp. 120-127 ◽  
Author(s):  
Li Zhou ◽  
Jie Zhou ◽  
Juan Jiang ◽  
Yang Yang ◽  
Qiuling Huang ◽  
...  
Keyword(s):  
Postnatal Development ◽  
Reproductive Toxicity ◽  
Development Study

scholarly journals Immunohistological characteristics of collagen, laminin and sialoadhesin in the rat submandibular salivary gland during ontogenesis

2003 ◽  
Vol 50 (4) ◽  
pp. 179-183
Author(s):  
Ivan Dozic ◽  
Miodrag Colic
Keyword(s):  
Extracellular Matrix ◽  
Monoclonal Antibodies ◽  
Salivary Gland ◽  
Postnatal Development ◽  
Basal Membrane ◽  
Myoepithelial Cells ◽  
Matrix Proteins ◽  
Submandibular Salivary Gland ◽  
Ductal Cells ◽  
Positive Reactivity

The aim of this study was to investigate the expression of collagen, laminin and sialoadhesin in the rat submandibular salivary gland during postnatal development (1st, 30th,and 60th day) by using various monoclonal antibodies (mAbs) RMC-23 (specific for collagen),a6?1 (specific for laminin) and ED3 (specific for sialoadhezin). These components of extracellular matrix were detected. RMC-23 mAb showed strong positivity to the basal membranes of the ductal system (intercalated, striated and excretory ducts) and of intersticium. Increased expression in the basal membrane of acini during development of glands was noted. Similar immunoreactivity was shown by?mAb but the intersticium showed a negative reaction to 1a6 this antibody. Positive reactivity of ?1a6 mAb of epithelial ductal cells, particularly of the neonatal animals, was found. In contrast to ? 1a6 and RMC23 mAbs, ED3 mAb was increasingly expressed in the myoepithelial cells during ontogenesis. Our findings regarding the immunoreactivity of collagens and laminins are in accordance with the findings of other autors. The very interesting finding of sialoadhesin in myoepithelial cells of the rat submandibular salivary gland, which is not described in literature and needs further investigation. Our results suggest that adhesion molecules and extracellular matrix proteins have an important biochemical role during postnatal development of the submandibular salivary gland.

scholarly journals REPRODUCTIVE STUDY II : PRENATAL AND POSTNATAL DEVELOPMENT STUDY WITH CANDOXATRIL IN SPRAGUE-DAWLEY RATS

1998 ◽  
Vol 23 (SupplementV) ◽  
pp. 671-679
Author(s):  
Masao HORIMOTO ◽  
Rieko ITO ◽  
Yuji ISOBE ◽  
Masanori SAKIMURA ◽  
Masakatsu TACHIBANA
Keyword(s):  
Postnatal Development ◽  
Sprague Dawley ◽  
Development Study ◽  
Sprague Dawley Rats ◽  
Prenatal And Postnatal Development ◽  
Reproductive Study

Rat pre- and postnatal development study with esomeprazole magnesium trihydrate: Lack of F1 bone effects

2015 ◽  
Vol 56 ◽  
pp. 25
Author(s):  
Jane Stewart ◽  
Lynne Jardine ◽  
Peter Hall ◽  
Martin Billger
Keyword(s):  
Postnatal Development ◽  
Development Study ◽  
Esomeprazole Magnesium

scholarly journals Monoclonal antibodies to nerve growth factor affect the postnatal development of the visual system.

1994 ◽  
Vol 91 (2) ◽  
pp. 684-688 ◽  
Author(s):  
N. Berardi ◽  
A. Cellerino ◽  
L. Domenici ◽  
M. Fagiolini ◽  
T. Pizzorusso ◽  
...  
Keyword(s):  
Monoclonal Antibodies ◽  
Nerve Growth Factor ◽  
Growth Factor ◽  
Visual System ◽  
Postnatal Development ◽  
Nerve Growth
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