Malarial Kinases: Novel Targets for In Silico Approaches to Drug Discovery

2013 ◽  
pp. 205-229 ◽  
Author(s):  
Kristen M. Bullard ◽  
Robert Kirk DeLisle ◽  
Susan M. Keenan
Keyword(s):  
Drug Discovery ◽  
In Silico ◽  
Novel Targets

156 A cutting-edge to drug discovery in Cancer; Cyclins as novel, targets - an in silico technique

2013 ◽  
Vol 31 (sup1) ◽  
pp. 102-102
Author(s):  
P. Sarita Rajender ◽  
K. Bhargavi ◽  
D. Ramasree ◽  
V. Uma
Keyword(s):  
Drug Discovery ◽  
In Silico ◽  
Cutting Edge ◽  
Novel Targets

An advanced in silico drug discovery platform, 4HF Data Miner for identifying novel targets for tumors and tumor-stroma

2020 ◽  
Vol 138 ◽  
pp. S27
Author(s):  
S. Das ◽  
V. Vuaroqueaux ◽  
H. Al-Hasani ◽  
A.L. Peille ◽  
A. Musch ◽  
...  
Keyword(s):  
Drug Discovery ◽  
In Silico ◽  
Tumor Stroma ◽  
Novel Targets

In Silico Meets In Vitro Techniques in ADMET Profiling of Drug Discovery (Part I)

2020 ◽  
Vol 21 (10) ◽  
pp. 745-745
Author(s):  
Supratik Kar ◽  
Sagnik Chatterjee
Keyword(s):  
Drug Discovery ◽  
In Silico ◽  
In Vitro Techniques

scholarly journals Targeting the SARS-CoV-2 main protease using FDA-approved Isavuconazonium, a P2–P3 α-ketoamide derivative and Pentagastrin: An in-silico drug discovery approach

2020 ◽  
Vol 101 ◽  
pp. 107730 ◽  
Author(s):  
Ikechukwu Achilonu ◽  
Emmanuel Amarachi Iwuchukwu ◽  
Okechinyere Juliet Achilonu ◽  
Manuel Antonio Fernandes ◽  
Yasien Sayed
Keyword(s):  
Drug Discovery ◽  
In Silico ◽  
Main Protease

Predictive DMPK: In Silico ADME Predictions in Drug Discovery

2013 ◽  
Vol 10 (4) ◽  
pp. 1151-1152 ◽  
Author(s):  
Jane R. Kenny
Keyword(s):  
Drug Discovery ◽  
In Silico

scholarly journals Novel Targets and Mechanisms in Antimicrobial Drug Discovery

Antibiotics ◽  
2021 ◽  
Vol 10 (2) ◽  
pp. 141
Author(s):  
Donatella Tondi
Keyword(s):  
Drug Discovery ◽  
Human Health ◽  
Antimicrobial Drug ◽  
Novel Targets

The spread of infections resistant to available anti-infective drugs is a serious menace to human health [...]

Deployment of in silico and in vitro safety assays in early-stage drug discovery

2012 ◽  
Vol 4 (10) ◽  
pp. 1211-1213 ◽  
Author(s):  
Yvonne Will ◽  
Thomas Schroeter
Keyword(s):  
Drug Discovery ◽  
In Silico ◽  
Early Stage

Screening of phytochemicals from Curcuma longa for their inhibitory activity on SARS-CoV-2: An in-silico study

2021 ◽  
Vol 19 ◽  
Author(s):  
Preeya Negi ◽  
Lalita Das ◽  
Surya Prakash ◽  
Vaishali M. Patil
Keyword(s):  
Drug Discovery ◽  
In Silico ◽  
Curcuma Longa ◽  
Docking Studies ◽  
Primary Objective ◽  
In Silico Screening ◽  
Rational Drug ◽  
In Silico Study ◽  
Speed Up ◽  
Novel Coronavirus

Introduction: Natural products or phytochemicals have always been useful as effective therapeutics and for providing the lead for rational drug discovery approaches specific to anti-viral therapeutics. Methods: The ongoing pandemic caused by novel coronavirus has created a demand for effective therapeutics. Thus, to achieve the primary objective to search for effective anti-viral therapeutics, in silico screening of phytochemicals present in Curcuma longa extract (ex. Curcumin) has been planned. Results: The present work involves the evaluation of ADME properties and molecular docking studies. Conclusion: The application of rationalized drug discovery approaches to screen the diverse natural resources will speed up the anti-COVID drug discovery efforts and benefit the global community.

Sign in / Sign up

Export Citation Format

Share Document