Therapeutic Implications of Heat Shock Proteins in Cancer

2019 ◽  
pp. 211-243 ◽  
Author(s):  
Maxim Shevtsov ◽  
Gabriele Multhoff
Keyword(s):  
Heat Shock ◽  
Heat Shock Proteins ◽  
Therapeutic Implications ◽  
Shock Proteins

scholarly journals Heat Shock Proteins: Pathogenic Role in Atherosclerosis and Potential Therapeutic Implications

2012 ◽  
Vol 2012 ◽  
pp. 1-9 ◽  
Author(s):  
Arman Kilic ◽  
Kaushik Mandal
Keyword(s):  
Heat Shock ◽  
Heat Shock Proteins ◽  
Vascular Endothelial Cell ◽  
Vascular Wall ◽  
Protective Role ◽  
Therapeutic Implications ◽  
Endothelial Cell Surface ◽  
Disease States ◽  
Shock Proteins ◽  
And Function

Heat shock proteins (HSPs) are a highly conserved group of proteins that are constitutively expressed and function as molecular chaperones, aiding in protein folding and preventing the accumulation of misfolded proteins. In the arterial wall, HSPs have a protective role under normal physiologic conditions. In disease states, however, HSPs expressed on the vascular endothelial cell surface can act as targets for detrimental autoimmunity due to their highly conserved sequences. Developing therapeutic strategies for atherosclerosis based on HSPs is challenged by the need to balance such physiologic and pathologic roles of these proteins. This paper summarizes the role of HSPs in normal vascular wall processes as well as in the development and progression of atherosclerosis. The potential implications of HSPs in clinical therapies for atherosclerosis are also discussed.

Heat shock proteins in neurodegenerative diseases: Pathogenic roles and therapeutic implications

2009 ◽  
Vol 25 (8) ◽  
pp. 647-654 ◽  
Author(s):  
Hiroaki Adachi ◽  
Masahisa Katsuno ◽  
Masahiro Waza ◽  
Makoto Minamiyama ◽  
Fumiaki Tanaka ◽  
...  
Keyword(s):  
Heat Shock ◽  
Heat Shock Proteins ◽  
Neurodegenerative Diseases ◽  
Therapeutic Implications ◽  
Shock Proteins

Two Novel Agents Boost Heat Shock Proteins

2005 ◽  
Vol 36 (10) ◽  
pp. 14
Author(s):  
PATRICE WENDLING
Keyword(s):  
Heat Shock ◽  
Heat Shock Proteins ◽  
Novel Agents ◽  
Shock Proteins

Heat shock proteins in willow (Salix viminalis)

1990 ◽  
Vol 80 (2) ◽  
pp. 301-306
Author(s):  
Tiina Vahala ◽  
Tage Eriksson ◽  
Peter Engstrom
Keyword(s):  
Heat Shock ◽  
Heat Shock Proteins ◽  
Salix Viminalis ◽  
Shock Proteins
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