Morphogenesis, Genetic Stability, and Secondary Metabolite Production in Untransformed and Transformed Cultures

2020 ◽  
pp. 663-722
Author(s):  
Mihir Halder ◽  
Sumita Jha
Keyword(s):  
Secondary Metabolite ◽  
Genetic Stability ◽  
Secondary Metabolite Production ◽  
Metabolite Production ◽  
Transformed Cultures

scholarly journals Efficient direct shoot organogenesis, genetic stability and secondary metabolite production of micropropagated Digitalis purpurea L.

2018 ◽  
Vol 116 ◽  
pp. 259-266 ◽  
Author(s):  
Naivy Pérez-Alonso ◽  
Randel Martín ◽  
Alina Capote ◽  
Anabel Pérez ◽  
Elizabeth Kairúz Hernández-Díaz ◽  
...  
Keyword(s):  
Secondary Metabolite ◽  
Genetic Stability ◽  
Shoot Organogenesis ◽  
Secondary Metabolite Production ◽  
Metabolite Production ◽  
Digitalis Purpurea ◽  
Direct Shoot Organogenesis ◽  
Direct Shoot

scholarly journals The impact of bZIP Atf1ortholog global regulators in fungi

2021 ◽  
Author(s):  
Éva Leiter ◽  
Tamás Emri ◽  
Klaudia Pákozdi ◽  
László Hornok ◽  
István Pócsi
Keyword(s):  
Transcription Factors ◽  
Stress Response ◽  
Secondary Metabolite ◽  
Plant Pathogens ◽  
Leucine Zipper ◽  
Secondary Metabolite Production ◽  
Special Focus ◽  
Human Pathogens ◽  
Metabolite Production ◽  
The Impact

Abstract Regulation of signal transduction pathways is crucial for the maintenance of cellular homeostasis and organismal development in fungi. Transcription factors are key elements of this regulatory network. The basic-region leucine zipper (bZIP) domain of the bZIP-type transcription factors is responsible for DNA binding while their leucine zipper structural motifs are suitable for dimerization with each other facilitiating the formation of homodimeric or heterodimeric bZIP proteins. This review highlights recent knowledge on the function of fungal orthologs of the Schizosaccharomyces pombe Atf1, Aspergillus nidulans AtfA, and Fusarium verticillioides FvAtfA, bZIP-type transcription factors with a special focus on pathogenic species. We demonstrate that fungal Atf1-AtfA-FvAtfA orthologs play an important role in vegetative growth, sexual and asexual development, stress response, secondary metabolite production, and virulence both in human pathogens, including Aspergillus fumigatus, Mucor circinelloides, Penicillium marneffei, and Cryptococcus neoformans and plant pathogens, like Fusarium ssp., Magnaporthe oryzae, Claviceps purpurea, Botrytis cinerea, and Verticillium dahliae. Key points • Atf1 orthologs play crucial role in the growth and development of fungi. • Atf1 orthologs orchestrate environmental stress response of fungi. • Secondary metabolite production and virulence are coordinated by Atf1 orthologs.

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