How to Look at a Renal Biopsy Specimen: Preliminary Study

2020 ◽  
pp. 19-26
Author(s):  
Alexander J. Howie
Keyword(s):  
Renal Biopsy ◽  
Biopsy Specimen ◽  
Renal Biopsy Specimen ◽  
Preliminary Study

scholarly journals MPGN Type 3 Associated with Pemphigus Herpetiformis Mimicking PGNMID and Dermatitis Herpetiformis

2019 ◽  
Vol 9 (1) ◽  
pp. 15-24
Author(s):  
Yoshio Shimizu ◽  
Keiichi Wakabayashi ◽  
Yoko Hayashi ◽  
Kazuaki Hara ◽  
Rumi Aoyama ◽  
...  
Keyword(s):  
Electron Microscopy ◽  
Renal Biopsy ◽  
Biopsy Specimen ◽  
Dermatitis Herpetiformis ◽  
Complex Type ◽  
Renal Abnormality ◽  
Renal Disorder ◽  
Renal Biopsy Specimen ◽  
Blistering Disease ◽  
Type 3

A 45-year-old man suffering from dermal blistering disease with proteinuria and hematuria underwent renal biopsy. The renal biopsy specimen suggested proliferative glomerulonephritis with monoclonal IgG deposits under routine light, immunofluorescence and electron microscopy. The staining for IgG subclasses (IgG1 and IgG2) and κ/λ light chain indicated secondary immune complex type MPGN type 3. The patient had been diagnosed as having dermatitis herpetiformis (DH), a phenotype of gluten hypersensitivity prior to the appearance of the renal abnormality. Although common autoantibodies might be related to the pathogenesis of disorders in the skin and kidney, DH is mainly driven by IgA autoantibody, while MPGN is induced by IgG immune complexes. IgA was not observed in the glomeruli by immunofluorescence. Neither the examination for DH specific autoantibodies nor HLA-DQB1 genotype supported the diagnosis of DH. Reassessment of the skin biopsy record revealed that the blister was localized in the epidermis, suggesting pemphigus herpetiformis by IgG class anti-epidermal autoantibody, which also affected the renal disorder.

Incidental detection of oncocytosis in a renal biopsy specimen for idiopathic nephrotic syndrome

2011 ◽  
Vol 207 (11) ◽  
pp. 733-736 ◽  
Author(s):  
J. Fernando Val-Bernal ◽  
Emilio Rodrigo ◽  
Jorge Ruiz-Criado ◽  
M. Francisca Garijo ◽  
Josefina Martín-Gago ◽  
...  
Keyword(s):  
Nephrotic Syndrome ◽  
Renal Biopsy ◽  
Biopsy Specimen ◽  
Idiopathic Nephrotic Syndrome ◽  
Renal Biopsy Specimen

scholarly journals Unexpected Identification of Trophreyma whippelii in a Renal Biopsy Specimen

2010 ◽  
Vol 16 (S2) ◽  
pp. 1128-1129
Author(s):  
MP Goheen ◽  
SM Bonsib ◽  
CL Phillips
Keyword(s):  
Renal Biopsy ◽  
Biopsy Specimen ◽  
Renal Biopsy Specimen

Extended abstract of a paper presented at Microscopy and Microanalysis 2010 in Portland, Oregon, USA, August 1 – August 5, 2010.

scholarly journals MORPHOLOGIC EVALUATION AND INTEGRIN EXPRESSION PROFILE OF RENAL TUBULAR CELLS CULTURED FROM PERCUTANEOUS RENAL BIOPSY SPECIMEN

Renal Failure ◽  
2001 ◽  
Vol 23 (1) ◽  
pp. 21-29 ◽  
Author(s):  
Jung Sim Kim ◽  
Hye Zin Hwang ◽  
Sung Hee Yeo ◽  
Shi Whan Ko ◽  
Seng Mi Song ◽  
...  
Keyword(s):  
Renal Biopsy ◽  
Expression Profile ◽  
Biopsy Specimen ◽  
Integrin Expression ◽  
Renal Biopsy Specimen ◽  
Tubular Cells ◽  
Renal Tubular Cells ◽  
Percutaneous Renal Biopsy ◽  
Renal Tubular ◽  
Cells Cultured
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