Nanofiber Extracellular Matrices in Regenerative Medicine

Clinical applications of decellularized extracellular matrices for tissue engineering and regenerative medicine

Biomedical Materials ◽

10.1088/1748-6041/11/2/022003 ◽

2016 ◽

Vol 11 (2) ◽

pp. 022003 ◽

Cited By ~ 96

Author(s):

Mahmut Parmaksiz ◽

Arin Dogan ◽

Sedat Odabas ◽

A Eser Elçin ◽

Y Murat Elçin

Keyword(s):

Tissue Engineering ◽

Regenerative Medicine ◽

Clinical Applications ◽

Extracellular Matrices ◽

Matrices For Tissue Engineering

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Design of Artificial Extracellular Matrices and Their Application for Regenerative Medicine

Biomaterials in Asia ◽

10.1142/9789812835758_0009 ◽

2008 ◽

Author(s):

Xiaoshan Yue ◽

Masato Nagaoka ◽

Akaike Toshihiro

Keyword(s):

Regenerative Medicine ◽

Extracellular Matrices

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Distribution of VLA-5 and VLA-4 fibronectin receptors in human monocytes demonstrated by immunofluorescence, immunocytochemistry, and autoradiography

Proceedings, annual meeting, Electron Microscopy Society of America ◽

10.1017/s0424820100147375 ◽

1993 ◽

Vol 51 ◽

pp. 306-307

Author(s):

Robert Williams ◽

Che-Hung Lee ◽

Sara E. Quella ◽

David M. Harlan ◽

Yuan-Hsu Kang

Keyword(s):

Present Report ◽

Matrix Proteins ◽

Extracellular Matrices ◽

Human Monocytes ◽

Integrin Receptors ◽

Morphological Evaluation ◽

The Matrix ◽

Specific Receptors ◽

Cytokine Stimulation ◽

Monocyte Adherence

Monocyte adherence to endothelial or extracellular matrices plays an important role in triggering monocyte activation in extravascular sites of infection, chronic inflammatory disorders, and tissue damage. Migration of monocytes in the tissues involves the response to a chemoattractant and movement by a series of attachments and detachments to the extracellular matrices which are regulated by expression and distribution of specific receptors for the matrix proteins such as fibronectin (FN). The VSAs (very late antigens or beta integrins), a subfamily of the transmembrane heterodimeric integrin receptors, have been thought to play a major role in monocyte adherence to the extracellular matrices and cells. In this subfamily, VLA-5 and VLA-4 are believed to be the most essential integrins mediating monocyte adherence to FN. In the present report, we have established and compared different procedures for morphological evaluation of the expression and distribution of the FN receptors on human monocytes in order to investigate their response to endotoxin or cytokine stimulation.

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