Mesenchymal stem cells secretome: a new therapeutic tool for Parkinson’s disease regenerative medicine?

2017 ◽  
Author(s):  
Bárbara Pinheiro
Keyword(s):  
Parkinson’S Disease ◽  
Stem Cells ◽  
Parkinson's Disease ◽  
Mesenchymal Stem Cells ◽  
Regenerative Medicine ◽  
Therapeutic Tool

Mesenchymal stem cells secretome: a new therapeutic tool for Parkinson’s disease regenerative medicine?

2017 ◽  
Vol 27 ◽  
pp. S687-S688 ◽  
Author(s):  
B. Mendes-Pinheiro ◽  
F.G. Teixeira ◽  
S. Anjo ◽  
B. Manadas ◽  
L. Behie ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Stem Cells ◽  
Parkinson's Disease ◽  
Mesenchymal Stem Cells ◽  
Regenerative Medicine ◽  
Therapeutic Tool

Intranasal administration of endometrial mesenchymal stem cells as a suitable approach for Parkinson’s disease therapy

2019 ◽  
Vol 46 (4) ◽  
pp. 4293-4302 ◽  
Author(s):  
Saeid Bagheri-Mohammadi ◽  
Behrang Alani ◽  
Mohammad Karimian ◽  
Rana Moradian-Tehrani ◽  
Mahdi Noureddini
Keyword(s):  
Parkinson’S Disease ◽  
Stem Cells ◽  
Parkinson's Disease ◽  
Mesenchymal Stem Cells ◽  
Intranasal Administration ◽  
Disease Therapy

Therapeutic benefit of TH-engineered mesenchymal stem cells for Parkinson's disease

2005 ◽  
Vol 15 (1) ◽  
pp. 46-51 ◽  
Author(s):  
Lingling Lu ◽  
Chunli Zhao ◽  
Yujun Liu ◽  
Xiaohong Sun ◽  
Chunli Duan ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Stem Cells ◽  
Parkinson's Disease ◽  
Mesenchymal Stem Cells ◽  
Therapeutic Benefit

Partial recovery of dopaminergic pathway after graft of adult mesenchymal stem cells in a rat model of Parkinson's disease

2008 ◽  
Vol 52 (7) ◽  
pp. 1332-1342 ◽  
Author(s):  
Gaëlle Bouchez ◽  
Luc Sensebé ◽  
Patrick Vourc’h ◽  
Lucette Garreau ◽  
Sylvie Bodard ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Stem Cells ◽  
Parkinson's Disease ◽  
Mesenchymal Stem Cells ◽  
Rat Model ◽  
Partial Recovery ◽  
Dopaminergic Pathway ◽  
Adult Mesenchymal Stem Cells

Neuroprotective effect of bone marrow derived mesenchymal stem cell secretome in 6-OHDA-induced Parkinson's disease

2021 ◽  
Author(s):  
Dhruv Mahendru ◽  
Ashish Jain ◽  
Seema Bansal ◽  
Deepti Malik ◽  
Neha Dhir ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Stem Cells ◽  
Bone Marrow ◽  
Parkinson's Disease ◽  
Mesenchymal Stem Cells ◽  
Stem Cell ◽  
Neuroprotective Effect ◽  
Behavioral Parameters ◽  
Old Rats ◽  
6 Hydroxydopamine

Aim: The aim of the study was to evaluate the neuroprotective effect of bone marrow stem cell secretome in the 6-hydroxydopamine (6-OHDA) model of Parkinson's disease. Materials & methods: Secretome prepared from mesenchymal stem cells of 3-month-old rats was injected daily for 7 days between days 7 and 14 after 6-OHDA administration. After 14 days, various neurobehavioral parameters were conducted. These behavioral parameters were further correlated with biochemical and molecular findings. Results & conclusion: Impaired neurobehavioral parameters and increased inflammatory, oxidative stress and apoptotic markers in the 6-OHDA group were significantly modulated by secretome-treated rats. In conclusion, mesenchymal stem cells-derived secretome could be further explored for the management of Parkinson's disease.

scholarly journals Updates in the pathophysiological mechanisms of Parkinson’s disease: Emerging role of bone marrow mesenchymal stem cells

2016 ◽  
Vol 8 (3) ◽  
pp. 106 ◽  
Author(s):  
Hanaa H Ahmed ◽  
Ahmed M Salem ◽  
Hazem M Atta ◽  
Emad F Eskandar ◽  
Abdel Razik H Farrag ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Stem Cells ◽  
Bone Marrow ◽  
Parkinson's Disease ◽  
Mesenchymal Stem Cells ◽  
Pathophysiological Mechanisms ◽  
Marrow Mesenchymal Stem Cells

scholarly journals Synergistic effect of electric stimulation and mesenchymal stem cells against Parkinson's disease

Aging ◽  
2020 ◽  
Vol 12 (16) ◽  
pp. 16062-16071
Author(s):  
Chunhui Yang ◽  
Yiqing Qiu ◽  
Yuan Qing ◽  
Jinyu Xu ◽  
Wei Dai ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Stem Cells ◽  
Parkinson's Disease ◽  
Mesenchymal Stem Cells ◽  
Synergistic Effect ◽  
Electric Stimulation

Stem cell-based therapy for Parkinson’s disease with a focus on human endometrium-derived mesenchymal stem cells

2018 ◽  
Vol 234 (2) ◽  
pp. 1326-1335 ◽  
Author(s):  
Saeid Bagheri-Mohammadi ◽  
Mohammad Karimian ◽  
Behrang Alani ◽  
Javad Verdi ◽  
Rana Moradian Tehrani ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Stem Cells ◽  
Parkinson's Disease ◽  
Mesenchymal Stem Cells ◽  
Stem Cell ◽  
Human Endometrium ◽  
Cell Based Therapy
Sign in / Sign up

Export Citation Format

Share Document