Clinical Case Debate: Neoadjuvant Checkpoint Inhibition Versus Standard Chemotherapy

2022 ◽  
pp. 13-25
Author(s):  
Marco Bandini ◽  
Giuseppe Basile ◽  
Andrea Gallina
Keyword(s):  
Clinical Case ◽  
Checkpoint Inhibition ◽  
Standard Chemotherapy

scholarly journals Successful treatment of a chemo-resistant gestational trophoblastic neoplasia using GEMOX. Clinical case

2020 ◽  
Vol 25 (1) ◽  
pp. 42-46
Author(s):  
A. A. Meshcheryakov ◽  
T. E. Tikhomirova ◽  
L. A. Meshcheryakova
Keyword(s):  
Successful Treatment ◽  
Clinical Case ◽  
Treatment Approach ◽  
Multidrug Resistant ◽  
Gestational Trophoblastic Neoplasia ◽  
Standard Chemotherapy ◽  
Adequate Treatment ◽  
Rare Malignancy ◽  
Almost All

Gestational trophoblastic neoplasia is a rare malignancy. The main treatment approach is chemotherapy. Almost all patients can be cured if the diagnosis is established timely and adequate treatment is provided in specialized centers. In a small part of patients, the tumor progresses despite the use of all standard chemotherapy regimens. Treatment of such patients is difficult for all oncologists, including ones working in specialized centers for the treatment of gestational trophoblastic neoplasia. This article presents a clinical case of the successful treatment of a patient with multidrug resistant gestational trophoblastic neoplasia using GEMOX regimen.

Endocrinopathies related to immune checkpoint inhibition: A clinical case presentation

2020 ◽  
Author(s):  
David Veríssimo ◽  
de Castro Matilde Jácome ◽  
Catarina Ivo ◽  
Vitória Duarte ◽  
Mafalda Marcelino ◽  
...  
Keyword(s):  
Immune Checkpoint ◽  
Clinical Case ◽  
Checkpoint Inhibition ◽  
Immune Checkpoint Inhibition ◽  
Case Presentation

scholarly journals Successful treatment of high-risk gestational trophoblastic disease in a patient with intolerance to standard chemotherapy (clinical case)

2021 ◽  
Vol 16 (3) ◽  
pp. 67-71
Author(s):  
G. M. Teletaeva ◽  
E. A. Ulrikh ◽  
D. Kh. Latipova ◽  
A. I. Semenova ◽  
E. V. Levchenko ◽  
...  
Keyword(s):  
High Risk ◽  
Clinical Case ◽  
Risk Group ◽  
Gestational Trophoblastic Disease ◽  
High Risk Group ◽  
Standard Chemotherapy ◽  
Trophoblastic Disease ◽  
Highly Sensitive ◽  
Drug Doses ◽  
Systemic Drug

Gestational trophoblastic disease is a rare tumor highly sensitive to systemic drug therapy. The standard regimens of chemotherapy of I and II lines for patients in the high-risk group for gestational trophoblastic disease are the EMA-CO, EMA-EP and TP/TE regimens, which have been demonstrated to be effective and require adherence to drug doses and intervals of administration. If these criteria are not met, the risk of developing resistance with an unfavorable outcome for patients is extremely high. The situation is extremely difficult when a patient has an absolute allergic intolerance to one of the components of standard regimens, which is presented in a clinical case.

The Variable Nature of Stuttering: A Clinical Case Study

1995 ◽  
Vol 22 ◽  
pp. 29-35
Author(s):  
Jennifer Gutierrez ◽  
Anthony Caruso
Keyword(s):  
Clinical Case ◽  
Clinical Case Study ◽  
Variable Nature

Abstract #522: Calcitirol Mediated Hypercalcemia in A Patient with Silicone Granulomas dueto Cosmetic Injections: Clinical Case

2015 ◽  
Vol 21 ◽  
pp. 108-109
Author(s):  
Ana Abaroa-Salvatierra ◽  
Arti Patel ◽  
Mrunalini Deshmukh
Keyword(s):  
Clinical Case

Case Formulation and Design of Behavioral Treatment Programs

2003 ◽  
Vol 19 (3) ◽  
pp. 164-174 ◽  
Author(s):  
Stephen N. Haynes ◽  
Andrew E. Williams
Keyword(s):  
Functional Analysis ◽  
Behavior Problems ◽  
Behavioral Treatment ◽  
Clinical Case ◽  
Relative Magnitude ◽  
Mechanisms Of Action ◽  
Treatment Programs ◽  
Case Formulation ◽  
Functional Relations ◽  
Causal Variables

Summary: We review the rationale for behavioral clinical case formulations and emphasize the role of the functional analysis in the design of individualized treatments. Standardized treatments may not be optimally effective for clients who have multiple behavior problems. These problems can affect each other in complex ways and each behavior problem can be influenced by multiple, interacting causal variables. The mechanisms of action of standardized treatments may not always address the most important causal variables for a client's behavior problems. The functional analysis integrates judgments about the client's behavior problems, important causal variables, and functional relations among variables. The functional analysis aids treatment decisions by helping the clinician estimate the relative magnitude of effect of each causal variable on the client's behavior problems, so that the most effective treatments can be selected. The parameters of, and issues associated with, a functional analysis and Functional Analytic Clinical Case Models (FACCM) are illustrated with a clinical case. The task of selecting the best treatment for a client is complicated because treatments differ in their level of specificity and have unequally weighted mechanisms of action. Further, a treatment's mechanism of action is often unknown.

The Instrumentalization of Action: A Plan for Clinical Case Conceptualization

1997 ◽  
Vol 42 (6) ◽  
pp. 532-532
Author(s):  
Robert L. Russell
Keyword(s):  
Clinical Case ◽  
Case Conceptualization

1994 Clinical Case Conference: Coping with Ritual Abuse Reports

1995 ◽  
Author(s):  
George E. Abbott ◽  
◽  
Ray William London ◽  
Irving Kirsch
Keyword(s):  
Clinical Case ◽  
Case Conference ◽  
Ritual Abuse
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