The Role of the Kininogens as Cysteine Proteinase Inhibitors in Local and Systemic Inflammation

1992 ◽  
pp. 312-321 ◽  
Author(s):  
I. Assfalg-Machleidt ◽  
A. Billing ◽  
D. Fröhlich ◽  
D. Nast-Kolb ◽  
Th. Joka ◽  
...  
1992 ◽  
Vol 3 (4) ◽  
pp. 307-332 ◽  
Author(s):  
Libuse A. Bobek ◽  
Michael J. Levine

The cystatin superfamily of proteins, derived from a common ancestor, is comprised of a diverse group of potent cysteine proteinase inhibitors and antibacterial/viral agents grouped into several families. This review concentrates on family 2 cystatins, namely, the human salivary cystatins and cystatin C. Emphasis is given to their physicochemical and functional properties at both the protein and the molecular level. The role of cystatins in disease processes, including those in the oral cavity, is also discussed. Finally, future directions for cystatin research in oral biology are presented.


2006 ◽  
Vol 50 (8) ◽  
pp. 2886-2888
Author(s):  
Salman Baig ◽  
Raymond T. Damian ◽  
Jorge Morales-Montor ◽  
Rupal Thazhath ◽  
Amr Ghaleb ◽  
...  

ABSTRACT We explored the prophylactic efficacies of two novel protease inhibitors in murine cysticercosis. Our results demonstrated a 95% and 80% reduction in parasite burden for mice injected with Z-LLL-FMK and Z-LLY-FMK, respectively. Further studies are merited on the role of cysteine proteinase inhibitors in treatment of cysticercosis.


Genomics ◽  
1993 ◽  
Vol 15 (3) ◽  
pp. 507-514 ◽  
Author(s):  
Florence W.L. Tsui ◽  
Hing-Wo Tsui ◽  
Samuel Mok ◽  
Irena Mlinaric ◽  
Neal G. Copeland ◽  
...  

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