Clinical experience of osteogenic protein-1 (OP-1) in the repair of bone defects and fractures of long bones

2004 ◽  
pp. 157-162 ◽  
Author(s):  
Gary E. Friedlaender
Keyword(s):  
Clinical Experience ◽  
Bone Defects ◽  
Long Bones ◽  
Osteogenic Protein

scholarly journals Type B Idiopathic Bone Defect of Mandible: An Etiopathogenic Dilemma

2012 ◽  
Vol 2012 ◽  
pp. 1-4
Author(s):  
Aakarsh V. Jhamb ◽  
Parul A. Jhamb ◽  
Aparna Dave ◽  
Vishwa Prakash Shetty
Keyword(s):  
Bone Defect ◽  
Type A ◽  
Bone Defects ◽  
Long Bones ◽  
Type B ◽  
Jaw Bones ◽  
Pathologic Lesions ◽  
Malignant Lesions ◽  
Radiographic Interpretation

Etiopathogenesis of the pathologic lesions forms the basis for formulation of appropriate intervention and further prevention. There is still a vast unknown field that has to be explored to know the causative reason behind certain benign & malignant lesions. Idiopathic bone defects are nonodontogenic pseudocystic cavities that are seen in the long bones & jaw bones. Radiographic interpretation is at times inadequate in diagnosis of odontogenic & nonodontogenic radiolucent lesions involving jaw bones. Histopathology has different criteria to segregate this lesion. In this paper, we discuss a case of type B histopathological variant of idiopathic bone defect that may suggest an alternative pathogenesis from type A variant.

The Effect of Osteogenic Protein-1 on the Healing of Segmental Bone Defects Treated with Autograft or Allograft Bone

2001 ◽  
Vol 83 (6) ◽  
pp. 803-816 ◽  
Author(s):  
Samantha L. Salkeld ◽  
Laura Popich Patron ◽  
Robert L. Barrack ◽  
Stephen D. Cook
Keyword(s):  
Bone Defects ◽  
Allograft Bone ◽  
Osteogenic Protein ◽  
Segmental Bone ◽  
Segmental Bone Defects

scholarly journals Local delivery of a novel PTHrPviamesoporous bioactive glass scaffolds to improve bone regeneration in a rat posterolateral spinal fusion model

RSC Advances ◽  
2018 ◽  
Vol 8 (22) ◽  
pp. 12484-12493 ◽  
Author(s):  
Bo Liang ◽  
Jinghuan Huang ◽  
Jianguang Xu ◽  
Xiaolin Li ◽  
Jingfeng Li
Keyword(s):  
Tissue Engineering ◽  
Bioactive Glass ◽  
Bone Regeneration ◽  
Spinal Fusion ◽  
Bone Substitutes ◽  
Bone Defects ◽  
Local Delivery ◽  
Long Bones ◽  
Fusion Model ◽  
Posterolateral Spinal Fusion

With the development of tissue engineering, bone defects, such as fractured long bones or cavitary lesions, may be efficiently repaired and reconstructed using bone substitutes.

scholarly journals Strategies for the analysis of osteitic bone defects at the diaphysis of long bones

2009 ◽  
Vol 4 (1) ◽  
pp. 13-18 ◽  
Author(s):  
A. H. Tiemann ◽  
H. G. K. Schmidt ◽  
R. Braunschweig ◽  
G. O. Hofmann
Keyword(s):  
Bone Defects ◽  
Long Bones

Surgical repair of long bone defects or trauma by guided tissue engineering with composite implants of porous bioactive glass-ceramic (A-WGC) particles bound by a plaster/CaO/P2O5 cement contained by a resorbable vicryl™ mesh

1995 ◽  
Vol 53 ◽  
pp. 800-801
Author(s):  
J.S. Hanker ◽  
L.C. Hanker ◽  
B.L. Giammara
Keyword(s):  
Orthopedic Surgery ◽  
Bone Repair ◽  
Surgical Repair ◽  
Bone Defects ◽  
The Body ◽  
Long Bone ◽  
Trauma Patients ◽  
Long Bones ◽  
Bone Trauma ◽  
Guided Tissue Engineering

One of the biggest problems associated with the repair of trauma in long bones is their requirement to withstand greater mechanical stress than any other bones of the body. After the success we achieved with composite hydroxylapatite (HA)/plaster(PP) in craniofacial bone repair in approximately 200 animals (cats and rats) and 300 humans in our laboratory, clinics and surgeries, it was felt that an area which could perhaps benefit from our experience in bone repair might be orthopedic surgery. When first informed of our desire to apply our biomaterials interest and experience to long bone trauma patients, others expected little success with these biomaterials that were so successful in craniofacial surgery.We felt, however, that success might be achieved for long bone repair with plaster of Paris (CaSO4·½H2O) and/or calcium phosphate. The feeling of my laboratory received some support from Larry Hench's 1988 article. In this article he pointed out that bioactive ceramics such as hydroxylapatite (HA) possibly could bond to bone.

The effect of recombinant human osteogenic protein-1 on healing of large segmental bone defects.

1994 ◽  
Vol 76 (6) ◽  
pp. 827-838 ◽  
Author(s):  
S D Cook ◽  
G C Baffes ◽  
M W Wolfe ◽  
T K Sampath ◽  
D C Rueger ◽  
...  
Keyword(s):  
Bone Defects ◽  
Osteogenic Protein ◽  
Segmental Bone ◽  
Segmental Bone Defects
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