Identification, localization and function of muscarinic receptor subtypes in the airways

2001 ◽  
pp. 63-85 ◽  
Author(s):  
Ad F. Roffel ◽  
Herman Meurs ◽  
Johan Zaagsma
Keyword(s):  
Muscarinic Receptor ◽  
Receptor Subtypes ◽  
Muscarinic Receptor Subtypes ◽  
And Function

Primary cultures of corticostriatal cells from newborn rats: A model to study muscarinic receptor subtypes regulation and function

1990 ◽  
Vol 2 (3) ◽  
pp. 143-153 ◽  
Author(s):  
Carola Eva ◽  
Patrizia Bovolin ◽  
Fiorella Balzac ◽  
Cristina Botta ◽  
Silvana Ricci Gamalero ◽  
...  
Keyword(s):  
Muscarinic Receptor ◽  
Primary Cultures ◽  
Receptor Subtypes ◽  
Muscarinic Receptor Subtypes ◽  
Newborn Rats ◽  
And Function

In Vivo Characterization of Muscarinic Receptor Subtypes That Mediate Vasodilatation in Patients With Essential Hypertension

Hypertension ◽  
1995 ◽  
Vol 26 (1) ◽  
pp. 70-77 ◽  
Author(s):  
Tobias A. Bruning ◽  
Peter C. Chang ◽  
Maarten G.C. Hendriks ◽  
Pieter Vermeij ◽  
Martin Pfaffendorf ◽  
...  
Keyword(s):  
Essential Hypertension ◽  
Muscarinic Receptor ◽  
Receptor Subtypes ◽  
Muscarinic Receptor Subtypes ◽  
In Vivo Characterization

Differential regulation of PI hydrolysis and adenylyl cyclase by muscarinic receptor subtypes

Nature ◽  
1988 ◽  
Vol 334 (6181) ◽  
pp. 434-437 ◽  
Author(s):  
Ernest G. Peralta ◽  
Avi Ashkenazi ◽  
John W. Winslow ◽  
J. Ramachandran ◽  
Daniel J. Capon
Keyword(s):  
Adenylyl Cyclase ◽  
Muscarinic Receptor ◽  
Differential Regulation ◽  
Receptor Subtypes ◽  
Muscarinic Receptor Subtypes ◽  
Pi Hydrolysis

Pre- and postjunctional muscarinic receptor subtypes in the vas deferens of rat

1994 ◽  
Vol 25 (8) ◽  
pp. 1643-1647 ◽  
Author(s):  
H.F. Miranda ◽  
E. Duran ◽  
D. Bustamante ◽  
C. Paeile ◽  
G. Pinardi
Keyword(s):  
Muscarinic Receptor ◽  
Vas Deferens ◽  
Receptor Subtypes ◽  
Muscarinic Receptor Subtypes

Location and quantification of muscarinic receptor subtypes in rat pons: implications for REM sleep generation

1997 ◽  
Vol 273 (3) ◽  
pp. R896-R904 ◽  
Author(s):  
H. A. Baghdoyan
Keyword(s):  
Muscarinic Receptor ◽  
Reticular Formation ◽  
Muscarinic Receptors ◽  
Rem Sleep ◽  
Binding Sites ◽  
Reticular Nucleus ◽  
Homogeneous Distribution ◽  
Receptor Subtypes ◽  
Pontine Reticular Formation ◽  
Muscarinic Receptor Subtypes

Microinjecting cholinomimetics into the pontine reticular formation produces a state that resembles natural rapid eye movement (REM) sleep. Evocation of this REM sleeplike states is anatomically site dependent within the pons and is mediated by muscarinic receptors. The cellular and molecular mechanisms underlying cholinergic REM sleep generation and muscarinic receptor subtype involvement remain to be specified. This study tested the hypothesis that muscarinic receptor subtypes are differentially distributed within the oral and caudal divisions of rat pontine reticular nucleus. In vitro receptor autoradiography was used to localize and quantify M1, M2, and M3 binding sites in the pontine reticular formation and in pontine brain stem regions known to regulate REM sleep. M1-M3 binding sites were present in some REM sleep-related nuclei, such as dorsal raphe and locus ceruleus. The pontine reticular formation was found to have a homogeneous distribution of M2 binding sites across its rostral to caudal extent, indicating that anatomic specificity of cholinergic REM sleep induction cannot be accounted for by a differential density of muscarinic receptors.

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