Laboratory Medicine: Reference Values and Evidence-Based Medicine

Neonatology ◽  
2018 ◽  
pp. 2429-2432
Author(s):  
Mariangela Longini ◽  
Fabrizio Proietti ◽  
Francesco Bazzini ◽  
Elisa Belvisi
Keyword(s):  
Reference Values ◽  
Evidence Based Medicine ◽  
Laboratory Medicine ◽  
Evidence Based ◽  
Based Medicine

Laboratory Medicine: Reference Values and Evidence-Based Medicine

Neonatology ◽  
2016 ◽  
pp. 1-3
Author(s):  
Mariangela Longini ◽  
Fabrizio Proietti ◽  
Francesco Bazzini ◽  
Elisa Belvisi
Keyword(s):  
Reference Values ◽  
Evidence Based Medicine ◽  
Laboratory Medicine ◽  
Evidence Based ◽  
Based Medicine

scholarly journals The role of evidence-based laboratory medicine in health service

2002 ◽  
Vol 21 (3) ◽  
pp. 245-254 ◽  
Author(s):  
Nada Majkic-Singh
Keyword(s):  
Health Care ◽  
Clinical Experience ◽  
Evidence Based Medicine ◽  
Laboratory Tests ◽  
Laboratory Medicine ◽  
Systematic Research ◽  
Evidence Based ◽  
External Evidence ◽  
Based Medicine ◽  
The Impact

Evidence-based laboratory medicine (EBLM) is the use of the current best evidence of the utility of laboratory tests in making decisions about the care of individual patients. This practice means integrating laboratory and clinical experience with the last available external evidence from systematic research. It means that the definition of EBLM focuses on two key elements: experience and evidence from systematic research. Although the term evidence-based medicine (EBM) was created in Canada at Mc Master University by a group lad by Dr Gard Guyatt, there are various claims as to the origin of its practice. Regardless of its origins, many factors have come together over the past 30 years to drive the movement to EBM. One factor is those individual physicians, faced with numerous medical informations; the second factor is the global phenomenon of increasing health care costs and third is that patients who have generally more education, want the best in diagnostics and therapies. It means that evidence-based medicine has been driven by the need to cape with information overload, by costcontrol, and by public impatient for the best in diagnostics and treatment. Clinical guidelines care maps, and outcome measures are quality improvement tools for the appropriateness, efficiency and effectiveness of health services. Laboratory professionals must direct more effort to demonstrating the impact of laboratory tests on a greater variety of clinical outcomes. Evidence-based laboratory medicine aims to advise clinical diagnosis and management of disease through systematic researching and disseminating generalisible new knowledge that meets the standard of critical review on clinically effective practice of laboratory investigations. In laboratory medicine, the use of tests increases; new tests are constantly introduced, but "old" tests are seldom removed from the repertoire. This, together with limited public funds for the health care should underline the challenge for laboratory professionals to provide evidence for the utility of different tests. This practice means integrating laboratory and clinical experience with the best available external evidence from systematic research therefore, it is important that advice given by laboratory medicine professionals are sound and based on evidence in the pre-analytical, analytical, and post-analytical phases of the diagnostic process. This paper provides an insight into the rationale, methodology and the phases of the EBLM.

scholarly journals Overview of Evidence-based Medicine: Challenges for Evidence-based Laboratory Medicine

2001 ◽  
Vol 47 (8) ◽  
pp. 1536-1546 ◽  
Author(s):  
Matthew J McQueen
Keyword(s):  
Evidence Based Medicine ◽  
Information Overload ◽  
Clinical Information ◽  
Laboratory Medicine ◽  
Evidence Based ◽  
Efficiency And Effectiveness ◽  
Care Maps ◽  
Critical Appraisal Skills ◽  
Based Medicine ◽  
The Impact

Abstract Evidence-based medicine (EBM) has been driven by the need to cope with information overload, by cost-control, and by a public impatient for the best in diagnostics and treatment. Clinical guidelines, care maps, and outcome measures are quality improvement tools for the appropriateness, efficiency, and effectiveness of health services. Although they are imperfect, their value increases with the quality of the evidence they incorporate. Laboratory professionals must direct more effort to demonstrating the impact of laboratory tests on a greater variety of clinical outcomes. Laboratory and clinical practitioners must be familiar with many of the accessible electronic and paper tools for searching for evidence. Detailed statistical and epidemiologic knowledge is not essential, but critical appraisal skills and a competent understanding of the strengths and weaknesses of systematic review and metaanalysis are necessary. Overemphasis on complexity and failure to recognize time limitations are major barriers to translating EBM into everyday practice. Emphasizing and practicing the role of the laboratory professional as a skilled clinical consultant strongly grounded in evidence as well, in addition to better integration of laboratory and clinical information and improved laboratory reports will overcome most barriers. There is a poverty of good, primary studies of test evaluations. Institution of more consistent standards for the design and reporting of studies on diagnostic accuracy should improve the situation. If nothing else, systematic reviews have demonstrated the need for more good-quality primary research in laboratory medicine.

Applying evidence based medicine in laboratory medicine: A pilot study

2019 ◽  
Vol 493 ◽  
pp. S349
Author(s):  
N. Giménez ◽  
D. Morell-García ◽  
J.A. Allué ◽  
M.D. Albadalejo ◽  
M.A. Castaño ◽  
...  
Keyword(s):  
Pilot Study ◽  
Evidence Based Medicine ◽  
Laboratory Medicine ◽  
Evidence Based ◽  
Based Medicine

Evidence-Based Principles in Pathology: Existing Problem Areas and the Development of “Quality” Practice Patterns

2011 ◽  
Vol 135 (11) ◽  
pp. 1398-1404 ◽  
Author(s):  
Mark R. Wick ◽  
Alberto M. Marchevsky
Keyword(s):  
Evidence Based Medicine ◽  
English Literature ◽  
Clinical Pathology ◽  
Laboratory Medicine ◽  
Evidence Based ◽  
Quality Practices ◽  
Laboratory Services ◽  
Cost Of Health Care ◽  
Hepatic Iron Overload ◽  
Based Medicine

Context.—Contrary to the intuitive impressions of many pathologists, several areas exist in laboratory medicine where evidence-based medicine (EBM) principles are not applied. These include aspects of both anatomic and clinical pathology. Some non-EBM practices are perpetuated by clinical “consumers” of laboratory services because of inadequate education, habit, or overreliance on empirical factors. Other faulty procedures are driven by pathologists themselves. Objectives.—To consider (1) several selected problem areas representing non-EBM practices in laboratory medicine; such examples include ideas and techniques that concern metastatic malignancies, “targeted” oncologic therapy, general laboratory testing and data utilization, evaluation of selected coagulation defects, administration of blood products, and analysis of hepatic iron-overload syndromes; and (2) EBM principles as methods for remediation of deficiencies in hospital pathology, and implements for the construction of “quality” practices in our specialty. Data Sources.—Current English literature relating to evidence-based principles in pathology and laboratory medicine, as well as the authors' experience. Conclusions.—Evidence-based medicine holds the promise of optimizing laboratory services to produce “quality” practices in pathology. It will also be a key to restraining the overall cost of health care.

Evidence-based medicine

2002 ◽  
Vol 44 (07) ◽  
Author(s):  
Peter G Procopis
Keyword(s):  
Evidence Based Medicine ◽  
Evidence Based ◽  
Based Medicine
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