Paediatric Tumours

2017 ◽  
pp. 73-76
Author(s):  
Lucy Fowkes ◽  
Sue Chua
Keyword(s):  
Paediatric Tumours

scholarly journals Non-invasive distal femoral expandable endoprosthesis for limb-salvage surgery in paediatric tumours

2006 ◽  
Vol 88-B (5) ◽  
pp. 649-654 ◽  
Author(s):  
A. Gupta ◽  
J. Meswania ◽  
R. Pollock ◽  
S. R. Cannon ◽  
T. W. R. Briggs ◽  
...  
Keyword(s):  
Limb Salvage ◽  
Salvage Surgery ◽  
Limb Salvage Surgery ◽  
Paediatric Tumours ◽  
Non Invasive

Paediatric Tumours

TNM-Atlas ◽  
1985 ◽  
pp. 211-233
Author(s):  
B. Spiessl ◽  
P. Hermanek ◽  
O. Scheibe ◽  
G. Wagner
Keyword(s):  
Paediatric Tumours

General Characteristics of Paediatric Tumours

1987 ◽  
pp. 305-309
Author(s):  
S. Monfardini ◽  
K. Brunner ◽  
D. Crowther ◽  
S. Eckhardt ◽  
D. Olive ◽  
...  
Keyword(s):  
Paediatric Tumours

Principles of paediatric radiation oncology

2013 ◽  
Author(s):  
Roger E Taylor
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Hodgkin Lymphoma ◽  
Radiation Oncology ◽  
Intensity Modulated Radiotherapy ◽  
Primitive Neuroectodermal Tumour ◽  
Paediatric Tumours ◽  
Intensity Modulated ◽  
Non Hodgkin Lymphoma ◽  
Central Nervous System Tumours

Chapter 15 discusses the principles of paediatric radiation oncology, and addresses quality assurance, chemotherapy/radiotherapy interactions, Leukaemia, Hodgkin lymphoma, Non-Hodgkin lymphoma, Neuroblastoma, Rhabdomyosarcoma, Ewing’s sarcoma/peripheral primitive neuroectodermal tumour, Osteosarcoma, central nervous system tumours, Intensity-modulated radiotherapy, and proton therapy for paediatric tumours.

scholarly journals Testing algorithm for identification of patients with TRK fusion cancer

2019 ◽  
Vol 72 (7) ◽  
pp. 460-467 ◽  
Author(s):  
Frédérique Penault-Llorca ◽  
Erin R Rudzinski ◽  
Antonia R Sepulveda
Keyword(s):  
Kinase Inhibitors ◽  
System Development ◽  
In Situ Hybridisation ◽  
Nervous System Development ◽  
Diagnostic Process ◽  
Fluorescence In Situ Hybridisation ◽  
Gene Fusions ◽  
Paediatric Tumours ◽  
Testing Algorithm ◽  
And Function

The neurotrophic tyrosine receptor kinase (NTRK) gene family encodes three tropomyosin receptor kinases (TRKA, TRKB, TRKC) that contribute to central and peripheral nervous system development and function. NTRK gene fusions are oncogenic drivers of various adult and paediatric tumours. Several methods have been used to detect NTRK gene fusions including immunohistochemistry, fluorescence in situ hybridisation, reverse transcriptase polymerase chain reaction, and DNA- or RNA-based next-generation sequencing. For patients with TRK fusion cancer, TRK inhibition is an important therapeutic target. Following the FDA approval of the selective TRK inhibitor, larotrectinib, as well as the ongoing development of multi-kinase inhibitors with activity in TRK fusion cancer, testing for NTRK gene fusions should become part of the standard diagnostic process. In this review we discuss the biology of NTRK gene fusions, and we present a testing algorithm to aid detection of these gene fusions in clinical practice and guide treatment decisions.

Staging of common paediatric tumours

2009 ◽  
Vol 39 (S3) ◽  
pp. 482-490 ◽  
Author(s):  
Hervé J. Brisse
Keyword(s):  
Paediatric Tumours

Histopathological Profile of Non-Haematological Paediatric Neoplasms in Hadoti Region of Rajasthan

2020 ◽  
Vol 7 (43) ◽  
pp. 2453-2457
Author(s):  
Praveen Kumar Bairwa ◽  
Neelu Vashist ◽  
Deepti Sukheeja
Keyword(s):  
Epidemiological Data ◽  
Developed Countries ◽  
Bone Tumours ◽  
Age Group ◽  
Malignant Tumours ◽  
Female Ratio ◽  
Paediatric Tumours ◽  
Haematological Neoplasms ◽  
Benign Tumours ◽  
Male To Female

BACKGROUND Malignancy is a major cause of childhood death in developed countries. In developing countries like India, paediatric tumours are rising day by day. Proper management of paediatric tumours needs epidemiological data in various geographical areas. The present study was carried out to classify and find out the histopathological profile of solid tumours of childhood and infancy in 0 - 14 years age group from 1st January 2015 to 31st December 2017. METHODS We studied histopathology reports of 173 paediatric tumours over a period of 3 years. All the biopsy cases of solid neoplasms in the age group 0 - 14 years were included. RESULTS In our study of 173 paediatric tumours, 133 (76.87 %) were benign and 40 (23.12 %) were malignant. Maximum incidence of malignant paediatric tumours was seen in the age group of 0 - 14 years [12.13 % (21 out of 173)], with male to female ratio of (1:1.3). Amongst the benign tumours, vascular tumours were most common [27.74 % (48 of 173 cases)], with highest incidence of haemangioma [68.75 % (33 of 48 cases)]. Amongst the malignant tumours, most common were bone tumours [6.35 % (11 of 173 cases)] and amongst bone tumours, Ewing’s sarcoma accounted for 63.63 % cases (7 of 11 cases). CONCLUSIONS The incidence of paediatric neoplasms in Hadoti region of Rajasthan is 0.75 % and the majority (54.33 %) of neoplasms occurred in 10 - 14 yrs. age group. KEYWORDS Histopathology, Paediatric, Non-Haematological Neoplasms

scholarly journals SP-0005: Role of brachytherapy in the management of paediatric tumours

2016 ◽  
Vol 119 ◽  
pp. S2 ◽  
Author(s):  
C. Haie-Meder ◽  
H. Martelli ◽  
C. Chargari ◽  
I. Dumas ◽  
V. Minard-Colin
Keyword(s):  
Paediatric Tumours
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