Histopathological Profile of Non-Haematological Paediatric Neoplasms in Hadoti Region of Rajasthan

2020 ◽  
Vol 7 (43) ◽  
pp. 2453-2457
Author(s):  
Praveen Kumar Bairwa ◽  
Neelu Vashist ◽  
Deepti Sukheeja

BACKGROUND Malignancy is a major cause of childhood death in developed countries. In developing countries like India, paediatric tumours are rising day by day. Proper management of paediatric tumours needs epidemiological data in various geographical areas. The present study was carried out to classify and find out the histopathological profile of solid tumours of childhood and infancy in 0 - 14 years age group from 1st January 2015 to 31st December 2017. METHODS We studied histopathology reports of 173 paediatric tumours over a period of 3 years. All the biopsy cases of solid neoplasms in the age group 0 - 14 years were included. RESULTS In our study of 173 paediatric tumours, 133 (76.87 %) were benign and 40 (23.12 %) were malignant. Maximum incidence of malignant paediatric tumours was seen in the age group of 0 - 14 years [12.13 % (21 out of 173)], with male to female ratio of (1:1.3). Amongst the benign tumours, vascular tumours were most common [27.74 % (48 of 173 cases)], with highest incidence of haemangioma [68.75 % (33 of 48 cases)]. Amongst the malignant tumours, most common were bone tumours [6.35 % (11 of 173 cases)] and amongst bone tumours, Ewing’s sarcoma accounted for 63.63 % cases (7 of 11 cases). CONCLUSIONS The incidence of paediatric neoplasms in Hadoti region of Rajasthan is 0.75 % and the majority (54.33 %) of neoplasms occurred in 10 - 14 yrs. age group. KEYWORDS Histopathology, Paediatric, Non-Haematological Neoplasms

2013 ◽  
Vol 40 (2) ◽  
pp. 175-178
Author(s):  
UA Shehu ◽  
SA Adegoke ◽  
U Abdulsalam ◽  
M Ibrahim ◽  
OA Oyelami ◽  
...  

Background: Cancer is a public health problem worldwide affecting all categories of persons. It is the second common cause of death in developed countries and among the three leading causes of death in developing countries.Objective: To compare the patterns of malignant childhood tumours intwo tertiary hospitals in the north- Western and South western Nigeria.Methods: Retrospective studies of childhood malignancies diagnosedat Aminu Kano Teaching Hospital (AKTH), Kano and Obafemi Awolowo University Teaching Hospital Complex (OAUTHC) (Ife Hospital Unit, Ile-Ife and Wesley Guild Hospital Unit, Ilesa, Osun state) were undertaken from January, 2001 to December, 2010. The patterns of childhood cancers inthese hospitals were compared.Results: Four hundred and ten children aged 7 months to 15 years were admitted at AKTH with malignancies of which 236 were males and 174 females with male to female ratio of 1.4:1. At OAUTHC, 568 children aged two months to 15 years were admitted with malignancies over the ten year period. There were 401 males and 167 females, with male to female ratio of 2.4:1. Lymphomas were the commonest type of malignancy in both centers, which accounted for 47.3% and 59.7% at AKTH and OAUTHCrespectively. Retinoblastoma was the second commonest tumour atAKTH constituting 14.9% of all malignancies followed by nephroblastomaand acute leukemias. In contrast, acute leukemias were the second commonest malignancy at OAUTHC accounting for 12.7% of all malignancies followed by retinoblastoma and nephroblastoma. Tumoursof central nervous system were observed to be commoner at AKTH, while bone tumours were commoner at OAUTHC.Conclusion: The pattern of childhood cancer varies rather little betweendifferent regions in Nigeria, with malignant lymphomas being the most common as is the case in most developing countries. However, the findings in this study suggest that there is variation in prevalence of leukemia, CNS and bone tumours in northern and southern Nigeria.Key words: Childhood, malignant tumours, pattern, teaching hospitals,Nigeria


Author(s):  
Ben Turney ◽  
John Reynard

In developed countries, the lifetime prevalence of kidney stones is around 10% and most commonly affects people in the working age-group. The incidence is increasing internationally. After passage of a first stone, the risk of recurrence is high. Direct and indirect costs involved in treating stones are considerable. Intrinsic risk factors include age, gender, genetics, and metabolic syndromes. The incidence of stone disease peaks between the ages of 20 and 60 years. While historically the male to female ratio was around 3:1, the gender gap is closing. The reasons for increased incidence are due in part to increased detection through better imaging but also due to environmental factors (e.g. diet, obesity, diabetes, dehydration) which put more people with an underlying genetic predisposition at risk. Despite the increasing prevalence of kidney stones, the majority are categorized as idiopathic.


2020 ◽  
Vol 8 (1) ◽  
pp. 93-99
Author(s):  
Balaji Varaprasad Mallula ◽  
Jithender Reddy Chintala ◽  
Srinadh Boppanna ◽  
S. Annapurna

Background: Stroke is the second single most common cause of death in the world causing approximately 6.7 million deaths each year. It has a greater disability impact on an individual than any other chronic disease. The aim of the study is to review the value of CTA in detection and evaluation of non-traumatic cervicocerebral vascular disease (stroke). Subjects & Methods: A prospective observational study conducted in the Department of Radiodiagnosis, Kamineni Hospitals, L.B. Nagar, Hyderabad over 60 patients during April 2016 to May 2017. Results: Out of 60 patients, 35(58.3%) patients had ischemic stroke, 25(41.6%) had hemorrhagic stroke. Overall stroke was seen mostly in the age group of 61-70 (28.3%) years, with a Male to female ratio of 3:2. Conclusion: Hypertension was the most common risk factor associated with this disease, followed by diabetes. CTA helps in accurate diagnosis, risk stratification and planning management protocols.


Author(s):  
CC Nwafor ◽  
K Obioha ◽  
TO Akhiwu

Ascites is a symptom that can originate due to diverse pathologies. A lot of investigations including ascitic fluid cytology (AFC) can be done on it to help determine its origin. The aim of this study, is to document the findings and highlight the importance of AFC in patient care in Uyo. All AFC reports and slides in the Department of Histopathology, University of Uyo were retrieved, reviewed and used for this study. The age ranged from 1.5 – 80 years with mean age, 41.79 (±17.23) years. About 71.8% of the ascitic fluid (AF) specimens were from patients between the 3rd and 6th decade. Females predominated in all age groups expect 10-19 year's group, with a male to female sex ratio of 1:2.4. Malignant cells were seen in 28.7% of all the samples, while 51.2% were negative for malignant cells. Malignant cells were seen in 4 (6.7%), 11 (18.3%) and 6 (10%) of the AFC performed due to various liver pathologies, ovarian malignancies and intra-abdominal malignancies respectively. Malignant cells were found more in females with a male to female ratio of 1: 3.6. Age group 40-49 years accounted for most of the malignant cases (26.6%). The pattern of AFC in Uyo is similar to the pattern in other parts of Nigeria


Author(s):  
Krystian Kazubski ◽  
Łukasz Tomczyk ◽  
Piotr Morasiewicz

The purpose of our study was to comprehensively assess the effect of the COVID-19 pandemic on knee and shoulder arthroscopy performed in an orthopedic department of a university hospital in Poland. This study compared the data on all shoulder and knee arthroscopy procedures performed in two different periods: The period of the COVID-19 pandemic in Poland (from March 4, 2020, to October 15, 2020) and the corresponding period prior to the pandemic (March 4, 2019, to October 15, 2019). The study evaluated epidemiological data, demographic data, and hospital stay duration. The total number of arthroscopy procedures conducted in the evaluated period in 2020 was approximately 8.6% higher than that in the corresponding 2019 period. The mean duration of hospital stay for orthopedic patients after their knee or shoulder arthroscopy was 3.1 days in 2020 and 2.8 days in 2019. Our study revealed the mean age of arthroscopy patients during the pandemic to be lower at 48.4 years than the 51.2 years recorded in 2019. The male-to-female ratio was shown to be lower at .85 during the pandemic, having decreased from 1.5 in 2019. The COVID-19 pandemic did not reduce the number of arthroscopy performed at our center, and the mean age of the patients did not change. However, the pandemic had a marked effect on the mean duration of hospital stay and male-to-female ratio.


2014 ◽  
Vol 2014 ◽  
pp. 1-5 ◽  
Author(s):  
Anita Omhare ◽  
Sanjeev Kumar Singh ◽  
Jitendra Singh Nigam ◽  
Ankit Sharma

Background. FNAC is a useful method for evaluating suspicious salivary glands lesions due to its low cost, minimum morbidity, rapid turnaround time, high specificity, and sensitivity. Aim. To know the frequency of the salivary gland lesions and cytohistological correlation in the Jhansi region, Uttar Pradesh, India. Material and Methods. In present study 124 cases were included and cytohistological correlation was made in 86 cases only. FNA was performed by using a 23/24-gauge needle without local anaesthesia. Air dried and 95% ethyl alcohol fixed wet smears were stained with Giemsa stain and Papanicolaou stain, respectively. Paraffin embedded tissue sections were stained with Haematoxylin and Eosin. Results. Parotid gland was the most commonly involved salivary gland. The commonest age group was 20 to 29 years, 30 to 39 years, and 60 to 69 years for nonneoplastic lesions, benign tumours, and malignant tumours, respectively. The overall male to female ratio was 1.17 : 1. The diagnostic accuracy of FNAC was 100%, 93.3%, and 88.2% for nonneoplastic lesions, benign tumours, and malignant tumours, respectively. Conclusion. The high accuracy, sensitivity, and specificity of FNAC confirm that preoperative cytology is a useful, quick, reliable diagnostic technique for rapid diagnosis and suitable for developing countries.


2018 ◽  
Vol 17 (06) ◽  
pp. 206-209
Author(s):  
Roshan Koul ◽  
Amna Al-Fuitaisi ◽  
Nabil Macki ◽  
Prakash Kurubarahalli Patel ◽  
Haleema Al-Balushi ◽  
...  

Objective Guillain–Barre's syndrome (GBS) is an acute immune-mediated polyradiculoneuropathy seen in all ages but mostly in the adult population. We aim to report the incidence of GBS in children under 15 years of age in Oman, a Gulf country. Materials and Methods All children with GBS under 15 years of age were included in the study from January 2002 to December 2016. The data were compiled in Microsoft Excel format and analysis was performed using SPSS, version 17.0. Population-based age- and sex-specific rates of GBS were calculated using the estimated population for each 5-year period based on 2004, 2009, and 2014 mid-year population, respectively. Relative risk and 95% confidence intervals of GBS at different age categories were calculated using the overall incidence of GBS in those under 15 years as reference. Results The average annual incidence in those under 15 years was 3.1/100,000. Age-specific incidence was 4.0/100,000 in the age group 0 to 9 years and 4.7/100,000 in age group 0 to 4 years. Sixty percent had evidence of preceding infections, and the male to female ratio was 1.8:1. Fifty percent had cranial nerve involvement and 18% needed mechanical ventilation. Five percent had residual weakness. Intravenous immunoglobulins (IVIGs) were used in all, and 3.3% required plasmapheresis when they did not improve with IVIG. Clinical profile of the GBS was not different from the rest reported in the literature. Conclusion The incidence of GBS in Oman was 3.1/100,000 (range: 2.7–3.5 cases/100,000) in children under 15 years of age. The GBS is a smaller proportion among the total acute flaccid paralysis cases.


2019 ◽  
Vol 28 (1-2) ◽  
pp. 1-13
Author(s):  
Taheng Sebayang ◽  
Atan Baas Sinuhaji ◽  
Tyahaya Bangun ◽  
Manihar D. Marbun ◽  
A. H. Sutanto

The number of children attending the Pediatric Outpatient Clinic of Pirngadi Hospital, Medan, during 1982 was 15.375. Out of these, 1246 (8.1%) had gastroenteritis. Most of the patients (1046 or 83.94%) were under two years old. The male to female ratio was 1.6: I. The peak incidence for allendance was in January, April, and May. Of 1057 patients under  five years old, 383 (36.2%) also had malnutrition. The highest percentage (70. 75%) of those who had malnutrition was found in the I to 2 years age group. Of 370 patients whose Hb level was examined, 185 (50%) had anemia. The highest percentage (67.02%) was in the below 1 year group. Only 360 (28.8%) of gastroenteritis cases received oral rehydration solution. There were 23 (1.85%) cases in which diarrhea lasted longer than 7 days. The number of patients admitted to the ward was 213 (17.07%), and the highest percentage was in the above 3 years age group. The largest number of hospitalized patients was in January (43), February (21), and April (28); while the highest percentage was in April (20.40%), June (21.42%) and August (31.42%). Peak rainfall in Medan during 1982 was in October, November, and December, i.e. much 322.2 mmm,  366.4 and 382 mm, respectively.


2021 ◽  
Author(s):  
Wenli He ◽  
Danhong Xu ◽  
Jiafeng Wang ◽  
Yuze Shen ◽  
Zheng Lin ◽  
...  

Abstract BackgroundLittle is known about the gender characteristics and the Corona Virus Disease 2019(COVID-19) impact on psychiatric department outpatients in general hospitals in China. MethodsWe retrospectively collected 225,947 outpatient clinic records before and during COVID-19 pandemic from January 1, 2019 to December 31, 2020 in the psychiatric clinic of 3 general hospitals, gender composition of patients was analyzed in different five age groups and nine diagnostic categories at three levels: total patient visits, number of patients and number of first-visit patients. ResultsThe total male-to-female ratio of psychiatric outpatient records in 3 general hospitals from 2019 to 2020 was 1:1.69. Women were more common in all age groups and the male-to-female ratio of 2020 was expanded compared to that of 2019, especially in age group below 34 years old and anxiety disorders category. Most mental disorders showed higher demands for females than that for males except Mental and behavioral disorders due to psychoactive substance use with the male-to-female ratio was 1:0.05. Compared to 2019, the proportions of women were expanded especially in age group below 34 years old, and anxiety disorder and undetermined diagnosis categories were significantly increased in 2020. ConclusionsThe demand for female psychiatric outpatient services is obviously higher than that for males. It is necessary to pay more attention to explore targeted mechanism or psychosocial service strategy for female patients with mental disorders. Trial registration: ChiCTR2100044894, March 31,2021 retrospectively registered.


2020 ◽  
Vol 7 (3) ◽  
pp. 818
Author(s):  
Dwaipayan Samaddar ◽  
Jaya B. Samaddar ◽  
Ahmad M. Aziz

Background: Salivary gland tumors (SGT) are uncommon tumors of diverse histopathology accounting for <2% of all neoplasms. Early diagnosis differentiates between benign and malignant SGT and less extensive surgical procedure can be performed. The objective is to study the spectrum of primary SGT with special emphasis on their distribution, treatment and outcome at a rural tertiary care centre.Methods: A prospective observational study was conducted on 30 consecutive primary SGT patients attending the Departments of Surgery and Otorhinolaryngology of North Bengal Medical College and Hospital over a period of one and half years. All patients were clinically evaluated, investigated, treated accordingly and followed up during the period of study. Data was collected and compiled in Excel sheet and analysed using GraphPad Software and GraphPad QuickCalcs 2018 (San Diego, CA). A p value <0.05 was considered statistically significant.Results: Maximum patients (83.3%) were in the age range of 31-60 years. The male to female ratio was 1:4 for benign tumours and 1:1 for malignant tumours. Malignant cases were 66.67%. Involvement of parotid gland was the commonest (43.3%) and mostly presented with swelling (73.3%). Pleomorphic salivary adenoma was the commonest benign tumor (33.3%) and mucoepidermoid carcinoma was the commonest malignant tumor (16.7%). Permanent facial palsy was observed in 2 (9.5%) and recurrence in 4 patients (19%).Conclusions: SGT are rare and present in various modes. Malignant cases were singularly more in this study.


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