Apparent Treatment-Resistant Hypertension and Chronic Kidney Disease: Another Cardiovascular–Renal Syndrome?

2017 ◽  
pp. 25-38 ◽  
Author(s):  
Ferruh Artunc
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Resistant Hypertension ◽  
Treatment Resistant

scholarly journals FP092CLINICAL CHARACTERISTICS OF APPARENT TREATMENT-RESISTANT HYPERTENSION IN CHRONIC KIDNEY DISEASE PATIENTS EVALUATED BY 24 HOUR AMBULATORY BLOOD PRESSURE MONITORING

2015 ◽  
Vol 30 (suppl_3) ◽  
pp. iii97-iii97
Author(s):  
Biljana Gerasimovska Kitanovska ◽  
Stevka Bogdanovska ◽  
Svetlana Pavleska Kuzmanovska ◽  
Vesna Gerasimovska ◽  
Aleksandar Sikole
Keyword(s):  
Blood Pressure ◽  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Ambulatory Blood Pressure Monitoring ◽  
Ambulatory Blood Pressure ◽  
Resistant Hypertension ◽  
Blood Pressure Monitoring ◽  
Treatment Resistant ◽  
Pressure Monitoring

scholarly journals Effect of Arteriovenous Fistula Creation on Systolic and Diastolic Blood Pressure in Patients With Pre-dialysis Advanced Chronic Kidney Disease

2019 ◽  
Vol 32 (9) ◽  
pp. 858-867 ◽  
Author(s):  
Roy O Mathew ◽  
Jerome Fleg ◽  
Janani Rangaswami ◽  
Bo Cai ◽  
Arif Asif ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Arteriovenous Fistula ◽  
Resistant Hypertension ◽  
Repeated Measures ◽  
Treatment Resistant ◽  
Advanced Chronic Kidney Disease ◽  
Stage Renal Disease ◽  
End Stage

AbstractBACKGROUNDCentral arteriovenous fistula (cAVF) has been investigated as a therapeutic measure for treatment-resistant hypertension in patients without advanced chronic kidney disease (CKD). There is considerable experience with the use of AVF for hemodialysis in patients with end-stage renal disease (ESRD). However, there is sparse data on the blood pressure (BP) effects of an AVF among patients with ESRD. We hypothesized that AVF creation would significantly reduce BP compared with patients who did not have an AVF among patients with ESRD before starting hemodialysis.METHODSBPs were compared during the 12 months before hemodialysis initiation in 399 patients with an AVF or AV graft created and 4,696 patients without either.RESULTSAfter propensity score matching 1:2 ratio (AVF to no AVF), repeated measures analysis of variance revealed significant reductions of –1.7 mm Hg systolic and –3.9 mm Hg diastolic BP 12 months in patients after AVF creation; P = 0.025 and P < 0.001, respectively, compared with those with no AVF.CONCLUSIONSThese findings suggest that AVF creation results in modest BP reduction in patients with pre-dialysis ESRD who require AVF for eventual hemodialysis therapy. Preferential diastolic BP reduction suggests that greater work is needed to characterize the ideal patient subset in which to use cAVF for treatment-resistant hypertension in those without advanced CKD.

scholarly journals Inflammation and Apparent Treatment-Resistant Hypertension in Patients With Chronic Kidney Disease

Hypertension ◽  
2019 ◽  
Vol 73 (4) ◽  
pp. 785-793 ◽  
Author(s):  
Jing Chen ◽  
Joshua D. Bundy ◽  
L. Lee Hamm ◽  
Chi-yuan Hsu ◽  
James Lash ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Resistant Hypertension ◽  
Treatment Resistant

Global prevalence of resistant hypertension: a meta-analysis of data from 3.2 million patients

Heart ◽  
2018 ◽  
Vol 105 (2) ◽  
pp. 98-105 ◽  
Author(s):  
Jean Jacques Noubiap ◽  
Jobert Richie Nansseu ◽  
Ulrich Flore Nyaga ◽  
Paule Sandra Sime ◽  
Innocent Francis ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Resistant Hypertension ◽  
Antihypertensive Drugs ◽  
Meta Analysis ◽  
White Coat Hypertension ◽  
Reference List ◽  
Treatment Resistant ◽  
New Treatments ◽  
Q Statistic

ObjectiveWe conducted the first systematic review and meta-analysis to estimate the specific prevalence of apparent treatment-resistant, pseudo-resistant and true-resistant hypertension among treated patients with hypertension globally.MethodsWe conducted a search in PubMed, EMBASE, Web of Science and Global Index Medicus to identify articles published from inception to 30 September 2017, and searched the reference list of retrieved articles. We used a random-effects model to estimate the prevalence of resistant hypertension across studies and heterogeneity was assessed via the χ² test on Cochran’s Q statistic.ResultsWe included 91 studies published between 1991 and 2017 reporting data of a pooled sample of 3 207 911 patients with hypertension on antihypertensive drugs globally. Most of the studies (n=64, 70%) only used office blood pressure (BP) measurement. In the general, population of treated patients with hypertension, the prevalence of true-resistant, apparent treatment-resistant and pseudo-resistant hypertension were 10.3% (95% CI 7.6% to 13.2%), 14.7% (95% CI 13.1% to 16.3%) and 10.3% (95% CI 6.0% to 15.5%). The prevalence of true-resistant hypertension was 22.9% (95% CI 19.1% to 27.0%), 56.0% (95% CI 52.7% to 59.3%) and 12.3% (95% CI 1.7% to 30.5%) in chronic kidney disease, renal transplant and elderly patients, respectively.ConclusionsThis study shows a high prevalence of true-resistant hypertension. This prevalence is lower than that of apparent treatment-resistant hypertension, demonstrating the importance to exclude causes of pseudo-resistant hypertension including white-coat hypertension with the use of ambulatory BP measurement. The burden of resistant hypertension is highest in patients with chronic kidney disease. New treatments for resistant hypertension are highly needed, considering the disastrous complications of the disease.

scholarly journals Apparent Treatment Resistant Hypertension, Blood Pressure Control and the Progression of Chronic Kidney Disease in Patients with Type 2 Diabetes

2018 ◽  
Vol 43 (2) ◽  
pp. 422-438 ◽  
Author(s):  
Francesca Viazzi ◽  
Eulalia Greco ◽  
Antonio Ceriello ◽  
Paola Fioretto ◽  
Carlo Giorda ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Type 2 Diabetes ◽  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Blood Pressure Control ◽  
Resistant Hypertension ◽  
Pressure Control ◽  
Treatment Resistant

scholarly journals Chronic kidney disease and incident apparent treatment-resistant hypertension among blacks: Data from the Jackson Heart Study

2017 ◽  
Vol 19 (11) ◽  
pp. 1117-1124 ◽  
Author(s):  
Rikki M. Tanner ◽  
Daichi Shimbo ◽  
Marguerite R. Irvin ◽  
Tanya M. Spruill ◽  
Samantha G. Bromfield ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Resistant Hypertension ◽  
Jackson Heart Study ◽  
Treatment Resistant ◽  
Heart Study

SP049INFLAMMATION AND APPARENT TREATMENT RESISTANT HYPERTENSION IN PATIENTS WITH CHRONIC KIDNEY DISEASE

2019 ◽  
Vol 34 (Supplement_1) ◽  
Author(s):  
Jing Chen ◽  
D Bundy Joshua ◽  
Lee Hamm L ◽  
Chi-Yuan Hsu ◽  
James Lash ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Resistant Hypertension ◽  
Treatment Resistant

scholarly journals Apparent Treatment-Resistant Hypertension and Chronic Kidney Disease: Another Cardiovascular-Renal Syndrome?

2014 ◽  
Vol 21 (6) ◽  
pp. 489-499 ◽  
Author(s):  
Sreekanth Vemulapalli ◽  
Crystal C. Tyson ◽  
Laura P. Svetkey
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Resistant Hypertension ◽  
Treatment Resistant
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