Detecting Attractors in Biological Models with Uncertain Parameters

2017 ◽  
pp. 40-56 ◽  
Author(s):  
Jiří Barnat ◽  
Nikola Beneš ◽  
Luboš Brim ◽  
Martin Demko ◽  
Matej Hajnal ◽  
...  
Keyword(s):  
Uncertain Parameters ◽  
Biological Models

Trajectory Tracking Control Applied to an Electro-Hydraulic Actuator With Uncertain Parameters.

2019 ◽  
Author(s):  
Josiel Gouvêa ◽  
Carlos Alberto Correia ◽  
Alessandro Zachi ◽  
Wallace Moreira Bessa
Keyword(s):  
Trajectory Tracking ◽  
Tracking Control ◽  
Uncertain Parameters ◽  
Hydraulic Actuator ◽  
Trajectory Tracking Control

NON-STANDARD DISCRETIZATION METHODS FOR SOME BIOLOGICAL MODELS

2009 ◽  
Vol 12 (1) ◽  
pp. 126-133
Author(s):  
Shawki A. M. Abbas ◽  
Keyword(s):  
Biological Models ◽  
Discretization Methods

scholarly journals Integrating Biosensors in Organs-on-Chip Devices: A Perspective on Current Strategies to Monitor Microphysiological Systems

Biosensors ◽  
2020 ◽  
Vol 10 (9) ◽  
pp. 110 ◽  
Author(s):  
Erika Ferrari ◽  
Cecilia Palma ◽  
Simone Vesentini ◽  
Paola Occhetta ◽  
Marco Rasponi
Keyword(s):  
Imaging Techniques ◽  
Biological Models ◽  
Electromechanical Properties ◽  
Human Organs ◽  
Tissue Constructs ◽  
Microphysiological Systems ◽  
Metabolic Activities ◽  
On Chip ◽  
Chip Analysis

Organs-on-chip (OoC), often referred to as microphysiological systems (MPS), are advanced in vitro tools able to replicate essential functions of human organs. Owing to their unprecedented ability to recapitulate key features of the native cellular environments, they represent promising tools for tissue engineering and drug screening applications. The achievement of proper functionalities within OoC is crucial; to this purpose, several parameters (e.g., chemical, physical) need to be assessed. Currently, most approaches rely on off-chip analysis and imaging techniques. However, the urgent demand for continuous, noninvasive, and real-time monitoring of tissue constructs requires the direct integration of biosensors. In this review, we focus on recent strategies to miniaturize and embed biosensing systems into organs-on-chip platforms. Biosensors for monitoring biological models with metabolic activities, models with tissue barrier functions, as well as models with electromechanical properties will be described and critically evaluated. In addition, multisensor integration within multiorgan platforms will be further reviewed and discussed.

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