Conditional Mutagenesis Reveals Immunological Functions of Widely Expressed Genes: Activation Thresholds, Homeostatic Mechanisms and Disease Models

Conditional Mutagenesis: An Approach to Disease Models - Handbook of Experimental Pharmacology ◽

10.1007/978-3-540-35109-2_12 ◽

2007 ◽

pp. 289-314 ◽

Author(s):

J. Roes

Keyword(s):

Disease Models ◽

Conditional Mutagenesis ◽

Homeostatic Mechanisms

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Conditional Mutagenesis: An Approach to Disease Models

10.1007/978-3-540-35109-2 ◽

2007 ◽

Keyword(s):

Disease Models ◽

Conditional Mutagenesis

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Changes in metabotropic glutamate receptor expression in the basal ganglia of Parkinson's disease models

Neuroscience Research ◽

10.1016/s0168-0102(00)81571-0 ◽

2000 ◽

Vol 38 ◽

pp. S121

Author(s):

M Takada

Keyword(s):

Parkinson’S Disease ◽

Parkinson's Disease ◽

Basal Ganglia ◽

Glutamate Receptor ◽

Metabotropic Glutamate Receptor ◽

Receptor Expression ◽

Disease Models ◽

Metabotropic Glutamate

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Establishment of Human Cellular Disease Models for Wilson Disease

Case Medical Research ◽

10.31525/ct1-nct03867526 ◽

2019 ◽

Author(s):

Keyword(s):

Wilson Disease ◽

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Faculty Opinions recommendation of Endocannabinoid-mediated rescue of striatal LTD and motor deficits in Parkinson's disease models.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1067031.519982 ◽

2007 ◽

Author(s):

Michele A Basso

Keyword(s):

Parkinson’S Disease ◽

Parkinson's Disease ◽

Motor Deficits ◽

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Faculty Opinions recommendation of Expression profiling of Huntington's disease models suggests that brain-derived neurotrophic factor depletion plays a major role in striatal degeneration.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1092788.547713 ◽

2007 ◽

Author(s):

Allan Tobin

Keyword(s):

Huntington's Disease ◽

Huntington’S Disease ◽

Neurotrophic Factor ◽

Expression Profiling ◽

Brain Derived Neurotrophic Factor ◽

Disease Models ◽

Striatal Degeneration

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Faculty Opinions recommendation of Reversal of long-term dendritic spine alterations in Alzheimer disease models.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1168191.630333 ◽

2009 ◽

Author(s):

Frank LaFerla

Keyword(s):

Alzheimer Disease ◽

Dendritic Spine ◽

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Faculty Opinions recommendation of Systematic discovery of nonobvious human disease models through orthologous phenotypes.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.2687956.2820055 ◽

2010 ◽

Author(s):

Ian Dunham

Keyword(s):

Human Disease ◽

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Faculty Opinions recommendation of Sodium selenate mitigates tau pathology, neurodegeneration, and functional deficits in Alzheimer's disease models.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.5008960.4940058 ◽

2010 ◽

Author(s):

George Perry

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Disease Models ◽

Sodium Selenate ◽

Tau Pathology ◽

Functional Deficits

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Faculty Opinions recommendation of Direct production of mouse disease models by embryo microinjection of TALENs and oligodeoxynucleotides.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.717989823.793475567 ◽

2013 ◽

Author(s):

Lily Jan ◽

Shaohua Xiao

Keyword(s):

Disease Models ◽

Direct Production

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Faculty Opinions recommendation of Connectivity mapping uncovers small molecules that modulate neurodegeneration in Huntington's disease models.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.725835213.793510305 ◽

2015 ◽

Author(s):

John Lowe

Keyword(s):

Huntington's Disease ◽

Small Molecules ◽

Huntington’S Disease ◽

Disease Models ◽

Connectivity Mapping

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