Autonomous Adenoma

2011 ◽  
pp. 181-185
Author(s):  
Ernst Nyström ◽  
Gertrud E. B. Berg ◽  
Svante K. G. Jansson ◽  
Ove Tørring ◽  
Stig V. Valdemarsson
Keyword(s):  
Autonomous Adenoma

Ultrasonic Evaluation of "Silent Regions" in the Thyroid Scintiscan

1978 ◽  
Vol 17 (01) ◽  
pp. 16-23 ◽  
Author(s):  
Ch. L. Zollikofer ◽  
J. Wewerka ◽  
Th. Frank
Keyword(s):  
Needle Biopsy ◽  
Clinical Course ◽  
Stimulation Test ◽  
Evaluation Procedure ◽  
Sonographic Diagnosis ◽  
Non Invasive ◽  
Evaluation Procedures ◽  
Ultrasonic Evaluation ◽  
Invasive Evaluation ◽  
Autonomous Adenoma

35 patients with scintigraphically silent thyroid regions without palpable cold nodules were further evaluated by ultrasonography. In 33 cases the sonographic diagnosis was confirmed by other examinations or the clinical course. 2 cases were misinterpreted right at the beginning of our series.The use of ultrasonography in evaluating silent thyroid regions in the totally decompensated autonomous adenoma, in unilateral thyroid aplasia, thyroiditis and hyperthyroidism is shown to be a reliable and valuable supplement to the clinical and radioisotopic evaluation procedures. When differentiating the totally decompensated autonomous adenoma from unilateral thyroid aplasia a stimulation test need not be performed in most cases. Suspected thyroiditis can be confirmed in a simple way. Being a non-invasive evaluation procedure, ultrasonography should be used before performing a needle biopsy.

scholarly journals TRF-STIMULATION-TEST IN HYPOTHALAMIC AND PITUITARY DISEASES, AND IN AUTONOMOUS ADENOMA OF THE THYROID

1972 ◽  
Vol 68 (3_Suppl) ◽  
pp. S1
Author(s):  
C. R. Pickardt ◽  
F. Erhardt ◽  
W. Geiger ◽  
R. Fahlbusch ◽  
H. G. Heinze ◽  
...  
Keyword(s):  
Stimulation Test ◽  
Pituitary Diseases ◽  
Autonomous Adenoma

Autonomous adenoma of the thyroid in infancy

1975 ◽  
Vol 120 (1) ◽  
pp. 51-57 ◽  
Author(s):  
Siegfried Zabransky ◽  
Klaus Koppenhagen ◽  
J�rgen Waldschmidt
Keyword(s):  
Autonomous Adenoma

scholarly journals Mortality from thyroid cancer in patients with hyperthyroidism: the Theagenion Cancer Hospital experience

2008 ◽  
Vol 159 (6) ◽  
pp. 799-803 ◽  
Author(s):  
Kalliopi Pazaitou-Panayiotou ◽  
Petros Perros ◽  
Maria Boudina ◽  
George Siardos ◽  
Apostolos Drimonitis ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Previous History ◽  
Distant Metastases ◽  
Northern Greece ◽  
Hot Nodule ◽  
Increased Risk ◽  
History Of ◽  
The Relationship ◽  
Diagnosis Of Thyroid Cancer ◽  
Autonomous Adenoma

BackgroundThyroid carcinoma has been reported in patients operated for different types of hyperthyroidism and the probability of a hot nodule being malignant seems to be low. The aim of the present study was to explore the relationship between thyroid cancer, hyperthyroidism and outcome in a large cohort of patients who presented to a tertiary cancer centre in Northern Greece.PatientsAmong 720 patients treated for thyroid cancer, 60 had a concomitant diagnosis of hyperthyroidism due to Graves' disease (n=14), solitary autonomous adenoma (n=17), or multinodular goiter (n=29). Adverse prognostic factors were common in patients with a previous history of hyperthyroidism at the time of diagnosis of thyroid cancer, including cases where the cancer was discovered coincidentally after thyroid surgery for hyperthyroidism and cases where tumor size was more than 10 mm.ResultsIn 10 out of 17 patients with hyperthyroidism due to solitary autonomous adenomas, the tumor was located within the hot nodule and two of these patients developed local and distant metastases and died from the disease 4 and 15 years after thyroidectomy.ConclusionClinicians managing patients with hyperthyroidism need to be aware of the possible increased risk of thyroid cancer in this patient group.

Hyperthyroidism and thyroid carcinoma

1991 ◽  
Vol 124 (2) ◽  
pp. 146-151 ◽  
Author(s):  
S. Ahuja ◽  
H. Ernst
Keyword(s):  
Thyroid Carcinoma ◽  
Thyroid Nodules ◽  
Differentiated Thyroid Carcinoma ◽  
The Other ◽  
Multinodular Goitre ◽  
Papillary Tumour ◽  
History Of ◽  
Node Metastases ◽  
Occult Thyroid Carcinoma ◽  
Autonomous Adenoma

Abstract. Twenty-two of 251 patients with differentiated thyroid carcinoma suffered from or had a history of hyperthyroidism. They were hyperthyroid with a diffuse goitre (N=4), a diffuse goitre with a cold nodule (N= 10), a multinodular goitre (N=6), and an autonomous adenoma (N=2). Among the 22 patients, more than one fourth had an occult thyroid carcinoma with a diameter of 1 cm or less, those with the papillary tumour types, less frequently had lymph node metastases than the total group of patients with papillary carcinomas (13.3 vs 35.6%). The clinical courses of the 22 patients resembled those of the other thyroid carcinoma patients whose age and initial findings were comparable. In 643 patients who underwent surgery for hyperthyroidism the incidence of thyroid carcinoma was 2.3%. The increase in coincidence of hyperthyroidism and thyroid carcinoma repeatedly reported in recent years is probably ascribable primarily to extensive and improved diagnostics and not to a direct connection between hyperthyroidism and development of thyroid carcinoma. On the other hand, our findings do confirm that, even in the presence of hyperthyroidism, all thyroid nodules require careful diagnostics for exclusion of malignancy.

Long-term follow-up in patients with autonomous thyroid adenoma

1993 ◽  
Vol 128 (1) ◽  
pp. 51-55 ◽  
Author(s):  
D Sandrock ◽  
T Olbricht ◽  
D Emrich ◽  
G Benker ◽  
D Reinwein
Keyword(s):  
Prognostic Value ◽  
Definitive Treatment ◽  
Thyroid Adenoma ◽  
Trh Test ◽  
Long Term Follow Up ◽  
Autonomous Adenoma ◽  
Observation Period ◽  
Treatment Surgery

A group of 375 untreated euthyroid patients with solitary autonomous adenoma of the thyroid were studied in a long-term follow-up (observation period 52.8 (mean)/46 (median), range 3–204 months). During the period of observation, 133 (34.2%) of all initially untreated patients underwent treatment (surgery, radioiodine, antithyroid medication) because of hyperthyroidism, mechanical problems, or at the patient's request. Sixty-seven patients developed hyperthyroidism resulting in a mean incidence of 4.1% per year. The incidence of hyperthyroidism increased during follow-up (3% in the first seven years, 10% in the following years). Age, sex, nodule size, initial scintigraphic appearance and the TRH test were of no individual prognostic value in predicting hyperthyroidism. Eleven of 14 patients with untreated hyperthyroidism became euthyroid without treatment during the time of follow-up. After iodine excess (by history or elevated iodine levels in urine, N=45), 14 patients (31%) developed hyperthyroidism. In conclusion, we recommend a definitive treatment of autonomous adenoma at least in patients with advanced age, concomitant diseases and a higher probability of iodine exposure.

Use of the thyroid 99Tcm scintiscan with lead-shield on the hot nodule in the diagnosis of autonomous adenoma

1987 ◽  
Vol 8 (4) ◽  
pp. 217-220 ◽  
Author(s):  
G. RIZZI ◽  
G. ARGIRÓ ◽  
L. GENTILE ◽  
G. CASTELLANO ◽  
C. BROSSA ◽  
...  
Keyword(s):  
Hot Nodule ◽  
Lead Shield ◽  
Autonomous Adenoma

Cushing's disease coexisting with a single macronodule simulating adenoma of the adrenal cortex

1986 ◽  
Vol 112 (3) ◽  
pp. 323-328 ◽  
Author(s):  
Sara Leiba ◽  
Bella Shindel ◽  
Itzhak Weinberger ◽  
Jacobs Fuchs ◽  
Zvi Rotenberg ◽  
...  
Keyword(s):  
Adrenal Cortex ◽  
Cushing’S Disease ◽  
Adrenal Adenoma ◽  
Cushing's Disease ◽  
Dynamic Tests ◽  
Nodular Hyperplasia ◽  
Pituitary Irradiation ◽  
Autonomous Adenoma ◽  
Stimulation Of

Abstract. A rare case of Cushing's disease coexisting with a single macronodule simulating adenoma of the adrenal cortex is presented. The basal and dynamic tests supported the diagnosis of Cushing's disease, whereas the CT-scan, ultrasound and iodocholesterol uptake were suggestive of a left adrenal adenoma. Treatment consisted of extirpation of the nodular gland followed by pituitary irradiation. The examination revealed a single macronodule with no histological membrane, surrounded by hyperplastic adrenocortex. Together with the three similar ones reported in the literature this case suggests that nodular hyperplasia may be an intermediary stage between diffuse hyperplasia and the appearance of an autonomous adenoma after long-term stimulation of the hyperplastic gland.

Untersuchungen zur effektiven Halbwertszeit des 131J bei der Radiojodbehandlung der Schilddrüsenautonomie

1991 ◽  
Vol 30 (03) ◽  
pp. 71-76
Author(s):  
R. Bares ◽  
U. Büll ◽  
B. Müller
Keyword(s):  
Time Course ◽  
Whole Body ◽  
Antithyroid Drugs ◽  
Graves Disease ◽  
Exact Determination ◽  
The Mean ◽  
Therapeutic Doses ◽  
Autonomous Adenoma ◽  
Benign Thyroid

In order to compute effective half-life of131I after application of therapeutic doses (Teff), the time course of whole-body radioactivity was evaluated retrospectively in 115 patients with benign thyroid diseases (multinodular autonomous adenoma, solitary autonomous adenoma or Graves’ disease). Because of a large overlap of Teff in the various diseases analyzed, courses of all patients who did (group Ts, 24 cases) or did not (group kTs, 91 cases) receive antithyroid drugs during therapy were summarized. In group Ts a mean Teff of 5.0 ± 0.9 d was found which was significantly (p <0.01) lower than the mean Teff of 6.3 ± 0.9 d in group kTs. We believe that the mean Teff is a practical alternative in radioiodine dosimetry if an exact determination of Teff cannot be performed because of shortage of time.

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