Neurogenesis in adult brain: understanding its mechanism and regulation

2004 ◽  
pp. 1-23 ◽  
Author(s):  
Xinyu Zhao ◽  
David Schaffer ◽  
F. H. Gage
Keyword(s):  
Adult Brain

Predicting Affective Cognitions in the Resting Adult Brain

2018 ◽  
Author(s):  
Keith Bush ◽  
Anthony Privratsky ◽  
Clinton Kilts
Keyword(s):  
Adult Brain

Role of melatonin in regulating neurogenesis: Implications for the neurodegenerative pathology and analogous therapeutics for Alzheimer’s disease

2020 ◽  
Vol 3 (2) ◽  
pp. 216-242 ◽  
Author(s):  
Mayuri Shukla ◽  
Areechun Sotthibundhu ◽  
Piyarat Govitrapong
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Adult Neurogenesis ◽  
Adult Brain ◽  
Therapeutic Approaches ◽  
Therapeutic Implications ◽  
Cell Proliferation And Differentiation ◽  
Proliferation And Differentiation ◽  
Progenitor Cell Proliferation

The revelation of adult brain exhibiting neurogenesis has established that the brain possesses great plasticity and that neurons could be spawned in the neurogenic zones where hippocampal adult neurogenesis attributes to learning and memory processes. With strong implications in brain functional homeostasis, aging and cognition, various aspects of adult neurogenesis reveal exuberant mechanistic associations thereby further aiding in facilitating the therapeutic approaches regarding the development of neurodegenerative processes in Alzheimer’s Disease (AD). Impaired neurogenesis has been significantly evident in AD with compromised hippocampal function and cognitive deficits. Melatonin the pineal indolamine augments neurogenesis and has been linked to AD development as its levels are compromised with disease progression. Here, in this review, we discuss and appraise the mechanisms via which melatonin regulates neurogenesis in pathophysiological conditions which would unravel the molecular basis in such conditions and its role in endogenous brain repair. Also, its components as key regulators of neural stem and progenitor cell proliferation and differentiation in the embryonic and adult brain would aid in accentuating the therapeutic implications of this indoleamine in line of prevention and treatment of AD.   

1H MR Spectroscopic Patterns of Normal Adult Brain

1996 ◽  
Vol 35 (4) ◽  
pp. 435 ◽  
Author(s):  
In Chan Song ◽  
Kee Hyun Chang ◽  
Kwan Hong Min ◽  
Dong Sung Kim ◽  
Moon Hee Han ◽  
...  
Keyword(s):  
Adult Brain ◽  
Normal Adult
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