Transmural Electrophysiologic and Scar Imaging on Porcine Heart with Chronic Infarction

2012 ◽  
pp. 23-32 ◽  
Author(s):  
Linwei Wang ◽  
Fady Dawoud ◽  
Ken C. L. Wong ◽  
Heye Zhang ◽  
Huafeng Liu ◽  
...  
Keyword(s):  
Porcine Heart

Dose Response Curves for Microwave Ablation in the Cardioplegia-Arrested Porcine Heart

2005 ◽  
Vol 8 (4) ◽  
pp. E269-E274 ◽  
Author(s):  
Sydney L. Gaynor ◽  
Gregory D. Byrd ◽  
Michael D. Diodato ◽  
Yosuke Ishii ◽  
Anson M. Lee ◽  
...  
Keyword(s):  
Dose Response ◽  
Microwave Ablation ◽  
Response Curves ◽  
Porcine Heart ◽  
Dose Response Curves

scholarly journals The relation of acyl transfer to the overall reaction of thiolase I from porcine heart.

1981 ◽  
Vol 256 (14) ◽  
pp. 7371-7377
Author(s):  
H.F. Gilbert ◽  
B.J. Lennox ◽  
C.D. Mossman ◽  
W.C. Carle
Keyword(s):  
Acyl Transfer ◽  
Porcine Heart

scholarly journals Comprehensive Analysis of Cardiac Xeno-Graft Unveils Rejection Mechanisms

2021 ◽  
Vol 22 (2) ◽  
pp. 751
Author(s):  
Min Young Park ◽  
Bala Murali Krishna Vasamsetti ◽  
Wan Seop Kim ◽  
Hee Jung Kang ◽  
Do-Young Kim ◽  
...  
Keyword(s):  
Graft Rejection ◽  
Molecular Mechanisms ◽  
Cardiac Fibrosis ◽  
Cardiac Tissue ◽  
Inflammatory Responses ◽  
Blood Parameters ◽  
Quantitative Real Time Pcr ◽  
Porcine Heart ◽  
End Stage Heart Failure ◽  
End Stage

Porcine heart xenotransplantation is a potential treatment for patients with end-stage heart failure. To understand molecular mechanisms of graft rejection after heart transplantation, we transplanted a 31-day-old alpha-1,3-galactosyltransferase knockout (GTKO) porcine heart to a five-year-old cynomolgus monkey. Histological and transcriptome analyses were conducted on xenografted cardiac tissue at rejection (nine days after transplantation). The recipient monkey’s blood parameters were analyzed on days −7, −3, 1, 4, and 7. Validation was conducted by quantitative real-time PCR (qPCR) with selected genes. A non-transplanted GTKO porcine heart from an age-matched litter was used as a control. The recipient monkey showed systemic inflammatory responses, and the rejected cardiac graft indicated myocardial infarction and cardiac fibrosis. The transplanted heart exhibited a total of 3748 differentially expressed genes compared to the non-transplanted heart transcriptome, with 2443 upregulated and 1305 downregulated genes. Key biological pathways involved at the terminal stage of graft rejection were cardiomyopathies, extracellular interactions, and ion channel activities. The results of qPCR evaluation were in agreement with the transcriptome data. Transcriptome analysis of porcine cardiac tissue at graft rejection reveals dysregulation of the key molecules and signaling pathways, which play relevant roles on structural and functional integrities of the heart.

Reduced release of vasoconstrictors from the porcine heart after repeated periods of ischemia

2005 ◽  
Vol 39 (1-2) ◽  
pp. 60-66 ◽  
Author(s):  
Arnfinn Ilebekk ◽  
Trude Aspelin ◽  
Morten Eriksen ◽  
Anne Larsen ◽  
Torstein Lyberg
Keyword(s):  
Porcine Heart

Phosphofructokinase from porcine heart, liver and erythrocytes

1989 ◽  
Vol 93 (3) ◽  
pp. 517-521
Author(s):  
Takashi Koyama ◽  
Takao Ema ◽  
Naoki Hashizume ◽  
Akira Hachimori ◽  
Eisaku Iizuka
Keyword(s):  
Porcine Heart

pH controlled accelerated dynamic in vitro calcification study of porcine heart valve bioprostheses

2006 ◽  
Vol 39 ◽  
pp. S307
Author(s):  
C.-F. Koening ◽  
M. Krings ◽  
D. Mavrilas ◽  
B. Glasmacher
Keyword(s):  
Heart Valve ◽  
Porcine Heart ◽  
Ph Controlled

scholarly journals P-083 Comparison of lesion volumes after radio-frequency ablation with platinum-iridium and gold electrode in the porcine heart

EP Europace ◽  
2003 ◽  
Vol 4 (Supplement_2) ◽  
pp. B86-B86
Author(s):  
A. Bitzen ◽  
A. Yang ◽  
J. Schrickel ◽  
J.O. Schwab ◽  
H. Bielik ◽  
...  
Keyword(s):  
Radio Frequency ◽  
Gold Electrode ◽  
Radio Frequency Ablation ◽  
Porcine Heart
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