Surgical Management of Deep-Seated Cerebrovascular Lesions by Means of Temporary Vascular Occlusion Using Sendai Cocktail

Author(s):  
J. Suzuki ◽  
T. Kayama ◽  
T. Yoshimoto
Blood ◽  
2009 ◽  
Vol 114 (22) ◽  
pp. 4612-4612
Author(s):  
Ana Claudia C Leite ◽  
Orlando CG Veloso ◽  
Clarisse Lopes de Castro Lobo ◽  
Raquel VC Oliveira ◽  
Paulo RV Bahia

Abstract Abstract 4612 Silent infarcts have been reported in approximately 20% of children with SCD. The prevalence in SCD adult patients has not been studied previously. METHODS We studied 187 patients (mean age 29 years) Each of these patients underwent a neurological examination, duplex scan of carotids and TCD image with atoxic contrast (micro bubbles). Eighty of these patients were sorted to perform MRI and MRA to study lacunar infarction, encephalomalacia, leukoencephalopathy, Moya Moya syndrome and aneurysm (measured by number and size). RESULTS The overall prevalence of silent infarcts was 52%. Comparing the two methods regarding sensitivity and specificity, obtained respectively 88 and 85%. The positive predictive value of the TCD image with contrast was 80%. There was only one case of intracranial aneurysm, observed by both imaging methods. The other asymptomatic patients with abnormal TCD (low definition of image contrast or absence of flow to TCD image) presented diagnostic criteria of vascular occlusion with secondary collateral (Moya Moya Syndrome). CONCLUSIONS Use of atoxic contrast (micro bubbles) increases the sensitivity of TCD image for diagnosis of intracranial lesions in SCD adults patients, even in asymptomatic individuals, enabling the diagnosis of silent infarcts. Disclosures: No relevant conflicts of interest to declare.


2019 ◽  
Vol 4 (5) ◽  
pp. 857-869
Author(s):  
Oksana A. Jackson ◽  
Alison E. Kaye

Purpose The purpose of this tutorial was to describe the surgical management of palate-related abnormalities associated with 22q11.2 deletion syndrome. Craniofacial differences in 22q11.2 deletion syndrome may include overt or occult clefting of the palate and/or lip along with oropharyngeal variances that may lead to velopharyngeal dysfunction. This chapter will describe these circumstances, including incidence, diagnosis, and indications for surgical intervention. Speech assessment and imaging of the velopharyngeal system will be discussed as it relates to preoperative evaluation and surgical decision making. Important for patients with 22q11.2 deletion syndrome is appropriate preoperative screening to assess for internal carotid artery positioning, cervical spine abnormalities, and obstructive sleep apnea. Timing of surgery as well as different techniques, common complications, and outcomes will also be discussed. Conclusion Management of velopharyngeal dysfunction in patients with 22q11.2 deletion syndrome is challenging and requires thoughtful preoperative assessment and planning as well as a careful surgical technique.


2001 ◽  
Vol 120 (5) ◽  
pp. A401-A401 ◽  
Author(s):  
D EFRON ◽  
K LILLEMOE ◽  
J CAMERON ◽  
S TIERNEY ◽  
S ABRAHAM ◽  
...  

1962 ◽  
Vol 42 (3) ◽  
pp. 233-243 ◽  
Author(s):  
Frederic W. Smith ◽  
David H. Law ◽  
William F. Nickel ◽  
Marvin H. Sleisenger

2006 ◽  
Vol 175 (4S) ◽  
pp. 112-112
Author(s):  
Jennifer T. Anger ◽  
Mark S. Litwin ◽  
Qin Wang ◽  
Er Chen ◽  
Chris L. Pashos ◽  
...  

2006 ◽  
Vol 175 (4S) ◽  
pp. 549-549 ◽  
Author(s):  
Charles D. Scales ◽  
David Kang ◽  
Ravi Munver ◽  
Brian K. Auge ◽  
Wesley Ekeruo ◽  
...  

2005 ◽  
Vol 173 (4S) ◽  
pp. 20-21 ◽  
Author(s):  
Mohamad E. Allaf ◽  
Ioannis M. Varkarakis ◽  
Edward M. Schaeffer ◽  
Sam B. Bhayani ◽  
Richard E. Link ◽  
...  

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