Brain Edema Induced by Ventricular Puncture. A Study by Magnetic Resonance Imaging

Magnetic resonance imaging has been used for evaluating of a brain edema in experimental animals to assess cytotoxic and vasogenic edema by the apparent diffusion coefficient (ADC) and T2 imaging. This paper brings information about the effectiveness of methylprednisolone (MP) on experimental brain edema. A total of 24 rats were divided into three groups of 8 animals each. Rats with cytotoxic/intracellular brain edema induced by water intoxication were assigned to the group WI. These rats also served as the additional control group CG when measured before the induction of edema. A third group (WIMP) was intraperitoneally administered with methylprednisolone 100 mg/kg during water intoxication treatment. The group WI+MP was injected with methylprednisolone 50 mg/kg into the carotid artery within two hours after the water intoxication treatment. We evaluated the results in four groups. Two control groups (CG, WI) and two experimental groups (WIMP, WI+MP). Rats were subjected to MR scanning 24 h after edema induction. We observed significantly increased ADC values in group WI in both evaluated areas – cortex and hippocampus, which proved the occurrence of experimental vasogenic edema, while ADC values in groups WIMP and WI+MP were not increased, indicating that the experimental edema was not developed and thus confirming the protective effect of MP.

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Magnetic Resonance Imaging Studies with Cluster Algorithm for Characterization of Brain Edema after Controlled Cortical Impact Injury (CCII)

Intracranial Pressure and Neuromonitoring in Brain Injury ◽

10.1007/978-3-7091-6475-4_88 ◽

1998 ◽

pp. 303-305 ◽

Cited By ~ 2

Author(s):

Ralf Stroop ◽

U. W. Thomale ◽

S. Päuser ◽

J. Bernarding ◽

W. Vollmann ◽

...

Keyword(s):

Magnetic Resonance Imaging ◽

Magnetic Resonance ◽

Brain Edema ◽

Cluster Algorithm ◽

Resonance Imaging ◽

Imaging Studies ◽

Controlled Cortical Impact ◽

Controlled Cortical Impact Injury ◽

Impact Injury

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Magnetic resonance imaging measurement of brain edema in patients with liver disease: resolution after transplantation

Current Opinion in Neurology ◽

10.1097/01.wco.0000044771.39452.8d ◽

2002 ◽

Vol 15 (6) ◽

pp. 731-737 ◽

Cited By ~ 6

Author(s):

Alex Rovira ◽

Juan Córdoba ◽

Nuria Raguer ◽

Juli Alonso

Keyword(s):

Magnetic Resonance Imaging ◽

Liver Disease ◽

Magnetic Resonance ◽

Brain Edema ◽

Resonance Imaging ◽

Magnetic Resonance Imaging Measurement

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Peritumoral Brain Edema in Intracranial Meningiomas: Effects of Radiological and Histological Factors

Neurosurgery ◽

10.1097/00006123-200111000-00003 ◽

2001 ◽

Vol 49 (5) ◽

pp. 1046-1052 ◽

Cited By ~ 16

Author(s):

Takashi Tamiya ◽

Yasuhiro Ono ◽

Kengo Matsumoto ◽

Takashi Ohmoto

Keyword(s):

Magnetic Resonance Imaging ◽

Relative Risk ◽

Magnetic Resonance ◽

Brain Edema ◽

Blood Supply ◽

Tumor Size ◽

Resonance Imaging ◽

Tumor Vascularity ◽

Intracranial Meningiomas ◽

Peritumoral Brain Edema

ABSTRACT OBJECTIVE We examined the radiological and histological features influencing the development of peritumoral brain edema (PTBE) among patients with meningiomas. METHODS Factors causing PTBE were retrospectively analyzed for 125 patients with primary intracranial meningiomas. These factors included tumor size, tumor location, brain-tumor interface, signal intensity on T2-weighted scans, contrast enhancement, and cyst formation (as observed on magnetic resonance imaging scans), as well as tumor vascularity and blood supply (as observed in digital subtraction angiography studies). We defined the edema/tumor volume ratio as the edema index, and we used this index to evaluate PTBE. RESULTS A relationship between the tumor size and the volume of PTBE was observed. Convexity and middle fossa meningiomas demonstrated the greatest increases in mean edema indices. Meningothelial, anaplastic, microcystic, and angiomatous subtypes exhibited higher edema indices than did other types. Multivariate analysis demonstrated two significant radiological factors: cortical penetration (as defined by the disappearance of the arachnoid layer on magnetic resonance imaging scans) (relative risk, 2.067;P = 0.0148) and vascular supply from the pial-cortical arteries (as observed on angiograms) (relative risk, 2.087;P = 0.0082). CONCLUSION Tumor infiltration into adjacent brain parenchyma and a pial-cortical blood supply are critical factors for the development of PTBE among patients with meningiomas.

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