Expression of the β-Amyloid Precursor Protein Gene and the Pathogenesis of Alzheimer’s Disease

Basic and Clinical Aspects of Neuroscience - Regulation of Gene Expression and Brain Function ◽

10.1007/978-3-642-78458-3_5 ◽

1994 ◽

pp. 47-56 ◽

Author(s):

Paul J. Harrison

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Amyloid Precursor Protein ◽

Protein Gene ◽

Precursor Protein ◽

Amyloid Precursor Protein Gene ◽

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Early-onset Alzheimer's disease caused by mutations at codon 717 of the β-amyloid precursor protein gene

Nature ◽

10.1038/353844a0 ◽

1991 ◽

Vol 353 (6347) ◽

pp. 844-846 ◽

Author(s):

Marie-Christine Chartier-Harlin ◽

Fiona Crawford ◽

Henry Houlden ◽

Andrew Warren ◽

David Hughes ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Amyloid Precursor Protein ◽

Early Onset ◽

Protein Gene ◽

Precursor Protein ◽

Amyloid Precursor Protein Gene ◽

Early Onset Alzheimer’S Disease ◽

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Polymorphic tetranucleotide repeat site within intron 7 of the β-amyloid precursor protein gene and its lack of association with Alzheimer's disease

Human Genetics ◽

10.1007/s004390050788 ◽

1998 ◽

Vol 103 (1) ◽

pp. 86-89 ◽

Author(s):

Ling Li ◽

Rodney Perry ◽

Jianming Wu ◽

D. Pham ◽

Tauni Ohman ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Amyloid Precursor Protein ◽

Protein Gene ◽

Precursor Protein ◽

Amyloid Precursor Protein Gene ◽

Tetranucleotide Repeat ◽

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Sequencing of exons 16 and 17 of the β-amyloid precursor protein gene in 14 families with early onset Alzheimer's disease fails to reveal mutations in the β-amyloid sequence

Neuroscience Letters ◽

10.1016/0304-3940(91)90042-r ◽

1991 ◽

Vol 133 (1) ◽

pp. 1-2 ◽

Author(s):

Fiona Crawford ◽

John Hardy ◽

Mike Mullan ◽

Alison Goate ◽

David Hughes ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Amyloid Precursor Protein ◽

Early Onset ◽

Protein Gene ◽

Precursor Protein ◽

Amyloid Precursor Protein Gene ◽

Early Onset Alzheimer’S Disease ◽

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A discussion of the significance of mutations in the β-amyloid precursor protein gene as one cause of Alzheimer's disease

Neurobiology of Aging ◽

10.1016/0197-4580(92)90381-7 ◽

1992 ◽

Vol 13 ◽

pp. S64-S65

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Amyloid Precursor Protein ◽

Protein Gene ◽

Precursor Protein ◽

Amyloid Precursor Protein Gene ◽

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Sequencing of exons 16 and 17 of the β-amyloid precursor protein gene fails to identify new mutations in Swedish Alzheimer's disease patients

Human Molecular Genetics ◽

10.1093/hmg/2.7.1045 ◽

1993 ◽

Vol 2 (7) ◽

pp. 1045-1046 ◽

Author(s):

Janet Johnston ◽

Lena Lillus ◽

Karin Axelman ◽

Richard Cowburn ◽

Kurt Johansson ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Amyloid Precursor Protein ◽

Protein Gene ◽

Precursor Protein ◽

Amyloid Precursor Protein Gene ◽

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Sequence analysis of amyloid precursor protein gene in Alzheimer's disease: Consensus sequences associated with alternative splicing of exons 7 and 8

Neurobiology of Aging ◽

10.1016/0197-4580(94)92991-2 ◽

1994 ◽

Vol 15 ◽

pp. S131

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Alternative Splicing ◽

Sequence Analysis ◽

Amyloid Precursor Protein ◽

Protein Gene ◽

Precursor Protein ◽

Amyloid Precursor Protein Gene ◽

Consensus Sequences

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Clinical characteristics in a kindred with early-onset Alzheimer's disease and their linkage to a G->T change at position 2149 of the amyloid precursor protein gene

Neurology ◽

10.1212/wnl.44.1.105 ◽

1994 ◽

Vol 44 (1) ◽

pp. 105-105 ◽

Author(s):

M. Farlow ◽

J. Murrell ◽

B. Ghetti ◽

F. Unverzagt ◽

S. Zeldenrust ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Amyloid Precursor Protein ◽

Early Onset ◽

Clinical Characteristics ◽

Protein Gene ◽

Precursor Protein ◽

Amyloid Precursor Protein Gene ◽

Early Onset Alzheimer’S Disease

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Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease

Nature ◽

10.1038/349704a0 ◽

1991 ◽

Vol 349 (6311) ◽

pp. 704-706 ◽

Cited By ~ 2882

Author(s):

Alison Goate ◽

Marie-Christine Chartier-Harlin ◽

Mike Mullan ◽

Jeremy Brown ◽

Fiona Crawford ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Amyloid Precursor Protein ◽

Missense Mutation ◽

Protein Gene ◽

Precursor Protein ◽

Amyloid Precursor Protein Gene ◽

Familial Alzheimer’S Disease ◽

Familial Alzheimer's Disease

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356 Clinical and pathological findings in a family with early onset Alzheimer's disease and cerebral haemorrhage linked to the β-amyloid precursor protein gene

Neurobiology of Aging ◽

10.1016/s0197-4580(96)80358-7 ◽

1996 ◽

Vol 17 (4) ◽

pp. S89

Author(s):

F. van Harskamp ◽

C.M. van Duyn ◽

L. Hendriks ◽

P. Cras ◽

J.M. Kros ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Amyloid Precursor Protein ◽

Early Onset ◽

Protein Gene ◽

Cerebral Haemorrhage ◽

Precursor Protein ◽

Amyloid Precursor Protein Gene ◽

Pathological Findings ◽

Early Onset Alzheimer’S Disease ◽

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Screening of amyloid precursor protein gene mutation (APP 717 Val → Ile) in Swedisch families with Alzheimer's disease

Journal of Neural Transmission - Parkinsons Disease and Dementia Section ◽

10.1007/bf02261009 ◽

1993 ◽

Vol 6 (2) ◽

pp. 151-156 ◽

Author(s):

E. Almqvist ◽

S. Lake ◽

K. Axelman ◽

K. Johansson ◽

B. Winblad

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Amyloid Precursor Protein ◽

Gene Mutation ◽

Protein Gene ◽

Precursor Protein ◽

Amyloid Precursor Protein Gene

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