CTL-Assays for Functional Testing of Bispecific Antibody Fragments

Antibody Engineering ◽

10.1007/978-3-662-04605-0_45 ◽

2001 ◽

pp. 653-663

Author(s):

Anja Löffler ◽

Torsten Dreier ◽

Ralf C. Bargou

Keyword(s):

Bispecific Antibody ◽

Antibody Fragments ◽

Functional Testing

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Tumor growth inhibition with bispecific antibody fragments in a syngeneic mouse melanoma model: The role of targeted T-cell costimulation via CD28

Immunology Letters ◽

10.1016/s0165-2478(97)88217-x ◽

1997 ◽

Vol 56 (1-3) ◽

pp. 340

Author(s):

L Hovest

Keyword(s):

T Cell ◽

Tumor Growth ◽

Growth Inhibition ◽

Bispecific Antibody ◽

Antibody Fragments ◽

Tumor Growth Inhibition ◽

Syngeneic Mouse ◽

Mouse Melanoma Model ◽

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[28] Methods for generating multivalent and bispecific antibody fragments

Methods in Enzymology - Applications of Chimeric Genes and Hybrid Proteins Part A: Gene Expression and Protein Purification ◽

10.1016/s0076-6879(00)26070-9 ◽

2000 ◽

pp. 461-479 ◽

Author(s):

Ian Tomlinson ◽

Philipp Holliger

Keyword(s):

Bispecific Antibody ◽

Antibody Fragments

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"Diabodies": small bivalent and bispecific antibody fragments.

Proceedings of the National Academy of Sciences ◽

10.1073/pnas.90.14.6444 ◽

1993 ◽

Vol 90 (14) ◽

pp. 6444-6448 ◽

Author(s):

P. Holliger ◽

T. Prospero ◽

G. Winter

Keyword(s):

Bispecific Antibody ◽

Antibody Fragments

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Phage diabody repertoires for selection of large numbers of bispecific antibody fragments

Nature Biotechnology ◽

10.1038/nbt0996-1149 ◽

1996 ◽

Vol 14 (9) ◽

pp. 1149-1154 ◽

Author(s):

Brian T. McGuinness ◽

Gerald Walter ◽

Kevin FitzGerald ◽

Paula Schuler ◽

Walt Mahoney ◽

...

Keyword(s):

Bispecific Antibody ◽

Antibody Fragments ◽

Large Numbers ◽

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New protein engineering approaches to multivalent and bispecific antibody fragments

Immunotechnology ◽

10.1016/s1380-2933(97)00067-5 ◽

1997 ◽

Vol 3 (2) ◽

pp. 83-105 ◽

Author(s):

Andreas Plückthun ◽

Peter Pack

Keyword(s):

Protein Engineering ◽

Bispecific Antibody ◽

Antibody Fragments ◽

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Fab-scFv fusion protein: an efficient approach to production of bispecific antibody fragments

Journal of Immunological Methods ◽

10.1016/s0022-1759(02)00148-5 ◽

2002 ◽

Vol 267 (2) ◽

pp. 213-226 ◽

Author(s):

Dan Lu ◽

Xenia Jimenez ◽

Haifan Zhang ◽

Peter Bohlen ◽

Larry Witte ◽

...

Keyword(s):

Fusion Protein ◽

Bispecific Antibody ◽

Antibody Fragments ◽

Efficient Approach

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Tumor growth inhibition with bispecific antibody fragments in a syngeneic mouse melanoma model: The role of targeted T-cell costimulation via CD28

Immunology Letters ◽

10.1016/s0165-2478(97)86379-1 ◽

1997 ◽

Vol 56 ◽

pp. 340

Author(s):

L. Große Hovest ◽

W. Marwan ◽

K. Bauer ◽

R. Mocikat ◽

M. Dohlsten ◽

...

Keyword(s):

T Cell ◽

Tumor Growth ◽

Growth Inhibition ◽

Bispecific Antibody ◽

Antibody Fragments ◽

Tumor Growth Inhibition ◽

Syngeneic Mouse ◽

Mouse Melanoma Model ◽

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Bispecific antibody fragments with CD20 × CD28 specificity allow effective autologous and allogeneic T-cell activation against malignant cells in peripheral blood and bone marrow cultures from patients with B-cell lineage leukemia and lymphoma

Experimental Hematology ◽

10.1016/s0301-472x(99)00072-7 ◽

1999 ◽

Vol 27 (8) ◽

pp. 1264-1270 ◽

Author(s):

Martina Brandl ◽

Ludger Große-Hovest ◽

Ernst Holler ◽

Hans-Jochem Kolb ◽

Gundram Jung

Keyword(s):

Bone Marrow ◽

B Cell ◽

T Cell Activation ◽

Cell Activation ◽

Bispecific Antibody ◽

Cell Lineage ◽

Antibody Fragments ◽

Malignant Cells ◽

Bone Marrow Cultures ◽

Marrow Cultures

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Diabodies: small bispecific antibody fragments

Cancer Immunology Immunotherapy ◽

10.1007/s002620050414 ◽

1997 ◽

Vol 45 (3-4) ◽

pp. 128-130 ◽

Author(s):

P. Holliger ◽

Greg Winter

Keyword(s):

Bispecific Antibody ◽

Antibody Fragments

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Construction of diabody phage display repertories for the selection of large numbers of bispecific antibody fragments [Abst. 217]

Immunotechnology ◽

10.1016/s1380-2933(97)89046-x ◽

1996 ◽

Vol 2 (4) ◽

pp. 288

Keyword(s):

Phage Display ◽

Bispecific Antibody ◽

Antibody Fragments ◽

Large Numbers ◽

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