Left Ventricular Fibrosis in Patients with Aortic Stenosis

2019 ◽  
pp. 127-139
Author(s):  
Vassilis S. Vassiliou ◽  
Calvin W. L. Chin ◽  
Tamir Malley ◽  
David E. Newby ◽  
Marc R. Dweck ◽  
...  
Keyword(s):  
Aortic Stenosis ◽  
Left Ventricular ◽  
Ventricular Fibrosis

scholarly journals Myocardial and circulating levels of microRNA-21 reflect left ventricular fibrosis in aortic stenosis patients

2013 ◽  
Vol 167 (6) ◽  
pp. 2875-2881 ◽  
Author(s):  
Ana V. Villar ◽  
Raquel García ◽  
David Merino ◽  
Miguel Llano ◽  
Manuel Cobo ◽  
...  
Keyword(s):  
Aortic Stenosis ◽  
Left Ventricular ◽  
Ventricular Fibrosis ◽  
Circulating Levels

Left Ventricular Hypertrophy in Isolated Aortic Stenosis: Primetime for the Ventricle

2012 ◽  
Vol 13 (13) ◽  
pp. 2503-2514 ◽  
Author(s):  
Cristina Gavina ◽  
Ines Falcao-Pires ◽  
Francisco Rocha-Goncalves ◽  
Adelino Leite-Moreira
Keyword(s):  
Left Ventricular Hypertrophy ◽  
Aortic Stenosis ◽  
Ventricular Hypertrophy ◽  
Left Ventricular

scholarly journals Recovery of left ventricular systolic function in different entities of aortic stenosis 12 months after TAVI

2013 ◽  
Vol 34 (suppl 1) ◽  
pp. P5409-P5409
Author(s):  
S. Spethmann ◽  
G. Baldenhofer ◽  
H. Dreger ◽  
K. Stueer ◽  
E. Mueller ◽  
...  
Keyword(s):  
Aortic Stenosis ◽  
Systolic Function ◽  
Left Ventricular Systolic Function ◽  
Left Ventricular ◽  
Ventricular Systolic Function

Comparison of Aortic Gradient and Ventricular Mass after Valve Replacement for Aortic Stenosis with Rapid Deployment, Sutureless, and Conventional Bioprostheses

Cardiology ◽  
2021 ◽  
pp. 1-11
Author(s):  
Rubén Taboada-Martín ◽  
José María Arribas-Leal ◽  
María Asunción Esteve-Pastor ◽  
José Abellán Alemán ◽  
Francisco Marín ◽  
...  
Keyword(s):  
Aortic Stenosis ◽  
Severe Aortic Stenosis ◽  
Left Ventricular ◽  
Ventricular Mass ◽  
Risk Of Mortality ◽  
Echocardiographic Parameters ◽  
Rapid Deployment ◽  
The Impact ◽  
Peak Gradient

<b><i>Background:</i></b> The use of rapid deployment and sutureless aortic prostheses is increasing. Previous reports have shown promising results on haemodynamic performance and mortality rates. However, the impact of these bioprostheses on left ventricular mass (LVM) regression remains unknown. We decided to study the changes in remodelling and LVM regression in isolated severe aortic stenosis treated with conventional or Perceval® or Intuity® valves. <b><i>Method and Results:</i></b> From January 2011 to January 2016, 324 bioprostheses were implanted in our centre. The collected characteristics were divided into 3 groups: conventional valves, Perceval®, and Intuity®, and they were analysed after 12 months. There were 183 conventional valves (56%), 72 Perceval® (22%), and 69 Intuity® (21.2%). The statistical analysis showed significant differences in transprosthetic postoperative peak gradient (23 [18–29] mm Hg vs. 21 [16–29] mm Hg and 18 [14–24] mm Hg, <i>p</i> &#x3c; 0.001), ventricular mass electrical criteria regression (Sokolow and Cornell products), and 1-year survival (90 vs. 93% and 97%, log rank <i>p</i> value = 0.04) in conventional, Perceval®, and Intuity® groups. <b><i>Conclusions:</i></b> We observed differences in haemodynamic, electrocardiographic, and echocardiographic parameters related to the different types of prosthesis. Patients with the Intuity® prosthesis had the highest reduction in peak aortic gradient and the higher ventricular mass regression. Besides, patients with the Intuity® prosthesis had less risk of mortality during follow-up than the other two groups. Further studies are needed to confirm these findings.

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