Effect of Histamine on the Blood-Tumor Barrier in Transplanted Rat Brain Tumors

1994 ◽  
pp. 400-402 ◽  
Author(s):  
T. Nomura ◽  
Kiyonobu Ikezaki ◽  
K. Matsukado ◽  
M. Fukui
Keyword(s):  
Brain Tumors ◽  
Rat Brain

Quinolinate Immunoreactivity in Experimental Rat Brain Tumors Is Present in Macrophages but Not in Astrocytes

1997 ◽  
Vol 144 (2) ◽  
pp. 287-301 ◽  
Author(s):  
John R. Moffett ◽  
Thomas Els ◽  
Michael G. Espey ◽  
Sharon A. Walter ◽  
Wolfgang J. Streit ◽  
...  
Keyword(s):  
Brain Tumors ◽  
Rat Brain

scholarly journals Tissue Distribution of Water-soluble Pheophorbide-a in Experimental Rat Brain Tumors

1993 ◽  
Vol 14 (Supplement) ◽  
pp. 329-332
Author(s):  
Shuji Monden ◽  
Tohru Uozumi ◽  
Takashi Yano
Keyword(s):  
Brain Tumors ◽  
Tissue Distribution ◽  
Rat Brain ◽  
Water Soluble ◽  
Pheophorbide A

31-P-NMR Spectroscopy in vivo of Human and Rat Brain Tumors Grafted on Nude Mice

1987 ◽  
pp. 381-384
Author(s):  
C. Remy ◽  
J. P. Albrand ◽  
S. Lotito ◽  
M. Jacrot ◽  
A. François ◽  
...  
Keyword(s):  
Nmr Spectroscopy ◽  
Brain Tumors ◽  
Rat Brain ◽  
Nude Mice

DNA synthesis, blood flow, and glucose utilization in experimental rat brain tumors

1989 ◽  
Vol 70 (1) ◽  
pp. 86-91 ◽  
Author(s):  
Akira Watanabe ◽  
Ryuichi Tanaka ◽  
Norio Takeda ◽  
Kazuo Washiyama
Keyword(s):  
Blood Flow ◽  
Brain Tumors ◽  
Rat Brain ◽  
Glucose Utilization ◽  
Acid Synthesis ◽  
S Phase ◽  
Immunoperoxidase Staining ◽  
Content Type ◽  
Contralateral Cortex ◽  
Autoradiographic Technique

✓ The relationships between distribution of deoxyribonucleic acid (DNA)-synthesizing cells (S-phase cells) and blood flow and glucose utilization were investigated in rat brain tumors using an autoradiographic technique and immunoperoxidase staining for bromodeoxyuridine (BUdR). Two strains of rat brain tumor were used: strain A and B, both induced by the Rous sarcoma virus. Strain A was biologically more malignant than strain B. The blood flow was unevenly distributed in the tumor; compared with the contralateral cortex, the average blood flow in the tumor was about 50% in strain A and 60% in strain B. The distribution of blood flow did not correlate with the distribution of S-phase cells or with the distribution of vessels in the tumor in either strain A or B. The average glucose utilization in strain A was about 250% and in strain B about 170% of that of the contralateral cortex. The high glucose utilization area correlated well with the distribution of BUdR-positive nuclei in strain B. These findings suggest that the biological malignancy of a tumor correlates with glucose utilization rather than with blood flow, and that malignant brain tumors show a marked increase in glucose utilization for nucleic acid synthesis.

scholarly journals Biochemical Changes in Experimental Rat Brain Tumors Induced by Ethylnitrosourea and Human Gliomas after Dibutyryl Cyclic AMP Treatment

1982 ◽  
Vol 22 (1) ◽  
pp. 1-6 ◽  
Author(s):  
Iekado SHIBATA ◽  
Mikiro MATSUMOTO ◽  
Sadatsugu NAGASAWA ◽  
Yoshikatsu SEIKI ◽  
Junichi TAKEZAWA
Keyword(s):  
Cyclic Amp ◽  
Brain Tumors ◽  
Rat Brain ◽  
Biochemical Changes ◽  
Dibutyryl Cyclic Amp ◽  
Human Gliomas

Selective ablation of rat brain tumors by boron neutron capture therapy

1994 ◽  
Vol 28 (5) ◽  
pp. 1067-1077 ◽  
Author(s):  
Jeffrey Coderre ◽  
Philip Rubin ◽  
Alan Freedman ◽  
John Hansen ◽  
Thomas S. Wooding ◽  
...  
Keyword(s):  
Brain Tumors ◽  
Rat Brain ◽  
Boron Neutron Capture Therapy ◽  
Neutron Capture ◽  
Neutron Capture Therapy ◽  
Boron Neutron Capture ◽  
Selective Ablation
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