Brittle Bones and Frequent Fractures

2015 ◽  
pp. 299-310
Author(s):  
Benjamin Joseph
Keyword(s):  
Brittle Bones

A novel transgenic murine model with persistently brittle bones simulating osteogenesis imperfecta type I

Bone ◽  
2019 ◽  
Vol 127 ◽  
pp. 646-655 ◽  
Author(s):  
Yi Liu ◽  
Jianhai Wang ◽  
Shuo Liu ◽  
Mingjie Kuang ◽  
Yaqing Jing ◽  
...  
Keyword(s):  
Osteogenesis Imperfecta ◽  
Murine Model ◽  
Type I ◽  
Osteogenesis Imperfecta Type ◽  
Transgenic Murine Model ◽  
Brittle Bones ◽  
Osteogenesis Imperfecta Type I

The Association of Blue Sclerotics With Brittle Bones and Progressive Deafness

QJM ◽  
1924 ◽  
Vol os-17 (67) ◽  
pp. 274-287 ◽  
Author(s):  
W. Stobie
Keyword(s):  
Brittle Bones

scholarly journals BLUE SCLEROTICS AND BRITTLE BONES, WITH MACULAR ATROPHY OF THE SKIN AND ZONULAR CATARACT

BMJ ◽  
1921 ◽  
Vol 2 (3182) ◽  
pp. 1071-1072 ◽  
Author(s):  
O. Blegvad ◽  
H. Haxthausen
Keyword(s):  
Macular Atrophy ◽  
Brittle Bones

BIOMEDICINE: Brittle Bones

Science ◽  
2009 ◽  
Vol 323 (5920) ◽  
pp. 1406c-1406c
Author(s):  
V. Vinson
Keyword(s):  
Brittle Bones

scholarly journals A Roadmap to the Brittle Bones of Cystic Fibrosis

2011 ◽  
Vol 2011 ◽  
pp. 1-10 ◽  
Author(s):  
Ashwini P. Gore ◽  
Soon Ho Kwon ◽  
Antine E. Stenbit
Keyword(s):  
Cystic Fibrosis ◽  
Lung Transplantation ◽  
Bone Disease ◽  
Bone Health ◽  
Autosomal Recessive ◽  
Multidisciplinary Approach ◽  
Early Recognition ◽  
Autosomal Recessive Disorder ◽  
Fatal Disease ◽  
Brittle Bones

Cystic fibrosis (CF) is an autosomal recessive disorder which despite advances in medical care continues to be a life-limiting and often fatal disease. With increase in life expectancy of the CF population, bone disease has emerged as a common complication. Unlike the osteoporosis seen in postmenopausal population, bone disease in CF begins at a young age and is associated with significant morbidity due to fractures, kyphosis, increased pain, and decreased lung function. The maintenance of bone health is essential for the CF population during their lives to prevent pain and fractures but also as they approach lung transplantation since severe bone disease can lead to exclusion from lung transplantation. Early recognition, prevention, and treatment are key to maintaining optimal bone health in CF patients and often require a multidisciplinary approach. This article will review the pathophysiology, current clinical practice guidelines, and potential future therapies for treating CF-related bone disease.

BLUE SCLEROTICS AND BRITTLE BONES

JAMA ◽  
1924 ◽  
Vol 83 (9) ◽  
pp. 689
Keyword(s):  
Brittle Bones

scholarly journals BLUE SCLEROTICS AND BRITTLE BONES

BMJ ◽  
1911 ◽  
Vol 2 (2635) ◽  
pp. 16-16 ◽  
Author(s):  
H. Burrows
Keyword(s):  
Brittle Bones
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