Endemic (Balkan) Nephropathy: A Disease Caused by Aristolochic Acid

2012 ◽  
pp. 219-227
Author(s):  
Bojan Jelaković ◽  
Živka Dika ◽  
Arthur P. Grollman
Keyword(s):  
Aristolochic Acid ◽  
Balkan Nephropathy

scholarly journals Aristolochic acid and the etiology of endemic (Balkan) nephropathy

2007 ◽  
Vol 104 (29) ◽  
pp. 12129-12134 ◽  
Author(s):  
A. P. Grollman ◽  
S. Shibutani ◽  
M. Moriya ◽  
F. Miller ◽  
L. Wu ◽  
...  
Keyword(s):  
Aristolochic Acid ◽  
Balkan Nephropathy

Abstract 1837: Exposure to Aristolochic Acid is associated with endemic (Balkan) nephropathy

2010 ◽  
Author(s):  
Karen L. Edwards ◽  
Jia Yin Wang ◽  
Katherine Snappin ◽  
Zdenko Sonicki ◽  
Marcia Miletic-Medved ◽  
...  
Keyword(s):  
Aristolochic Acid ◽  
Balkan Nephropathy

Lupane Type Triterpene Isolated from the Leaves of Thecacoris Annobonea (Euphorbiaceae)

2013 ◽  
Vol 12 (10) ◽  
pp. 695-701
Author(s):  
Herve Martial Poumale Poumale ◽  
Alphonsine Nkapwa Guedem ◽  
Louis Pergaud Sandjo ◽  
Bonaventure Tchaleu Ngadjui ◽  
Yoshihito Shiono
Keyword(s):  
Antimicrobial Activity ◽  
Root Growth ◽  
Betulinic Acid ◽  
Aristolochic Acid ◽  
2D Nmr ◽  
Aristolochic Acid I

A new lupane type triterpene (1), together with betulinic acid (2), friedelin (3), aristolochic acid I (4), alpinumisoflavone (5) and 4’-O-methylepinumisoflavone (6) have been isolated from the leaves of Thecacoris annobonea. The structure of the new compound was elucidated on the basis of 1 and 2D NMR experiments. The isolated compounds were evaluated for their phytotoxicity and antimicrobial activity. 1 exhibited significant antimicrobial activity at 30 μg/ml and compounds 1, 2, 3, 4, 5 and 6 inhibited root growth lettuce at 100 μg/ml. 

Enzymes Metabolizing Aristolochic Acid and their Contribution to the Development of Aristolochic Acid Nephropathy and Urothelial Cancer

2013 ◽  
Vol 14 (6) ◽  
pp. 695-705 ◽  
Author(s):  
Marie Stiborova ◽  
Vaclav Martínek ◽  
Eva Frei ◽  
Volker Arlt ◽  
Heinz Schmeiser
Keyword(s):  
Urothelial Cancer ◽  
Aristolochic Acid ◽  
Aristolochic Acid Nephropathy
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