Regulations/Ethical Guidelines on Human Adult/Mesenchymal Stem Cell Clinical Trial and Clinical Translation

Author(s):  
Xiaomei Zhai ◽  
Renzong Qiu
Author(s):  
Marie Maumus ◽  
Pauline Rozier ◽  
Jérémy Boulestreau ◽  
Christian Jorgensen ◽  
Danièle Noël

2014 ◽  
Vol 7 (2) ◽  
pp. 118-126 ◽  
Author(s):  
Masoud Maleki ◽  
Farideh Ghanbarvand ◽  
Mohammad Reza Behvarz ◽  
Mehri Ejtemaei ◽  
Elham Ghadirkhomi

2019 ◽  
Vol 14 (1) ◽  
pp. 22-33 ◽  
Author(s):  
Ali Golchin ◽  
Tahereh Z. Farahany ◽  
Arash Khojasteh ◽  
Fatemeh Soleimanifar ◽  
Abdolreza Ardeshirylajimi

The skin is one of the crucial body organs with anatomy and physiology linked to various disorders including congenital and acquired diseases. Nowadays, mesenchymal stem cell (MSCs)- based therapy has appeared as a promising therapeutic field, in which many see opportunities to cure the costliest and incurable diseases. However, one question to be asked is that if the use of MSCs in clinical trials studies and diseases treatment has improved. In this study, the clinical trials using MSCs in skin diseases were reviewed. A remarkable number of clinical trial studies are in progress in this field; however, only a few of them have led to tangible benefits for patients. The relevant papers and ongoing clinical trials that address MSC’s therapeutic goals for various skin disorders were examined. This review can be very useful for both the dermatologists and basic skin researchers interested in contributing to stem cell-based therapeutic researches in the area of skin disorders.


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