Developmental Physiology of the Gastrointestinal Tract and Feed Intolerance in Preterm Neonates

Author(s):  
Sanjay Patole
2020 ◽  
Vol 7 (2) ◽  
pp. 248
Author(s):  
Jyoti B. Sarvi ◽  
Sandeep V. H.

Background: Late preterm birth (34-36 weeks) infants are at greater risk of (2-3 fold) compared to near term or term babies. The present study was done with the purpose to examine related morbidities and outcomes among late preterm infants.Methods: The study included all late preterm babies (34 0/7 weeks-36 6/7 weeks) admitted to the Basaveshwar Teaching and General Hospital and Sangameshwar Hospital for a period of one and half year (December 2013-May 2015). Short term outcome was assessed in the form of neonatal morbidities and mortality during the study period.Results: A total of 203 late Preterm neonates comprised the study group. Male preponderance was noticed with a ratio of 1.5:1. This study confirmed that late-preterm infants are a population at risk of increased neonatal morbidity. Neonatal hyperbilirubinemia requiring phototherapy forms the major one followed by sepsis, respiratory distress, and feed intolerance. Majority of late preterm neonates required more than 7 days hospital duration.Conclusions: Late preterm infants suffer a large number of intercurrent medical problems during the neonatal period, especially increased likelihood of resuscitation in the delivery room, hypothermia, hypoglycemia, jaundice requiring phototherapy, respiratory pathologies, sepsis and feeding intolerance. Prolonging pregnancy to the maximum safest gestation will result in decrease in such morbidities.


2021 ◽  
Vol 10 (Suppl 1) ◽  
pp. e001439
Author(s):  
Abhishek S Aradhya ◽  
Inderjot Kaur ◽  
Rima Gupta ◽  
Sonaljot Kaur ◽  
Yamasandi Siddegowda Shrimanth ◽  
...  

BackgroundA three-hourly feeding schedule has been shown to be as safe as a two-hourly schedule in preterm neonates. It saves nursing time and may be less tiring for the mothers. However, tradition and apprehensions have prevented its wider acceptance. We used a quality improvement approach to implement a three-hourly feeding schedule in stable preterm infants >32 weeks postmenstrual age (PMA) in our unit through a series of plan–do–study–act (PDSA) cycles.MethodsAll preterm neonates >32 weeks PMA, who were on full enteral feeds and without any respiratory support were eligible. The key quantitative outcome was maternal fatigue score. Safety was assessed in terms of episodes of hypoglycaemia and feed intolerance. Qualitative experiences from nursing staff were captured. The volume of expressed breastmilk and requirement of formula feeds were also recorded. After recording baseline data on a two-hourly feeding schedule, four PDSA cycles were sequentially completed over 21 weeks. The results of each PDSA cycle informed the change strategy for the next cycle.ResultsIn the baseline phase, five neonates on a two-hourly schedule were studied. In PDSA cycles I, II, III and IV, a cumulative of 122 neonates were studied on a three-hourly schedule. There was a significant decrease in median maternal fatigue score (13 (IQR 8–23) to 3 (IQR 1–6); p=0.01)). Only one neonate had feed intolerance, while two had mild asymptomatic transient hypoglycaemia. Six (5%) neonates were shifted to two-hourly feeds temporarily due to transient reasons. Nursing staff felt mothers could devote more time to Kangaroo mother care. The volume of expressed breastmilk and requirement of formula feeds were not different from the three-hourly schedule.ConclusionsIt was possible to change the traditional two-hourly feeding schedule to three-hourly in stable preterm infants using a quality improvement approach, while objectively documenting its safety and benefits.


2007 ◽  
Vol 93 (4) ◽  
pp. F265-F270 ◽  
Author(s):  
V R Kairamkonda ◽  
A Deorukhkar ◽  
C Bruce ◽  
R Coombs ◽  
R Fraser ◽  
...  

2020 ◽  
pp. 164-190
Author(s):  
Peter N. Bromley ◽  
Ellen Rawlinson ◽  
Zoe Harclerode ◽  
James Bennett

2018 ◽  
Vol 33 (11) ◽  
pp. 1846-1852
Author(s):  
Abhishek Somasekhara Aradhya ◽  
Kanya Mukhopadhyay ◽  
Shiv Sajan Saini ◽  
Venkataseshan Sundaram ◽  
Sourabh Dutta ◽  
...  

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