Cyclosporin A and skin disease

Cyclosporin ◽  
1989 ◽  
pp. 191-212 ◽  
Author(s):  
Anne V. Powles ◽  
Barbara S. Baker ◽  
Lionel Fry
Keyword(s):  
Cyclosporin A ◽  
Skin Disease

Paracrystalline Aggregates of Psoriatic Keratin and Their Relation to Normal Keratin Structure

1985 ◽  
Vol 43 ◽  
pp. 680-681
Author(s):  
S. Trachtenberg ◽  
P.M. Steinert ◽  
B.L. Trus ◽  
A.C. Steven
Keyword(s):  
Cell Death ◽  
Stratum Corneum ◽  
Intermediate Filament ◽  
Skin Disease ◽  
Amorphous Matrix ◽  
Terminal Differentiation ◽  
Proteolytic Degradation ◽  
Horny Layer ◽  
Chronic Skin ◽  
Chronic Skin Disease

During terminal differentiation of vertebrate epidermis, certain specific keratin intermediate filament (KIF) proteins are produced. Keratinization of the epidermis involves cell death and disruption of the cytoplasm, leaving a network of KIF embedded in an amorphous matrix which forms the outer horny layer known as the stratum corneum. Eventually these cells are shed (desquamation). Normally, the processes of differentiation, keratinization, and desquamation are regulated in an orderly manner. In psoriasis, a chronic skin disease, a hyperkeratotic stratum corneum is produced, resulting in abnormal desquamation of unusually large scales. In this disease, the normal KIF proteins are diminished in amount or absent, and other proteins more typical of proliferative epidermal cells are present. There is also evidence of proteolytic degradation of the KIF.

Changes in CD44 isoform expression during inflammatory skin disease

1997 ◽  
Vol 22 (03) ◽  
pp. 128-133
Author(s):  
A.J. HARRIS ◽  
D. DEAN ◽  
S. BURGE ◽  
F. WOJNAROWSKA
Keyword(s):  
Skin Disease ◽  
Inflammatory Skin Disease ◽  
Inflammatory Skin ◽  
Isoform Expression

Magnetic resonance imaging of renal transplants: its value in the differentiation of acute rejection and cyclosporin a nephrotoxicity

1988 ◽  
Vol 39 (2) ◽  
pp. 220-228
Author(s):  
L TESTRAKE ◽  
L SCHULTZEKOOL ◽  
L PAUL ◽  
A TEGZESS ◽  
J WEENINGS ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Acute Rejection ◽  
Cyclosporin A ◽  
Resonance Imaging ◽  
Renal Transplants

1869: Combined Therapy of FR167653 and Cyclosporin A Significantly Prolonged Animal Survival in ratRenal Allografts

2004 ◽  
Vol 171 (4S) ◽  
pp. 493-494
Author(s):  
Haruhito Azuma ◽  
Shiro Takahara ◽  
Takashi Wada ◽  
Takeshi Sakamoto ◽  
Akihiko Okuyama ◽  
...  
Keyword(s):  
Cyclosporin A ◽  
Combined Therapy ◽  
Animal Survival

The skin disease that cures itself

Nature ◽  
2010 ◽  
Author(s):  
Ewen Callaway
Keyword(s):  
Skin Disease
Sign in / Sign up

Export Citation Format

Share Document