On the Prognosis of Liver Cirrhosis

Author(s):  
M. Burghardt ◽  
A. Henze ◽  
U. Russmann ◽  
J. Lobers ◽  
E. Schmidt ◽  
...  
2003 ◽  
Vol 18 (6) ◽  
pp. 833 ◽  
Author(s):  
Young Sun Kim ◽  
Soon Ho Um ◽  
Ho Sang Ryu ◽  
Jung Bok Lee ◽  
Jae Won Lee ◽  
...  

2020 ◽  
Vol 7 (2) ◽  
pp. 122-129
Author(s):  
Adelia Muhlifa Saputri ◽  
Magdaleni Agustina Rahayu ◽  
Sinta Murti

Liver cirrhosis is the last stage of chronic liver disease that is in the path of the disease can cause damage of liver function and/or portal hypertension. The prognosis of liver cirrhosis can be assessed by manifestations of liver function disorders with Child Pugh score that include the presence or absence of ascites, encephalopathy, bilirubin serum, albumin serum, and prothrombin time or INR, while portal hypertension also occurs in patient of cirrhosis can lead the formation of esophageal varices. APRI score has platelet count and AST serum as its variable is suspected to be related to the Child Pugh score in assessing prognosis of cirrhosis patients. This study purposed to find the relation between APRI score (Aspartate Aminotransferase-to-Platelet Ratio Index) and Child Pugh score. Purpose of this research is to find the relation between APRI score (Aspartate Aminotransferase-to-Platelet Ratio Index) and Child Pugh score and degree of esophageal varices in patients with cirrhosis. Method used is a retrospective analytic study with cross sectional approach. The data source is secondary source. The sample in this study were patients with liver cirrhosis who were diagnosed by a doctor and had complied the inclusion criteria. The data obtained was analyzed using ANOVA. The result of this study is include 48 cirrhosis patients, male 81,3%, with a mean age 49,98 years. The most common cause of cirrhosis is hepatitis B obtained from reactive HBsAg examination in 33 patients (68,8%). The APRI score was found to have a weak correlation (r = 0.044) and not significant (p = 0.868) with the Child Pugh score. The APRI score do not able to assess the prognosis in advanced cirrhotic patients.


2014 ◽  
Vol 23 (2) ◽  
pp. 215-218 ◽  
Author(s):  
Secil Omer ◽  
Octavian Zara ◽  
Claudia Iacobescu ◽  
Ion Dina

The prognosis of liver cirrhosis depends on the presence of its major complications as well as on other factors such as hypersplenism with thrombocytopenia. Partial splenic embolization is an effective interventional procedure performed in liver cirrhosis complicated with portal hypertension to improve the low platelet count. This technique represents an efficient alternative to splenectomy, which has major drawbacks and is associated with a high morbidity. We report a series of patients with liver cirrhosis and portal hypertension who presented with severe thrombocytopenia and were treated with partial splenic embolization eventually having a favourable outcome.


2020 ◽  
Vol 2020 ◽  
pp. 1-10
Author(s):  
Si-Hai Chen ◽  
Qin-Si Wan ◽  
Ting Wang ◽  
Kun-He Zhang

Liver cirrhosis is the terminal stage of most chronic liver conditions, with a high risk of mortality. Careful evaluation of the prognosis of cirrhotic patients and providing precise management are crucial to reduce the risk of mortality. Although the liver biopsy and hepatic venous pressure gradient (HVPG) can efficiently evaluate the prognosis of cirrhotic patients, their application is limited due to the invasion procedures. Child-Pugh score and the model for end-stage liver disease (MELD) score had been widely used in the assessment of cirrhotic prognosis, but the defects of subjective variable application in Child-Pugh score and unsuitability to all phases of liver cirrhosis in MELD score limit their prognostic values. In recent years, continuous efforts have been made to investigate the prognostic value of body fluid biomarkers for cirrhotic patients, and promising results have been reported. Since the collection of fluid specimens is easy, noninvasive, and repeatable, fluid biomarkers can be ideal indicators to predict the prognosis of cirrhosis. Here, we reviewed noninvasive fluid biomarkers in different prognostic functions, including the prediction of survival and complication development.


Author(s):  
Lider Olmen Panggabean ◽  
Gontar Alamsyah Siregar ◽  
Masrul Lubis

Background: Child-Pugh score is used to predict the poor prognosis of liver cirrhosis patients. The study objectives analyzed differences in inflammatory parameters of Child-Pugh B and Child-Pugh C of liver cirrhosis with hepatorenal syndrome. Method: Desain's study is cross-sectional in liver cirrhosis patients with hepatorenal syndrome.  This research was approved by the Health Research Ethics Commission FK USU / RSUP H. Adam Malik Medan and meets the criteria of inclusion or exclusion. Diagnosis of Liver cirrhosis Child-Pugh B and Child-Pugh C score is done by clinical examination, laboratory, and ultrasound, CT scan, MRI. The hepatorenal syndrome was diagnosed using Criteria International Ascites Club, 2007. Results: The sample number of this study was 26 liver cirrhosis with hepatorenal syndrome patients consisting of Child-Pugh B patients 9 patients and Child-Pugh C patients 17  patients. The comparison between Child-Pugh B and Child-Pugh C has significant differences in leukocyte, Na, Cl, SGOT, and CTP. There is a significant correlation between CTP and leukocytes, platelets, Cl, creatinine, GFR, albumin, total bilirubin, and glued bilirubin. Conclusion: There is no clear difference in the inflammatory parameters of the Child-Pug B and Child-Pug C scores in liver cirrhosis with hepatorenal syndrome.


Metallomics ◽  
2015 ◽  
Vol 7 (3) ◽  
pp. 491-498 ◽  
Author(s):  
Marta Costas-Rodríguez ◽  
Yulia Anoshkina ◽  
Sara Lauwens ◽  
Hans Van Vlierberghe ◽  
Joris Delanghe ◽  
...  

The isotopic composition of blood serum Cu has been investigated as a potential parameter for the diagnosis and prognosis of liver cirrhosis.


Sign in / Sign up

Export Citation Format

Share Document