Enzyme regulation by reversible phosphorylation: the neural and hormonal control of cellular activity

1983 ◽  
pp. 42-71 ◽  
Author(s):  
Philip Cohen
Keyword(s):  
Enzyme Regulation ◽  
Hormonal Control ◽  
Cellular Activity ◽  
Reversible Phosphorylation

scholarly journals The role of reversible phosphorylation in the hormonal control of phenylalanine hydroxylase in isolated rat proximal kidney tubules

1993 ◽  
Vol 292 (2) ◽  
pp. 419-424 ◽  
Author(s):  
S C B Richardson ◽  
R A Aspbury ◽  
M J Fisher
Keyword(s):  
Phenylalanine Hydroxylase ◽  
Enzymic Activity ◽  
Hormonal Control ◽  
Kidney Tubules ◽  
Reversible Phosphorylation ◽  
Proximal Tubule Cells ◽  
Major Mechanism ◽  
The Impact ◽  
First Time ◽  
Isolated Rat

Reversible phosphorylation is the major mechanism underlying the short-term hormonal control of phenylalanine hydroxylase activity in the liver. We report here, for the first time, the impact of a range of hormonal effectors on both the phosphorylation state and enzymic activity of phenylalanine hydroxylase present in isolated rat proximal kidney tubules. The most potent stimulator of enzyme phosphorylation was found to be parathyroid hormone, which is known to stimulate the production of cyclic AMP in proximal-tubule cells. In addition, adrenergic amines also stimulated enzyme phosphorylation, although to a lesser extent, through interaction with a mixed alpha 1 and beta receptor population.

The effects of Cyclosporin-A (CYA) on the Ultrastructure of Gingival Mast Cells (GMC) in Behcet's disease (BD)

1990 ◽  
Vol 48 (3) ◽  
pp. 358-359
Author(s):  
Oktay Arda ◽  
Ulkü Noyan ◽  
Selgçk Yilmaz ◽  
Mustafa Taşyürekli ◽  
İsmail Seçkin ◽  
...  
Keyword(s):  
Unknown Etiology ◽  
Control Group ◽  
Target Cells ◽  
Gingival Hyperplasia ◽  
Cellular Activity ◽  
Direct Relation ◽  
Immune Disease ◽  
Genital Ulceration ◽  
Functional Changes ◽  
The Third

Turkish dermatologist, H. Beheet described the disease as recurrent triad of iritis, oral aphthous lesions and genital ulceration. Auto immune disease is the recent focus on the unknown etiology which is still being discussed. Among the other immunosupressive drugs, CyA included in it's treatment newly. One of the important side effects of this drug is gingival hyperplasia which has a direct relation with the presence of teeth and periodontal tissue. We are interested in the ultrastructure of immunocompetent target cells that were affected by CyA in BD.Three groups arranged in each having 5 patients with BD. Control group was the first and didn’t have CyA treatment. Patients who had CyA, but didn’t show gingival hyperplasia assembled the second group. The ones displaying gingival hyperplasia following CyA therapy formed the third group. GMC of control group and their granules are shown in FIG. 1,2,3. GMC of the second group presented initiation of supplementary cellular activity and possible maturing functional changes with the signs of increased number of mitochondria and accumulation of numerous dense cored granules next to few normal ones, FIG. 4,5,6.

Hormonal control of ketogenesis. Biochemical considerations

1977 ◽  
Vol 137 (4) ◽  
pp. 495-501 ◽  
Author(s):  
J. D. McGarry
Keyword(s):  
Hormonal Control

The cellular activity of cucurbitacin I is inhibited by glycosylation

Planta Medica ◽  
2014 ◽  
Vol 80 (16) ◽  
Author(s):  
MS Hassoun ◽  
MJ Clément ◽  
M Cailleret ◽  
N Jarroux ◽  
I Hamdi ◽  
...  
Keyword(s):  
Cellular Activity
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