Spatio-Temporal Directional Analysis of Real-Time Three Dimensional Cardiac Ultrasound

2001 ◽  
pp. 379-416 ◽  
Author(s):  
Elsa Angelini ◽  
Andrew Laine
Keyword(s):  
Real Time ◽  
Three Dimensional ◽  
Cardiac Ultrasound ◽  
Directional Analysis ◽  
Spatio Temporal

scholarly journals A novel localization based biosensor, SEDAR, visualizes spatio-temporal dynamics of activated Ras in endogenous Drosophila tissues

2018 ◽  
Author(s):  
Rishita Changede
Keyword(s):  
Plasma Membrane ◽  
Growth Factor ◽  
Real Time ◽  
Tyrosine Kinases ◽  
Temporal Dynamics ◽  
Three Dimensional ◽  
Growth Factor Receptor ◽  
Leading Edge ◽  
Border Cells ◽  
Spatio Temporal

AbstractChemokine signaling via growth factor receptor tyrosine kinases (RTKs) regulates development, differentiation, growth and disease implying that it is involved in a myriad of cellular processes. A single RTK, for example the Epidermal Growth Factor Receptor (EGFR), is used repeatedly for a multitude of developmental programs. Quantitative differences in magnitude and duration of RTK signaling can bring about different signaling outcomes. Understanding this complex RTK signals requires real time visualization of the signal. To visualize spatio-temporal signaling dynamics, a biosensor called SEnsitive Detection of Activated Ras (SEDAR) was developed. It is a localization-based sensor that binds to activated Ras directly downstream of the endogenous activated RTKs. This binding was reversible and SEDAR expression did not cause any detectable perturbation of the endogenous signal. Using SEDAR, endogenous guidance signaling was visualized during RTK mediated chemotaxis of border cells in Drosophila ovary. SEDAR localized to both the leading and rear end of the cluster but polarized at the leading edge of the cluster. Perturbation of RTKs that led to delays in forward migration of the cluster correlated with loss of SEDAR polarization in the cluster. Gliding or tumbling behavior of border cells was a directly related to the high or low magnitude of SEDAR polarization respectively, in the leading cell showing that signal polarization at the plasma membrane provided information for the migratory behavior. Further, SEDAR localization to the plasma membrane detected EGFR mediated signaling in five distinct developmental contexts. Hence SEDAR, a novel biosensor could be used as a valuable tool to study the dynamics of endogenous Ras activation in real time downstream of RTKs, in three-dimensional tissues, at an unprecedented spatial and temporal resolution.

scholarly journals Real-Time Map Matching: A New Algorithm Integrating Spatio-Temporal Proximity and Improved Weighted Circle

2019 ◽  
Vol 11 (1) ◽  
pp. 288-297 ◽  
Author(s):  
Wenxin Teng ◽  
Yanhui Wang
Keyword(s):  
Real Time ◽  
Three Dimensional ◽  
Navigation Systems ◽  
Map Matching ◽  
Test Results ◽  
Matching Accuracy ◽  
Optimal Matching ◽  
Temporal Proximity ◽  
Time Map ◽  
Spatio Temporal

Abstract Previous real-time map matching algorithms for in-vehicle navigation systems had some efficiencies and defects on time lagging and low accuracy. As a response, this paper proposes a new algorithm that integrates STP (spatio-temporal proximity) and IWC (improved weighted circle), in which the new algorithm proposes STP to dynamically refine candidate matching roads, and IWC to adaptively identify the optimal matching road. Specifically, three spatio-temporal proximity indicators are defined in STP to build a three-dimensional stereoscopic cone, and then the two-dimensional projection of the cone are adopted to dynamically select the candidate matching roads. Further, by adaptively setting the weight, the IWC algorithm is developed to integrate three new parameters to adaptively determine the optimal matching road. The test results show that the matching accuracy of the algorithm is over 95%, much higher than that of the existing algorithm, which demonstrates the feasibility and efficiency of the new algorithm.

IMPROVED ASSESSMENT OF CARDIAC TUMORS WITH REAL-TIME THREE-DIMENSIONAL ECHOCARDIOGRAPHY

2005 ◽  
Vol 26 (S 1) ◽  
Author(s):  
T Le Tourneau ◽  
B Gal ◽  
A Polge ◽  
V Rachenne ◽  
S Marechaux ◽  
...  
Keyword(s):  
Real Time ◽  
Three Dimensional ◽  
Cardiac Tumors ◽  
Dimensional Echocardiography ◽  
Three Dimensional Echocardiography

Evaluation of the mitral valve by transthoracic real-time three-dimensional echocardiography

2010 ◽  
Vol 151 (21) ◽  
pp. 854-863 ◽  
Author(s):  
Attila Nemes ◽  
Marcel L. Geleijnse ◽  
Osama I. I. Soliman ◽  
Wim B. Vletter ◽  
Jackie S. McGhie ◽  
...  
Keyword(s):  
Mitral Valve ◽  
Real Time ◽  
Three Dimensional ◽  
Dimensional Echocardiography ◽  
Three Dimensional Echocardiography

Jelenleg az echokardiográfia a legszéleskörűbben alkalmazott rutin noninvazív diagnosztikus eljárás, amelynek segítségével a mitralis billentyű morfológiája és funkciója jellemezhető. Ennek az összefoglaló jellegű közleménynek a célja az egyik legújabb echokardiográfiás fejlesztés, a transthoracalis real-time háromdimenziós echokardiográfia szerepének bemutatása a mitralis billentyű vizsgálatában.

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