scholarly journals Clinical Case Vignettes: Vasculitis

2016 ◽  
pp. 535-541
Author(s):  
Anju Gupta ◽  
P. Vignesh
Keyword(s):  
2010 ◽  
Vol 4 (1) ◽  
pp. 31-38 ◽  
Author(s):  
Jeff C. Huffman ◽  
Oliver Freudenreich ◽  
Sarah Romeo ◽  
Lee Baer ◽  
Kelly Sutton-Skinner ◽  
...  

2010 ◽  
Vol 34 (6) ◽  
pp. 445-448 ◽  
Author(s):  
J. C. Huffman ◽  
T. Petersen ◽  
L. Baer ◽  
S. Romeo ◽  
K. Sutton-Skinner ◽  
...  

PLoS ONE ◽  
2015 ◽  
Vol 10 (9) ◽  
pp. e0138663 ◽  
Author(s):  
Anne Rousseau ◽  
Patrick Rozenberg ◽  
Philippe Ravaud

2016 ◽  
Vol 41 (3) ◽  
pp. 364-368 ◽  
Author(s):  
Gillian L. Sowden ◽  
Heather S. Vestal ◽  
Joseph B. Stoklosa ◽  
Stephanie C. Valcourt ◽  
John W. Peabody ◽  
...  

Stroke ◽  
2015 ◽  
Vol 46 (suppl_1) ◽  
Author(s):  
Marie Luby ◽  
Steven J Warach ◽  
Gregory W Albers ◽  
Christophe Cognard ◽  
Geoffrey A Donnan ◽  
...  

Background and Purpose: To quantify consistency across stroke centers worldwide in the typical imaging and treatment decisions made when presented with independent clinical case vignettes including various imaging findings across specific time from onset intervals. Methods: Stroke Imaging Repository (STIR) and Virtual International Stroke Trials Archive (VISTA)-Imaging circulated an online survey of clinical case vignettes through its website, through the websites of national professional societies from multiple countries as well as through email distribution lists from STIR and participating societies. Vignettes varied in terms of patient’s age, time from onset, neurological symptoms and NIHSS. The survey displayed the imaging findings offered by the imaging strategy selected, and the responders selected the appropriate therapy considering time from onset, clinical presentation and imaging findings. Results: We received responses from 30 countries including 260 centers. The specific onset interval presented: 0-3 hours, 6 hours, 10 hours or wake-up, influenced the type of imaging work-up selected rather than the clinical scenario. CT was used more often than MRI across all time intervals. For cases with M1 occlusion and large penumbra, vascular imaging was most common (36%) in 0-3 hours and perfusion imaging more frequently used in 6 hours (62%) and wake-up stroke (65%). For large penumbra cases with M1 or ICA occlusion, combination, IV tPA thrombolysis followed by endovascular\IA, treatment (81%) was most common in 0-3 hours. Endovascular treatment was selected the most at 6 hours (43%) for M1 occlusion and large penumbra cases but still selected in 27% of patients up to 10 hours for ICA occlusion and large penumbra cases. For M1 occlusion and large penumbra cases imaged with MRI only, treatment of wake-up stroke increased to 89% from 58% cases imaged with CT alone. Sites that obtained more imaging tended to be more aggressive in terms of revascularization treatment, particularly endovascular therapy. Conclusions: Adding vascular and\or perfusion imaging increased the likelihood of thrombolysis across all time intervals. Usage of MRI perfusion imaging was associated with an increased likelihood of enrollment into a randomized trial up to 83%.


2020 ◽  
Vol 31 (6) ◽  
pp. 1153-1161
Author(s):  
Jil Billy Mamza ◽  
Rebecca Geary ◽  
Dina El-Hamamsy ◽  
Ipek Gurol ◽  
Jonathan Duckett ◽  
...  

Autism ◽  
2020 ◽  
Vol 24 (7) ◽  
pp. 1885-1897
Author(s):  
Magali Barnoux ◽  
Regi Alexander ◽  
Sabyasachi Bhaumik ◽  
John Devapriam ◽  
Connor Duggan ◽  
...  

Autistic adults who have a history of committing crimes present a major problem for providers of services in terms of legal disposal options and possible interventions, and greater understanding of this group and their associated needs is required. For this reason, we aimed to investigate the face validity of a proposed sub-typology of autistic adults detained in secure psychiatric hospitals in the United Kingdom. Initially, a focus group was completed with psychiatrists, clinical psychologists, healthcare workers, family members and autistic adults who had been detained in hospital, leading to revisions of the sub-typology. Following this, a consensus rating exercise of 10 clinical vignettes based on this sub-typology with three rounds was completed with 15 psychiatrists and clinical psychologists; revisions to the vignettes to improve clarity were made following each round. The findings indicated that these subtypes possess face validity and raters were able to classify all 10 clinical case vignettes into the sub-typology, and percentage of agreement ranged from 96% to 100% for overall subtype classification. This study suggests that the further validity of the sub-typology should be investigated within a larger study, as these subtypes have the potential to directly inform the hospital care pathway such that length of stay can be minimised. Lay abstract Autistic adults who have a history of committing crimes pose challenges for the criminal justice system in terms of disposal and treatment. For this reason, we investigated the validity of a proposed sub-typology of autistic adults detained in secure psychiatric hospitals. Initially, we ran a focus group with psychiatrists, clinical psychologists, healthcare workers, family members and autistic adults who had been detained in hospital to consider a sub-typology of autistic adults who may come into contact with secure psychiatric hospitals. We asked 15 psychiatrists and clinical psychologists to rate 10 clinical vignettes based on our sub-typology with three rounds; revisions to the vignettes to improve clarity were made following each round. The findings indicated that these subtypes possess face validity and raters were able to classify all 10 clinical case vignettes into the sub-typology and percentage of agreement ranged from 96% to 100% for overall subtype classification. The findings suggested that the further validity of the sub-typology should be investigated within a larger study using a clinical sample. These subtypes may help inform treatment and care pathways within hospital.


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