Cell Therapy for Ischemic Heart Disease

2017 ◽  
pp. 81-98
Author(s):  
Hiroshi Kurazumi ◽  
Tohru Hosoyama ◽  
Kimikazu Hamano
Keyword(s):  
Heart Disease ◽  
Cell Therapy ◽  
Ischemic Heart Disease ◽  
Ischemic Heart

scholarly journals Cell Therapy in Ischemic Heart Disease: Interventions That Modulate Cardiac Regeneration

2016 ◽  
Vol 2016 ◽  
pp. 1-16 ◽  
Author(s):  
Maximiliano I. Schaun ◽  
Bruna Eibel ◽  
Melissa Kristocheck ◽  
Grasiele Sausen ◽  
Luana Machado ◽  
...  
Keyword(s):  
Heart Disease ◽  
Cell Therapy ◽  
Ischemic Heart Disease ◽  
Adult Stem Cells ◽  
Therapeutic Potential ◽  
Cardiac Regeneration ◽  
Current Data ◽  
Ischemic Heart ◽  
Promising Alternative ◽  
Clinical Conditions

The incidence of severe ischemic heart disease caused by coronary obstruction has progressively increased. Alternative forms of treatment have been studied in an attempt to regenerate myocardial tissue, induce angiogenesis, and improve clinical conditions. In this context, cell therapy has emerged as a promising alternative using cells with regenerative potential, focusing on the release of paracrine and autocrine factors that contribute to cell survival, angiogenesis, and tissue remodeling. Evidence of the safety, feasibility, and potential effectiveness of cell therapy has emerged from several clinical trials using different lineages of adult stem cells. The clinical benefit, however, is not yet well established. In this review, we discuss the therapeutic potential of cell therapy in terms of regenerative and angiogenic capacity after myocardial ischemia. In addition, we addressed nonpharmacological interventions that may influence this therapeutic practice, such as diet and physical training. This review brings together current data on pharmacological and nonpharmacological approaches to improve cell homing and cardiac repair.

Similar effect of autologous and allogeneic cell therapy for ischemic heart disease: results from a meta-analysis of large animal studies

2013 ◽  
Vol 34 (suppl 1) ◽  
pp. P1462-P1462
Author(s):  
S. J. Jansen Of Lorkeers ◽  
J. E. C. Eding ◽  
T. I. G. Van Der Spoel ◽  
H. M. Vesterinen ◽  
S. Koudstaal ◽  
...  
Keyword(s):  
Heart Disease ◽  
Cell Therapy ◽  
Ischemic Heart Disease ◽  
Animal Studies ◽  
Meta Analysis ◽  
Ischemic Heart ◽  
Large Animal ◽  
Allogeneic Cell ◽  
Allogeneic Cell Therapy

New strategies for improving stem cell therapy in ischemic heart disease

2016 ◽  
Vol 21 (6) ◽  
pp. 737-752 ◽  
Author(s):  
Peisen Huang ◽  
Xiaqiu Tian ◽  
Qing Li ◽  
Yuejin Yang
Keyword(s):  
Stem Cell ◽  
Heart Disease ◽  
Cell Therapy ◽  
Ischemic Heart Disease ◽  
Stem Cell Therapy ◽  
Ischemic Heart ◽  
New Strategies

Bone Marrow Cell Therapy for Ischemic Heart Disease

2015 ◽  
Vol 117 (6) ◽  
pp. 490-493 ◽  
Author(s):  
Giulio Pompilio ◽  
Patrizia Nigro ◽  
Beatrice Bassetti ◽  
Maurizio C. Capogrossi
Keyword(s):  
Bone Marrow ◽  
Heart Disease ◽  
Cell Therapy ◽  
Ischemic Heart Disease ◽  
Bone Marrow Cell ◽  
Marrow Cell ◽  
Ischemic Heart ◽  
Bone Marrow Cell Therapy

Mixed Results for Bone Marrow–Derived Cell Therapy for Ischemic Heart Disease

JAMA ◽  
2012 ◽  
Vol 308 (22) ◽  
pp. 2405 ◽  
Author(s):  
Eduardo Marbán ◽  
Konstantinos Malliaras
Keyword(s):  
Bone Marrow ◽  
Heart Disease ◽  
Cell Therapy ◽  
Ischemic Heart Disease ◽  
Ischemic Heart

scholarly journals Quantification of Myocardial Segmental Function in Acute and Chronic Ischemic Heart Disease and Implications for Cardiovascular Cell Therapy Trials

2011 ◽  
Vol 4 (6) ◽  
pp. 671-679 ◽  
Author(s):  
John W. Petersen ◽  
John R. Forder ◽  
James D. Thomas ◽  
Lemuel A. Moyé ◽  
Mark Lawson ◽  
...  
Keyword(s):  
Heart Disease ◽  
Cell Therapy ◽  
Ischemic Heart Disease ◽  
Ischemic Heart ◽  
Chronic Ischemic Heart Disease ◽  
Segmental Function

Stem cell therapy in ischemic heart disease

2006 ◽  
Vol 21 (4) ◽  
pp. 327-342 ◽  
Author(s):  
Julia N. E. Sunkomat ◽  
Mohamed A. Gaballa
Keyword(s):  
Stem Cell ◽  
Heart Disease ◽  
Cell Therapy ◽  
Ischemic Heart Disease ◽  
Stem Cell Therapy ◽  
Ischemic Heart

scholarly journals Stem Cell Therapy for Ischemic Heart Disease

2010 ◽  
Vol 13 (12) ◽  
pp. 1879-1897 ◽  
Author(s):  
Mohammad Nurulqadr Jameel ◽  
Jianyi Zhang
Keyword(s):  
Stem Cell ◽  
Heart Disease ◽  
Cell Therapy ◽  
Ischemic Heart Disease ◽  
Stem Cell Therapy ◽  
Ischemic Heart
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