Genetic Factors Underlying Treatment Resistance in Psychiatry

2018 ◽  
pp. 33-63
Author(s):  
Eduard Maron ◽  
Chen-Chia Lan ◽  
David Nutt
Keyword(s):  
Genetic Factors ◽  
Treatment Resistance

IDENTIFYING MUTATIONS ENRICHED IN RELAPSED-REFRACTORY DLBCL TO DERIVE GENETIC FACTORS UNDERLYING TREATMENT RESISTANCE

2019 ◽  
Vol 37 ◽  
pp. 35-36 ◽  
Author(s):  
C. Rushton ◽  
M. Alcaide ◽  
M. Cheung ◽  
N. Thomas ◽  
S. Arthur ◽  
...  
Keyword(s):  
Genetic Factors ◽  
Treatment Resistance

Genetic Factors in the Etiology of Duodenal Ulcer

1961 ◽  
Vol 40 (3) ◽  
pp. 371-378 ◽  
Author(s):  
David A. Price Evans
Keyword(s):  
Duodenal Ulcer ◽  
Genetic Factors

Influence of Genetic Factors on Drug-Reinforced Behavior in Animals

1988 ◽  
Author(s):  
Richard A. Meisch ◽  
Frank R. George
Keyword(s):  
Genetic Factors

Which Personality Disorders Reflect Genetic Factors?

1994 ◽  
Author(s):  
J.T. Nigg ◽  
◽  
H.H. Goldsmith
Keyword(s):  
Personality Disorders ◽  
Genetic Factors

Genetic factors influence ethanol-induced uroporphyria inHfe(?/?) mice

Hepatology ◽  
2004 ◽  
Vol 40 (4) ◽  
pp. 942-950 ◽  
Author(s):  
Nadia Gorman ◽  
Heidi W. Trask ◽  
William J. Bement ◽  
Juliana G. Szakacs ◽  
George H. Elder ◽  
...  
Keyword(s):  
Genetic Factors

Genetic Factors May Dictate Course of Knee Osteoarthritis

2008 ◽  
Vol 38 (4) ◽  
pp. 33
Author(s):  
DAMIAN MCNAMARA
Keyword(s):  
Knee Osteoarthritis ◽  
Genetic Factors

Bestimmung der DNA-Schädigung in vitro

2010 ◽  
Vol 49 (S 01) ◽  
pp. S64-S68
Author(s):  
E. Dikomey
Keyword(s):  
Dna Damage ◽  
Cell Lines ◽  
Chromosome Aberrations ◽  
Genetic Factors ◽  
Double Strand Breaks ◽  
Strand Breaks ◽  
Cell Inactivation ◽  
Repair Mechanisms ◽  
Break Repair

SummaryIonising irradiation acts primarily via induction of DNA damage, among which doublestrand breaks are the most important lesions. These lesions may lead to lethal chromosome aberrations, which are the main reason for cell inactivation. Double-strand breaks can be repaired by several different mechanisms. The regulation of these mechanisms appears be fairly different for normal and tumour cells. Among different cell lines capacity of doublestrand break repair varies by only few percents and is known to be determined mostly by genetic factors. Knowledge about doublestrand break repair mechanisms and their regulation is important for the optimal application of ionising irradiation in medicine.

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