Viral Quasispecies Spectrum Reconstruction via Coloring the Vertex in the Weighted Read Conflict Graph

Proceedings of the 2nd International Conference on Healthcare Science and Engineering - Lecture Notes in Electrical Engineering ◽

10.1007/978-981-13-6837-0_1 ◽

2019 ◽

pp. 1-15

Author(s):

Jingli Wu ◽

Dan Huang ◽

Jinyan Wang ◽

Yuanxiu Liao ◽

Jianbo Lu

Keyword(s):

Conflict Graph ◽

Viral Quasispecies ◽

Spectrum Reconstruction

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Interferon therapy in chronic hepatitis C virus infection does not modify complexity of viral quasispecies in nonresponders

Journal of Hepatology ◽

10.1016/s0168-8278(01)80569-9 ◽

2001 ◽

Vol 34 (0) ◽

pp. 156

Author(s):

R Barcena Marugan

Keyword(s):

Chronic Hepatitis ◽

Hepatitis C Virus ◽

Hepatitis C ◽

Virus Infection ◽

Chronic Hepatitis C ◽

Interferon Therapy ◽

Viral Quasispecies ◽

Hepatitis C Virus Infection ◽

Chronic Hepatitis C Virus

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Design of mid-infrared filter array based on plasmonic metal nanodiscs array and its application to on-chip spectrometer

Scientific Reports ◽

10.1038/s41598-021-91762-7 ◽

2021 ◽

Vol 11 (1) ◽

Author(s):

Hwa-Seub Lee ◽

Gyu-Weon Hwang ◽

Tae-Yeon Seong ◽

Jongkil Park ◽

Jae Wook Kim ◽

...

Keyword(s):

Nanoimprint Lithography ◽

Filter Design ◽

Reconstruction Technique ◽

Filter Function ◽

Promising Alternative ◽

Mid Infrared ◽

Spectrum Reconstruction ◽

Filter Array ◽

On Chip ◽

Multispectral Filter Array

AbstractMid-infrared wavelengths are called the molecular fingerprint region because it contains the fundamental vibrational modes inherent to the substances of interest. Since the mid-infrared spectrum can provide non-destructive identification and quantitative analysis of unknown substances, miniaturized mid-infrared spectrometers for on-site diagnosis have attained great concern. Filter-array based on-chip spectrometer has been regarded as a promising alternative. In this study, we explore a way of applying a pillar-type plasmonic nanodiscs array, which is advantageous not only for excellent tunability of resonance wavelength but also for 2-dimensional integration through a single layer process, to the multispectral filter array for the on-chip spectrometer. We theoretically and experimentally investigated the optical properties of multi-periodic triangular lattices of metal nanodiscs array that act as stopband filters in the mid-infrared region. Soft-mold reverse nanoimprint lithography with a subsequent lift-off process was employed to fabricate the multispectral filter array and its filter function was successfully extracted using a Fourier transform infrared microscope. With the measured filter function, we tested the feasibility of target spectrum reconstruction using a Tikhonov regularization method for an ill-posed linear problem and evaluated its applicability to the infrared spectroscopic sensor that monitors an oil condition. These results not only verify that the multispectral filter array composed of stopband filters based on the metal nanodiscs array when combined with the spectrum reconstruction technique, has great potential for use to a miniaturized mid-infrared on-chip spectrometer, but also provide effective guidance for the filter design.

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