Discovery and Development of Stem Cells for Therapeutic Applications

2021 ◽  
pp. 267-296
Author(s):  
Arun H. S. Kumar
Keyword(s):  
Stem Cells ◽  
Therapeutic Applications

scholarly journals Mesenchymal stem cells for therapeutic applications in pulmonary medicine

2015 ◽  
Vol 115 (1) ◽  
pp. 45-56 ◽  
Author(s):  
Collin T. Stabler ◽  
Shimon Lecht ◽  
Philip Lazarovici ◽  
Peter I. Lelkes
Keyword(s):  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Pulmonary Medicine ◽  
Therapeutic Applications

Cardiac Stem Cells: Biology and Therapeutic Applications

2011 ◽  
pp. 327-346 ◽  
Author(s):  
Sarah Selem ◽  
Konstantinos E. Hatzistergos ◽  
Joshua M. Hare
Keyword(s):  
Stem Cells ◽  
Cardiac Stem Cells ◽  
Therapeutic Applications

scholarly journals The Proangiogenic Potential of Mesenchymal Stem Cells and Their Therapeutic Applications

2017 ◽  
Author(s):  
Nadeeka Bandara ◽  
Shiang Lim ◽  
Haiying Chen ◽  
Shuangfeng Chen ◽  
Le-Xin Wang ◽  
...  
Keyword(s):  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Therapeutic Applications

scholarly journals Adult stem cells and their trans-differentiation potential—perspectives and therapeutic applications

2008 ◽  
Vol 86 (12) ◽  
pp. 1301-1314 ◽  
Author(s):  
Sabine Hombach-Klonisch ◽  
Soumya Panigrahi ◽  
Iran Rashedi ◽  
Anja Seifert ◽  
Esteban Alberti ◽  
...  
Keyword(s):  
Stem Cells ◽  
Adult Stem Cells ◽  
Differentiation Potential ◽  
Therapeutic Applications

scholarly journals Human Pluripotent Stem Cell Culture: Current Status, Challenges, and Advancement

2018 ◽  
Vol 2018 ◽  
pp. 1-17 ◽  
Author(s):  
Sushrut Dakhore ◽  
Bhavana Nayer ◽  
Kouichi Hasegawa
Keyword(s):  
Stem Cells ◽  
Cell Culture ◽  
Pluripotent Stem Cells ◽  
Large Scale ◽  
Embryonic Stem ◽  
Current Status ◽  
Specific Cell ◽  
Therapeutic Applications ◽  
Proliferative Ability

Over the past two decades, human embryonic stem cells (hESCs) have gained attention due to their pluripotent and proliferative ability which enables production of almost all cell types in the human body in vitro and makes them an excellent tool to study human embryogenesis and disease, as well as for drug discovery and cell transplantation therapies. Discovery of human-induced pluripotent stem cells (hiPSCs) further expanded therapeutic applications of human pluripotent stem cells (PSCs). hPSCs provide a stable and unlimited original cell source for producing suitable cells and tissues for downstream applications. Therefore, engineering the environment in which these cells are grown, for stable and quality-controlled hPSC maintenance and production, is one of the key factors governing the success of these applications. hPSCs are maintained in a particular niche using specific cell culture components. Ideally, the culture should be free of xenobiotic components to render hPSCs suitable for therapeutic applications. Substantial efforts have been put to identify effective components, and develop culture conditions and protocols, for their large-scale expansion without compromising on quality. In this review, we discuss different media, their components and functions, including specific requirements to maintain the pluripotent and proliferative ability of hPSCs. Understanding the role of culture components would enable the development of appropriate conditions to promote large-scale, quality-controlled expansion of hPSCs thereby increasing their potential applications.

Generation, Characterization, and Potential Therapeutic Applications of Cardiomyocytes from Various Stem Cells

2012 ◽  
Vol 21 (12) ◽  
pp. 2095-2110 ◽  
Author(s):  
Jianfang Liu ◽  
Zhenzhen Zhang ◽  
Yang Liu ◽  
Chengzhi Guo ◽  
Yuehua Gong ◽  
...  
Keyword(s):  
Stem Cells ◽  
Therapeutic Applications
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