Adjuvant Therapy for Colorectal Cancer

2009 ◽  
pp. 605-612
Author(s):  
David E. Beck ◽  
Patricia L. Roberts ◽  
John L. Rombeau ◽  
Michael J. Stamos ◽  
Steven D. Wexner
Keyword(s):  
Colorectal Cancer ◽  
Adjuvant Therapy

scholarly journals Consumption of Lactose, Other FODMAPs and Diarrhoea during Adjuvant 5-Fluorouracil Chemotherapy for Colorectal Cancer

Nutrients ◽  
2020 ◽  
Vol 12 (2) ◽  
pp. 407
Author(s):  
Reetta Holma ◽  
Reijo Laatikainen ◽  
Helena Orell ◽  
Heikki Joensuu ◽  
Katri Peuhkuri ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Adjuvant Therapy ◽  
Gastrointestinal Symptoms ◽  
Mucosal Injury ◽  
Dietary Carbohydrates ◽  
Food Diary ◽  
High Consumption ◽  
Increased Risk ◽  
Symptom Diary ◽  
Low Consumption

Chemotherapy-induced mucosal injury of the small intestine may interfere with the enzymes and transporters responsible for the hydrolysis and absorption of dietary carbohydrates causing diarrhoea, abdominal discomfort and pain. The aim of this study was to investigate the association between the consumption of foods rich in FODMAPs (fermentable oligo-, di- and monosaccharides and polyols) and gastrointestinal symptoms in patients receiving adjuvant therapy for colorectal cancer. The patients (n = 52) filled in a 4-day food diary at baseline and during therapy and kept a symptom diary. The intakes of FODMAP-rich foods were calculated as portions and the intakes were divided into two consumption categories. Patients with high consumption of FODMAP-rich foods had diarrhoea more frequently than those with low consumption (for lactose-rich foods the odds ratio (OR) was 2.63, P = 0.03; and for other FODMAP-rich foods 1.82, P = 0.20). Patients with high consumption of both lactose-rich and other FODMAP-rich foods had an over 4-fold risk of developing diarrhoea as compared to those with low consumption of both (OR, 4.18; P = 0.02). These results were confirmed in multivariate models. Conclusion: Consumption of lactose-rich foods results in an increased risk of diarrhoea during adjuvant therapy for colorectal cancer, especially when the consumption of other FODMAP-rich foods is also high.

ADJUVANT THERAPY OF COLORECTAL CANCER: AN OVERVIEW

1991 ◽  
Vol 61 (1) ◽  
pp. 13-22 ◽  
Author(s):  
Andrew Wirth ◽  
Michael Green ◽  
John R. Zalcberg
Keyword(s):  
Colorectal Cancer ◽  
Adjuvant Therapy

The Role of Adjuvant Therapy After Liver Resection for Colorectal Cancer Metastase

2001 ◽  
Vol 1 (3) ◽  
pp. 154-166 ◽  
Author(s):  
Leyo Ruo ◽  
Ronald P. DeMatteo ◽  
Leslie H. Blumgart
Keyword(s):  
Colorectal Cancer ◽  
Liver Resection ◽  
Adjuvant Therapy

Thermosensitive hydrogels for local delivery of 5-fluorouracil as neoadjuvant or adjuvant therapy in colorectal cancer

2020 ◽  
Vol 157 ◽  
pp. 154-164 ◽  
Author(s):  
Chantal Al Sabbagh ◽  
Johanne Seguin ◽  
Elena Agapova ◽  
Dounia Kramerich ◽  
Vincent Boudy ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Adjuvant Therapy ◽  
Local Delivery ◽  
Thermosensitive Hydrogels
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