Gelatinase A expression and localization in human breast cancers. An in situ hybridization study and immunohistochemical detection using confocal microscopy

1994 ◽  
Vol 424 (6) ◽  
Author(s):  
M. Polette ◽  
N. Gilbert ◽  
B. Nawrocki ◽  
P. Birembaut ◽  
I. Stas ◽  
...  
Keyword(s):  
In Situ Hybridization ◽  
Confocal Microscopy ◽  
Gelatinase A ◽  
Breast Cancers ◽  
Immunohistochemical Detection ◽  
Hybridization Study ◽  
Human Breast

The numerical aberrations of chromosome 7 detected by fluorescence in situ hybridization in human breast cancers

1993 ◽  
Vol 43 (12) ◽  
pp. 730-735
Author(s):  
Naoki Yoshimi ◽  
Chiken Shibuya ◽  
Yukio Morishita ◽  
Takuji Tanaka ◽  
Hideki Mori
Keyword(s):  
In Situ Hybridization ◽  
Fluorescence In Situ Hybridization ◽  
Chromosome 7 ◽  
Breast Cancers ◽  
Human Breast ◽  
Numerical Aberrations

Expression and distribution of TGFβ mRNA isoforms in a small group of human breast cancers examined by in situ hybridization

The Breast ◽  
1995 ◽  
Vol 4 (4) ◽  
pp. 289-296 ◽  
Author(s):  
J. MacCallum ◽  
R. Poulsom ◽  
A.M. Hanby ◽  
W.R. Miller
Keyword(s):  
In Situ Hybridization ◽  
Small Group ◽  
Breast Cancers ◽  
Human Breast ◽  
Mrna Isoforms

scholarly journals Tumor Collagenase Stimulatory Factor (TCSF) Expression and Localization in Human Lung and Breast Cancers

1997 ◽  
Vol 45 (5) ◽  
pp. 703-709 ◽  
Author(s):  
Myriam Polette ◽  
Christine Gilles ◽  
Veronique Marchand ◽  
Marianne Lorenzato ◽  
Bryan Toole ◽  
...  
Keyword(s):  
In Situ Hybridization ◽  
Northern Blotting ◽  
Gelatinase A ◽  
Breast Cancers ◽  
Normal Tissues ◽  
Histological Results ◽  
Stimulatory Factor

Tumor cell-derived collagenase stimulatory factor (TCSF) stimulates in vitro the biosynthesis of various matrix metalloproteinases involved in tumor invasion, such as interstitial collagenase, gelatinase A, and stromelysin 1. The expression of TCSF mRNAs was studied in vivo, using in situ hybridization and Northern blotting analysis, in seven normal tissues and in 22 squamous cell carcinomas of the lung, and in seven benign proliferations and in 22 ductal carcinomas of the mammary gland. By in situ hybridization, TCSF mRNAs were detected in 40 of 44 carcinomas, in pre-invasive and invasive cancer cells of both lung and breast cancers. TCSF mRNAs and gelatinase A mRNAs were both visualized in the same areas in serial sections in breast cancers, and were expressed by different cells, tumor cells, and fibroblasts. The histological results were confirmed by Northern blot analysis, which showed a higher expression of TCSF mRNAs in cancers than in benign and normal tissues. These observations support the hypothesis that TCSF is an important factor in lung and breast tumor progression.

scholarly journals Distinctive patterns of Her-2/neu, c-myc, and cyclin D1 gene amplification by fluorescence in situ hybridization in primary human breast cancers

Cytometry ◽  
2001 ◽  
Vol 46 (3) ◽  
pp. 136-149 ◽  
Author(s):  
Laura E. Janocko ◽  
Kathryn A. Brown ◽  
Charles A. Smith ◽  
Ling Ping Gu ◽  
Agnese A. Pollice ◽  
...  
Keyword(s):  
In Situ Hybridization ◽  
Fluorescence In Situ Hybridization ◽  
Cyclin D1 ◽  
Gene Amplification ◽  
Breast Cancers ◽  
Human Breast ◽  
Her 2 ◽  
Primary Human Breast
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