Autologous responses to human leukaemic cells in mixed leucocyte culture

1986 ◽  
Vol 22 (2) ◽  
Author(s):  
LeonieK. Ashman ◽  
DeniseE. O'Keefe ◽  
ChristopherA. Juttner ◽  
R.G. Toogood ◽  
MichaelS. Rice
Keyword(s):  
Leucocyte Culture ◽  
Leukaemic Cells

Myeloid leukaemic cells can lyse fibrin directly

2000 ◽  
Vol 111 (2) ◽  
pp. 524-529 ◽  
Author(s):  
Linda Robbie ◽  
Susan Berry ◽  
Elaine Moir ◽  
Nuala A. Booth ◽  
Dominic Culligan ◽  
...  
Keyword(s):  
Leukaemic Cells

PREFERENTIAL ELIMINATION OF LEUKAEMIC CELLS BY PORPHYRIN-INDUCED LASER PHOTOSENSITIZATION

1987 ◽  
Vol 48 (C7) ◽  
pp. C7-297-C7-297
Author(s):  
T. AHMED ◽  
S. GINGRICH ◽  
R. DREYFUS ◽  
Z. ARLIN ◽  
J. D. LUTTON ◽  
...  
Keyword(s):  
Leukaemic Cells

The Local Sanarelli-Shwartzman Phenomenon in Rats Induced by Human Leukaemic Cells

1973 ◽  
Vol 29 (02) ◽  
pp. 353-362
Author(s):  
J Lisiewicz ◽  
A Pituch ◽  
J. A Litwin
Keyword(s):  
Chronic Lymphocytic Leukaemia ◽  
Intravenous Injection ◽  
Peripheral Blood ◽  
Lymphocytic Leukaemia ◽  
Acute Myeloblastic Leukaemia ◽  
Demarcation Line ◽  
E Coli ◽  
Leukaemic Cells ◽  
Shwartzman Phenomenon

SummaryThe local Sanarelli-Shwartzman phenomenon (SSP-L) in the skin of 30 rats was induced by an intr a cutaneous sensitizing injection of leukaemic leucocytes isolated from the peripheral blood of patients with chronic lymphocytic leukaemia (CLL), acute myeloblastic leukaemia (AL) and chronic granulocytic leukaemia (CGL) and challenged by an intravenous injection of 100(μ of E. coli endotoxin. SSP-L was observed in 7 rats after injection of CLL lymphocytes and in 6 and 2 rats after AL myeloblasts and the CGL granulocytes, respectively. The lesions in the skin after AL myeloblasts appeared in a shorter time and were of longer duration compared with those observed after CLL lymphocytes and CGL granulocytes. Histologically, the lesions consisted of areas of destruction in the superficial layers of the skin ; the demarcation line showed the presence of neutrophils, macrophages and erythrocytes. Haemorrhages and fibrin deposits near the demarcation line were larger after injection of CLL lymphocytes and AL myeloblasts than after CGL granulocytes. The possible role of leucocyte procoagulative substances in the differences observed have been discussed.

scholarly journals ABT-199 selectively inhibits BCL2 but not BCL2L1 and efficiently induces apoptosis of chronic lymphocytic leukaemic cells but not platelets

2013 ◽  
Vol 163 (1) ◽  
pp. 139-142 ◽  
Author(s):  
Meike Vogler ◽  
David Dinsdale ◽  
Martin J. S. Dyer ◽  
Gerald M. Cohen
Keyword(s):  
Leukaemic Cells
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