Directionality of phase locking in auditory nerve fibers of the leopard frog Rana pipiens pipiens

1992 ◽  
Vol 170 (5) ◽  
Author(s):  
Barbara Schmilz ◽  
ThomasD. White ◽  
PeterM. Narins
Keyword(s):  
Auditory Nerve ◽  
Rana Pipiens ◽  
Phase Locking ◽  
Nerve Fibers ◽  
Leopard Frog ◽  
Auditory Nerve Fibers ◽  
Rana Pipiens Pipiens

Pathophysiology of Tinnitus

1984 ◽  
Vol 93 (1) ◽  
pp. 39-44 ◽  
Author(s):  
Aage R. Møsller
Keyword(s):  
Auditory Nerve ◽  
Neural Coding ◽  
Temporal Pattern ◽  
Phase Locking ◽  
Cranial Nerves ◽  
Nerve Fibers ◽  
Complex Sounds ◽  
Ephaptic Transmission ◽  
Recent Developments ◽  
Auditory Nerve Fibers

The hypothesis is presented that certain forms of tinnitus are related to abnormal phase-locking of discharges in groups of auditory nerve fibers. Recent developments in auditory neurophysiology have shown that neural coding of the temporal pattern of sounds plays an important role in the analysis of complex sounds. In addition, it has been demonstrated that when some other cranial nerves are damaged, artificial synapses can occur between individual nerve fibers such that ephaptic transmission between nerve fibers is facilitated. Such “crosstalk” between auditory nerve fibers is assumed to result in phase-locking of the spontaneous activity of groups of neurons which in the absence of external sounds creates a neural pattern that resembles that evoked by sounds.

Classification of the temporal discharge patterns of single auditory neurons in the dorsal medullary nucleus of the northern leopard frog

1990 ◽  
Vol 64 (5) ◽  
pp. 1460-1473 ◽  
Author(s):  
J. C. Hall ◽  
A. S. Feng
Keyword(s):  
Auditory Nerve ◽  
Functional Organization ◽  
Neuronal Response ◽  
Nerve Fibers ◽  
Leopard Frog ◽  
Central Auditory Processing ◽  
Acoustic Information ◽  
Auditory Nerve Fibers ◽  
Dorsal Medullary Nucleus ◽  
Discharge Patterns

1. The dorsal medullary nucleus (DMN) of frogs is the presumed homolog of the mammalian cochlear nucleus (CN). Like the CN, the DMN is the sole target of centrally projecting primary auditory-nerve fibers and the first central auditory-processing center. To study the transformation of acoustic information in the DMN, we have utilized relatively simple stimuli--tone bursts--to detail the temporal discharge patterns of DMN neurons that can be compared with those shown by auditory-nerve fibers. 2. Based on the shape of poststimulus time (PSTH) and interspike interval (ISIH) histograms, we observed six distinctive discharge patterns to tone bursts presented at the best excitatory frequency (BEF), 10 dB above threshold. Four of these (primary-like type 1-4) resembled discharge patterns seen at the level of the auditory nerve, whereas two (phasic and phasic burst) were only observed in the DMN. 3. At stimulus levels of 20-30 dB above BEF threshold several phasic neurons became tonic responders, whereas several primary-like type-2 cells gave "pauser" discharges. The response patterns of the remaining cells were intensity independent. 4. We further showed that many of the single-unit discharge patterns were related to other neuronal response properties; specifically, spontaneous firing rate, intensity-rate functions, threshold, latency, BEF, and sharpness of tuning (Q10). 5. The implications of our findings are discussed with respect to 1) the transformation of acoustic information as it is passed from the auditory nerve to the DMN, and 2) the functional organization of the DMN.

Wiener-Kernel Analysis of Responses to Noise of Chinchilla Auditory-Nerve Fibers

2005 ◽  
Vol 93 (6) ◽  
pp. 3615-3634 ◽  
Author(s):  
Alberto Recio-Spinoso ◽  
Andrei N. Temchin ◽  
Pim van Dijk ◽  
Yun-Hui Fan ◽  
Mario A. Ruggero
Keyword(s):  
Auditory Nerve ◽  
Signal To Noise Ratio ◽  
Phase Locking ◽  
Gaussian White Noise ◽  
Nerve Fibers ◽  
Second Order ◽  
First Order ◽  
Auditory Nerve Fibers ◽  
Onset Delays ◽  
Group Delays

Responses to broadband Gaussian white noise were recorded in auditory-nerve fibers of deeply anesthetized chinchillas and analyzed by computation of zeroth-, first-, and second-order Wiener kernels. The first-order kernels (similar to reverse correlations or “revcors”) of fibers with characteristic frequency (CF) <2 kHz consisted of lightly damped transient oscillations with frequency equal to CF. Because of the decay of phase locking strength as a function of frequency, the signal-to-noise ratio of first-order kernels of fibers with CFs >2 kHz decreased with increasing CF at a rate of about −18 dB per octave. However, residual first-order kernels could be detected in fibers with CF as high as 12 kHz. Second-order kernels, 2-dimensional matrices, reveal prominent periodicity at the CF frequency, regardless of CF. Thus onset delays, frequency glides, and near-CF group delays could be estimated for auditory-nerve fibers innervating the entire length of the chinchilla cochlea.

Sign in / Sign up

Export Citation Format

Share Document