Chromosomal inversions and genetic control revisited: the use of inversions in sexing systems for higher Diptera

1991 ◽  
Vol 81 (5) ◽  
pp. 619-623 ◽  
Author(s):  
G. G. Foster
Keyword(s):  
Genetic Control ◽  
Chromosomal Inversions ◽  
Sexing Systems

scholarly journals Exploiting a Y chromosome-linked Cas9 for sex selection and gene drive

2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Stephanie Gamez ◽  
Duverney Chaverra-Rodriguez ◽  
Anna Buchman ◽  
Nikolay P. Kandul ◽  
Stelia C. Mendez-Sanchez ◽  
...  
Keyword(s):  
Genetic Control ◽  
Y Chromosome ◽  
Population Control ◽  
Sex Selection ◽  
Specific Gene ◽  
Gene Drive ◽  
Genetic Sexing ◽  
Animal Populations ◽  
Sexing Systems ◽  
Heterogametic Sex

AbstractCRISPR-based genetic engineering tools aimed to bias sex ratios, or drive effector genes into animal populations, often integrate the transgenes into autosomal chromosomes. However, in species with heterogametic sex chromsomes (e.g. XY, ZW), sex linkage of endonucleases could be beneficial to drive the expression in a sex-specific manner to produce genetic sexing systems, sex ratio distorters, or even sex-specific gene drives, for example. To explore this possibility, here we develop a transgenic line of Drosophila melanogaster expressing Cas9 from the Y chromosome. We functionally characterize the utility of this strain for both sex selection and gene drive finding it to be quite effective. To explore its utility for population control, we built mathematical models illustrating its dynamics as compared to other state-of-the-art systems designed for both population modification and suppression. Taken together, our results contribute to the development of current CRISPR genetic control tools and demonstrate the utility of using sex-linked Cas9 strains for genetic control of animals.

Genetic control of Lepidoptera using genome editing tools

2016 ◽  
Author(s):  
Yong Ping Huang
Keyword(s):  
Genome Editing ◽  
Genetic Control

Genetic Control of DH Reading Frame and Its Effect on B-Cell Development and Antigen-Specifc Antibody Production

2010 ◽  
Vol 30 (4) ◽  
pp. 327-344 ◽  
Author(s):  
Harry W. Schroeder, Jr. ◽  
Michael Zemlin ◽  
Mohamed Khass ◽  
Huan H. Nguyen ◽  
Robert L. Schelonka
Keyword(s):  
B Cell ◽  
Genetic Control ◽  
Antibody Production ◽  
Cell Development ◽  
B Cell Development ◽  
Reading Frame

Genetic control of diabetogenesis in NOD/Lt mice. Development and analysis of congenic stocks

Diabetes ◽  
1989 ◽  
Vol 38 (11) ◽  
pp. 1446-1455 ◽  
Author(s):  
M. Prochazka ◽  
D. V. Serreze ◽  
S. M. Worthen ◽  
E. H. Leiter
Keyword(s):  
Genetic Control

A study of the genetic control of black-red pigment patterns in the fowl

1963 ◽  
Author(s):  
John Albert Brumbaugh
Keyword(s):  
Genetic Control ◽  
Red Pigment ◽  
Pigment Patterns
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