Synaptic plasticity induced in single neurones of the primary somatosensory cortex in vivo

1995 ◽  
Vol 107 (2) ◽  
Author(s):  
PeterM.B. Cahusac
Keyword(s):  
Synaptic Plasticity ◽  
Somatosensory Cortex ◽  
Primary Somatosensory Cortex ◽  
Single Neurones

scholarly journals High-order thalamic inputs to primary somatosensory cortex are stronger and longer lasting than cortical inputs

eLife ◽  
2019 ◽  
Vol 8 ◽  
Author(s):  
Wanying Zhang ◽  
Randy M Bruno
Keyword(s):  
Somatosensory Cortex ◽  
Primary Motor Cortex ◽  
Pyramidal Neurons ◽  
Sensory Stimulation ◽  
Primary Somatosensory Cortex ◽  
Specific Substrate ◽  
Medial Nucleus ◽  
Posterior Medial Nucleus ◽  
Cortical Inputs

Layer (L) 2/3 pyramidal neurons in the primary somatosensory cortex (S1) are sparsely active, spontaneously and during sensory stimulation. Long-range inputs from higher areas may gate L2/3 activity. We investigated their in vivo impact by expressing channelrhodopsin in three main sources of feedback to rat S1: primary motor cortex, secondary somatosensory cortex, and secondary somatosensory thalamic nucleus (the posterior medial nucleus, POm). Inputs from cortical areas were relatively weak. POm, however, more robustly depolarized L2/3 cells and, when paired with peripheral stimulation, evoked action potentials. POm triggered not only a stronger fast-onset depolarization but also a delayed all-or-none persistent depolarization, lasting up to 1 s and exhibiting alpha/beta-range oscillations. Inactivating POm somata abolished persistent but not initial depolarization, indicating a recurrent circuit mechanism. We conclude that secondary thalamus can enhance L2/3 responsiveness over long periods. Such timescales could provide a potential modality-specific substrate for attention, working memory, and plasticity.

scholarly journals The coincident activation of lemniscal and paralemniscal inputs can drive synaptic plasticity in layer 2/3 pyramidal neurons of the mouse somatosensory cortex in vivo

2014 ◽  
Vol 8 ◽  
Author(s):  
Kehayas Vassilis ◽  
Gambino Frédéric ◽  
Baptista Daniela ◽  
Pagès Stéphane ◽  
Holtmaat Anthony
Keyword(s):  
Synaptic Plasticity ◽  
Somatosensory Cortex ◽  
Pyramidal Neurons ◽  
Layer 2

In vivo patch clamp analysis of synaptic responses evoked in primary somatosensory cortex in inflamed rats

2007 ◽  
Vol 58 ◽  
pp. S158
Author(s):  
Kohei Koga ◽  
Hiroaki Shiokawa ◽  
Masaharu Mizuno ◽  
Atsushi Doi ◽  
Hiroko Takase-Mizuguchi ◽  
...  
Keyword(s):  
Patch Clamp ◽  
Somatosensory Cortex ◽  
Primary Somatosensory Cortex ◽  
Synaptic Responses

In vivo two-photon calcium imaging of neuronal activities in primary somatosensory cortex in inflammatory chronic pain

2009 ◽  
Vol 65 ◽  
pp. S179
Author(s):  
Kei Eto ◽  
Hiroaki Wake ◽  
Hitoshi Ishibashi ◽  
Mami Noda ◽  
Junichi Nabekura
Keyword(s):  
Chronic Pain ◽  
Somatosensory Cortex ◽  
Calcium Imaging ◽  
Primary Somatosensory Cortex ◽  
Two Photon

scholarly journals Direct Activation of Cortical Neurons in the Primary Somatosensory Cortex of the Rat in Vivo Using Focused Ultrasound

2020 ◽  
Vol 46 (9) ◽  
pp. 2349-2360
Author(s):  
Kush Tripathi ◽  
Tongsheng Zhang ◽  
Nathan McDannold ◽  
Yong-Zhi Zhang ◽  
Gösta Ehnholm ◽  
...  
Keyword(s):  
Somatosensory Cortex ◽  
Cortical Neurons ◽  
Focused Ultrasound ◽  
Primary Somatosensory Cortex ◽  
Direct Activation

The effects of L-AP4 and l-serine-O-phosphate on inhibition in primary somatosensory cortex of the adult rat in vivo

1995 ◽  
Vol 34 (8) ◽  
pp. 1053-1062 ◽  
Author(s):  
H. Wan ◽  
P.M.B. Cahusac
Keyword(s):  
Somatosensory Cortex ◽  
Primary Somatosensory Cortex ◽  
Adult Rat
Sign in / Sign up

Export Citation Format

Share Document